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Research ArticleResearch Article: New Research, Disorders of the Nervous System

S1P2-Gα12 Signaling Controls Astrocytic Glutamate Uptake and Mitochondrial Oxygen Consumption

Deepa Jonnalagadda, Yasuyuki Kihara, Richard Rivera and Jerold Chun
eNeuro 23 April 2021, 8 (4) ENEURO.0040-21.2021; https://doi.org/10.1523/ENEURO.0040-21.2021
Deepa Jonnalagadda
Translational Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037
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  • ORCID record for Deepa Jonnalagadda
Yasuyuki Kihara
Translational Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037
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Richard Rivera
Translational Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037
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Jerold Chun
Translational Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0040-21.2021
PubMed 
33893167
Published By 
Society for Neuroscience
History 
  • Received January 28, 2021
  • Revision received April 6, 2021
  • Accepted April 12, 2021
  • Published online April 23, 2021.
Copyright & Usage 
Copyright © 2021 Jonnalagadda et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Deepa Jonnalagadda*,
  2. Yasuyuki Kihara*,
  3. Richard Rivera and
  4. Jerold Chun
  1. Translational Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037
  1. Correspondence should be addressed to Jerold Chun at jchun{at}sbpdiscovery.org.
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Author contributions

  1. Author contributions: D.J., Y.K., and J.C. designed research; D.J., Y.K., and R.R. performed research; D.J. and Y.K. analyzed data; D.J., Y.K., and J.C. wrote the paper.

  2. ↵* D.J. and Y.K. contributed equally to this work.

Disclosures

  • J.C. has received honoraria, consulting fees, and/or grant support from Celgene, Arena Pharmaceuticals, Ono Pharmaceuticals and Novartis. All other authors declare no competing financial interests.

  • This work was supported by non-federal funds from Novartis (J.C.). This work was also supported by the National Institutes of Health/National Institute of Neurological Disorders and Stroke Grant R01NS103940 and postdoctoral fellowships to Y.K. (The Uehara Memorial Foundation, the Kanae Foundation for the Promotion of Medical Science, Mochida Memorial Foundation for Medical and Pharmaceutical Research, and the Human Frontier Science Program).

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    R01NS103940
  • Novartis Pharmaceuticals Corporation (NPC)

Other Version

  • You are viewing the most recent version of this article.
  • previous version (April 23, 2021).

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AbstractFullPdf
Apr 2021312089
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Jun 2021306065
Jul 2021218276106
Aug 20214141786
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Total 202113601279665
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Apr 202228537
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Jul 202226217
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Jan 202324823
Feb 20230859
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Apr 202348615
May 20235958
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Total 2023501139215
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Jun 2024411825
Jul 202429922
Aug 202498934
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Total 2024581250268
Jan 202549940
Feb 202589922
Mar 2025210526
Apr 202538115
May 202529124
Jun 202586214
Total 202527537141
Total154751321676
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eneuro: 8 (4)
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Vol. 8, Issue 4
July/August 2021
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S1P2-Gα12 Signaling Controls Astrocytic Glutamate Uptake and Mitochondrial Oxygen Consumption
Deepa Jonnalagadda, Yasuyuki Kihara, Richard Rivera, Jerold Chun
eNeuro 23 April 2021, 8 (4) ENEURO.0040-21.2021; DOI: 10.1523/ENEURO.0040-21.2021

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S1P2-Gα12 Signaling Controls Astrocytic Glutamate Uptake and Mitochondrial Oxygen Consumption
Deepa Jonnalagadda, Yasuyuki Kihara, Richard Rivera, Jerold Chun
eNeuro 23 April 2021, 8 (4) ENEURO.0040-21.2021; DOI: 10.1523/ENEURO.0040-21.2021
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