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Research ArticleResearch Article: New Research, Sensory and Motor Systems

Environmental Enrichment Sharpens Sensory Acuity by Enhancing Information Coding in Barrel Cortex and Premotor Cortex

He J. V. Zheng, Jesse P. Meagher, Duo Xu, Yogi A. Patel, Daniel H. O’Connor and Hyung-Bae Kwon
eNeuro 23 April 2021, 8 (3) ENEURO.0309-20.2021; https://doi.org/10.1523/ENEURO.0309-20.2021
He J. V. Zheng
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
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Jesse P. Meagher
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
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Duo Xu
2Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205
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Yogi A. Patel
3Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332
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Daniel H. O’Connor
2Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205
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Hyung-Bae Kwon
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
2Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205
4Max Planck Institute of Neurobiology, Martinsried 82152, Germany
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0309-20.2021
PubMed 
33893166
Published By 
Society for Neuroscience
History 
  • Received July 10, 2020
  • Revision received April 13, 2021
  • Accepted April 17, 2021
  • Published online April 23, 2021.
Copyright & Usage 
Copyright © 2021 Zheng et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. He J. V. Zheng1,
  2. Jesse P. Meagher1,
  3. Duo Xu2,
  4. Yogi A. Patel3,
  5. Daniel H. O’Connor2 and
  6. Hyung-Bae Kwon1,2,4
  1. 1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
  2. 2Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205
  3. 3Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332
  4. 4Max Planck Institute of Neurobiology, Martinsried 82152, Germany
  1. Correspondence should be addressed to Hyung-Bae Kwon at hkwon29{at}jhmi.edu.
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Author contributions

  1. Author contributions: H.J.V.Z. and H-B.K. designed research; H.J.V.Z. and J.P.M. performed research; H.J.V.Z., D.X., Y.A.P., and D.H.O. contributed unpublished reagents/analytic tools; H.J.V.Z. analyzed data; H.J.V.Z. and H-B.K. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the Max Planck Florida Institute for Neuroscience (H-B.K.) and National Institutes of Health Grants R01MH107460 and DP1MH119428 (to H-B.K.); R01NS089652 and 1R01NS104834-01 (D.H.O.).

Funding

  • HHS | NIH | National Institute of Mental Health (NIMH)

    107460; 119428

Other Version

  • You are viewing the most recent version of this article.
  • previous version (April 23, 2021).

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Total97547881027
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eneuro: 8 (3)
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May/June 2021
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Environmental Enrichment Sharpens Sensory Acuity by Enhancing Information Coding in Barrel Cortex and Premotor Cortex
He J. V. Zheng, Jesse P. Meagher, Duo Xu, Yogi A. Patel, Daniel H. O’Connor, Hyung-Bae Kwon
eNeuro 23 April 2021, 8 (3) ENEURO.0309-20.2021; DOI: 10.1523/ENEURO.0309-20.2021

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Environmental Enrichment Sharpens Sensory Acuity by Enhancing Information Coding in Barrel Cortex and Premotor Cortex
He J. V. Zheng, Jesse P. Meagher, Duo Xu, Yogi A. Patel, Daniel H. O’Connor, Hyung-Bae Kwon
eNeuro 23 April 2021, 8 (3) ENEURO.0309-20.2021; DOI: 10.1523/ENEURO.0309-20.2021
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Keywords

  • enriched environment
  • premotor cortex
  • somatosensory cortex
  • tuning heterogeneity
  • two-photon imaging
  • whisker discrimination task

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