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History
- Received November 2, 2020
- Revision received March 3, 2021
- Accepted March 9, 2021
- Published online March 24, 2021.
Copyright & Usage
Copyright © 2021 Adachi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
Author Information
- Toma Adachi1,2,
- Satoshi Miyashita1,
- Mariko Yamashita1,3,
- Mana Shimoda1,2,
- Konstantin Okonechnikov4,5,
- Lukas Chavez6,7,
- Marcel Kool4,5,8,
- Stefan M. Pfister4,5,9,
- Takafumi Inoue2,
- Daisuke Kawauchi1 and
- Mikio Hoshino1
- 1Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo 187-8551, Japan
- 2Department of Life Science and Medical Bioscience, School of Advanced Science and Engineering, Waseda University, Tokyo 169-8555, Japan
- 3Department of NCNP Brain Function and Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, TMDU, Tokyo 113-8510, Japan
- 4Hopp-Children’s Cancer Center Heidelberg (KiTZ), 69120 Heidelberg, Germany
- 5Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany
- 6Department of Medicine, University of California San Diego, La Jolla, CA 92093
- 7Moores Cancer Center, University of California San Diego, La Jolla, CA 92093
- 8Princess Maxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands
- 9Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, 69120 Heidelberg, Germany
- Correspondence should be addressed to Satoshi Miyashita at miyasatoshi{at}ncnp.go.jp or Mikio Hoshino at hoshino{at}ncnp.go.jp.
Author contributions
Author contributions: T.A., S.M., L.C., M.K., S.M.P., T.I., D.K., and M.H. designed research; T.A., S.M., M.Y., and M.S. performed research; T.A., S.M., K.O., and D.K. analyzed data; T.A. and M.H. wrote the paper.
Disclosures
The authors declare no competing financial interests.
This work was supported by Japan Society for the Promotion of Science Grants 18H02538 and 16H06528 (to M.H.), 20K15919 (to S.M.), and 18J20309 (to T.A.); the Japan Agency for Medical Research and Development Grant JP20dm0107085h0001 (to M.H.); Intramural Research Grants 27-7 and 28-4 (to M.H.); and the Heidelberg Center for Personalized Medicine Grant H065.
Funding
Japan Society for the Promotion of Science (JSPS)
18H02538; 16H06528; 20K15919; 18J20309Japan Agency for Medical Research and Development (AMED)
JP20dm0107085h0001Intramural Research Grants
27-7; 28-4Heidelberg center for Personalized Medicine
H065
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