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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Deciphering Spinal Endogenous Dopaminergic Mechanisms That Modulate Micturition Reflexes in Rats with Spinal Cord Injury

Shaoping Hou, Jaclyn H. DeFinis, Stephanie L. Daugherty, Chuanxi Tang, Jeremy Weinberger and William C. de Groat
eNeuro 8 July 2021, 8 (4) ENEURO.0157-21.2021; https://doi.org/10.1523/ENEURO.0157-21.2021
Shaoping Hou
1Marion Murray Spinal Cord Research Center, Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129
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Jaclyn H. DeFinis
1Marion Murray Spinal Cord Research Center, Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129
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Stephanie L. Daugherty
2Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261
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Chuanxi Tang
1Marion Murray Spinal Cord Research Center, Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129
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Jeremy Weinberger
1Marion Murray Spinal Cord Research Center, Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129
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William C. de Groat
2Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0157-21.2021
PubMed 
34244339
Published By 
Society for Neuroscience
History 
  • Received April 12, 2021
  • Revision received June 3, 2021
  • Accepted June 30, 2021
  • Published online July 8, 2021.
Copyright & Usage 
Copyright © 2021 Hou et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Shaoping Hou1,
  2. Jaclyn H. DeFinis1,
  3. Stephanie L. Daugherty2,
  4. Chuanxi Tang1,
  5. Jeremy Weinberger1 and
  6. William C. de Groat2
  1. 1Marion Murray Spinal Cord Research Center, Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129
  2. 2Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261
  1. Correspondence should be addressed to Shaoping Hou at sh698{at}drexel.edu.
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Author contributions

  1. Author contributions: S.H. and W.C.d.G. designed research; S.H., J.H.D., S.L.D., C.T., and J.W. performed research; S.H., J.H.D., S.L.D., C.T., and J.W. analyzed data; S.H., W.C.d.G., and J.H.D. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by National Institutes of Health National Institute of Neurological Disorders and Stroke Grant R01NS099076 (to S.H.) and National Institute of Diabetes and Digestive and Kidney Diseases Grants F31DK123840-01 (to J.H.D.) and PO1DK093424 (to W.C.d.G.).

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    R01NS099076
  • HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    F31DK123840-01; PO1DK093424

Other Version

  • You are viewing the most recent version of this article.
  • previous version (July 08, 2021).

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Article usage: July 2021 to May 2025

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Jul 202130741155
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Total 2021581958346
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Total 202451989196
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Mar 202568218
Apr 202547814
May 20251535
Total 20251937962
Total72641521033
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eneuro: 8 (4)
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Deciphering Spinal Endogenous Dopaminergic Mechanisms That Modulate Micturition Reflexes in Rats with Spinal Cord Injury
Shaoping Hou, Jaclyn H. DeFinis, Stephanie L. Daugherty, Chuanxi Tang, Jeremy Weinberger, William C. de Groat
eNeuro 8 July 2021, 8 (4) ENEURO.0157-21.2021; DOI: 10.1523/ENEURO.0157-21.2021

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Deciphering Spinal Endogenous Dopaminergic Mechanisms That Modulate Micturition Reflexes in Rats with Spinal Cord Injury
Shaoping Hou, Jaclyn H. DeFinis, Stephanie L. Daugherty, Chuanxi Tang, Jeremy Weinberger, William C. de Groat
eNeuro 8 July 2021, 8 (4) ENEURO.0157-21.2021; DOI: 10.1523/ENEURO.0157-21.2021
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Keywords

  • bladder overactivity
  • bursting
  • detrusor-sphincter dyssynergia
  • dopamine receptor
  • tonic activity

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