Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleResearch Article: New Research, Neuronal Excitability

Retrograde Suppression of Post-Tetanic Potentiation at the Mossy Fiber-CA3 Pyramidal Cell Synapse

Sachin Makani, Stefano Lutzu, Pablo J. Lituma, David L. Hunt and Pablo E. Castillo
eNeuro 16 February 2021, 8 (2) ENEURO.0450-20.2021; https://doi.org/10.1523/ENEURO.0450-20.2021
Sachin Makani
1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stefano Lutzu
1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pablo J. Lituma
1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David L. Hunt
1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pablo E. Castillo
1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461
2Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY 10461
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0450-20.2021
PubMed 
33593734
Published By 
Society for Neuroscience
History 
  • Received October 19, 2020
  • Revision received December 17, 2020
  • Accepted January 16, 2021
  • Published online February 16, 2021.
Copyright & Usage 
Copyright © 2021 Makani et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Sachin Makani1,*,
  2. Stefano Lutzu1,*,
  3. Pablo J. Lituma1,*,
  4. David L. Hunt1 and
  5. Pablo E. Castillo1,2
  1. 1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461
  2. 2Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY 10461
  1. Correspondence should be addressed to Pablo E. Castillo at pablo.castillo{at}einsteinmed.org.
  • D. L. Hunt’s present address: Center for Neural Science and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048.

View Full Text

Author contributions

  1. Author contributions: S.M., S.L., P.J.L., D.L.H., and P.E.C. designed research; S.M., S.L., and P.J.L. performed research; S.M., S.L., and P.J.L. analyzed data; S.M., S.L., P.J.L., and P.E.C. wrote the paper.

  2. ↵* S.M., S.L., and P.J.L. contributed equally for this work.

  • D. L. Hunt’s present address: Center for Neural Science and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048.

Disclosures

  • The authors declare no competing financial interests.

  • This work supported by National Institutes of Health Grants F32-NS077696 (to S.M.) and R01-DA17392, R01 MH116673, and NIH R01MH125772 (to P.E.C.). S.M. was partially supported by the National Institutes of Health Grant T32-NS007439.

Funding

  • HHS | NIH | National Institute of Mental Health (NIMH)

    R01-MH125772; R01-MH116673
  • NIH

    F32-NS077696

Other Version

  • You are viewing the most recent version of this article.
  • previous version (February 16, 2021).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2026-01-15
to
E.g., 2026-01-15

Article usage: February 2021 to January 2026

AbstractFullPdf
Feb 2021220046
Mar 2021441294142
Apr 20215723326
May 20212320327
Jun 20211720927
Jul 2021917426
Aug 20211017513
Sep 202169422
Oct 2021610632
Nov 202138926
Dec 202149021
Total 20217961667408
Jan 202239616
Feb 202235117
Mar 202227625
Apr 202216019
May 202218018
Jun 20222828
Jul 202205819
Aug 202226410
Sep 202223416
Oct 202255818
Nov 202225824
Dec 20222549
Total 202225771199
Jan 20232569
Feb 20233687
Mar 202326313
Apr 20230767
May 20232726
Jun 20232835
Jul 202319114
Aug 202336715
Sep 202357113
Oct 20232967
Nov 20231928
Dec 202319115
Total 202324926119
Jan 202428412
Feb 202457111
Mar 20247789
Apr 202498821
May 202439713
Jun 202477321
Jul 202448918
Aug 2024117416
Sep 202497811
Oct 202438114
Nov 20240839
Dec 202429114
Total 202462987169
Jan 202538117
Feb 202571137
Mar 202579824
Apr 20251925
May 202519826
Jun 202599010
Jul 202529210
Aug 202549426
Sep 2025319912
Oct 2025910924
Nov 20251615318
Dec 2025812829
Total 2025701347208
Jan 20263555
Total 20263555
Total98057531108
Back to top

In this issue

eneuro: 8 (2)
eNeuro
Vol. 8, Issue 2
March/April 2021
  • Table of Contents
  • Index by author
  • Ed Board (PDF)
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Retrograde Suppression of Post-Tetanic Potentiation at the Mossy Fiber-CA3 Pyramidal Cell Synapse
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Retrograde Suppression of Post-Tetanic Potentiation at the Mossy Fiber-CA3 Pyramidal Cell Synapse
Sachin Makani, Stefano Lutzu, Pablo J. Lituma, David L. Hunt, Pablo E. Castillo
eNeuro 16 February 2021, 8 (2) ENEURO.0450-20.2021; DOI: 10.1523/ENEURO.0450-20.2021

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Retrograde Suppression of Post-Tetanic Potentiation at the Mossy Fiber-CA3 Pyramidal Cell Synapse
Sachin Makani, Stefano Lutzu, Pablo J. Lituma, David L. Hunt, Pablo E. Castillo
eNeuro 16 February 2021, 8 (2) ENEURO.0450-20.2021; DOI: 10.1523/ENEURO.0450-20.2021
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
    • Synthesis
    • Author Response
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • calcium
  • hippocampus
  • mossy fiber
  • presynaptic
  • retrograde signaling
  • Short-term plasticity

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Research Article: New Research

  • Independent encoding of orientation and mean luminance by mouse visual cortex
  • Neck Vascular Biomechanical Dysfunction Precedes Brain Biochemical Alterations in a Murine Model of Alzheimer’s Disease
  • Alpha-2 Adrenergic Agonists Reduce Heavy Alcohol Drinking and Improve Cognitive Performance in Mice
Show more Research Article: New Research

Neuronal Excitability

  • Altered Excitability and Glutamatergic Synaptic Transmission in the Medium Spiny Neurons of the Nucleus Accumbens in Mice Deficient in the Heparan Sulfate Endosulfatase Sulf1
  • Intrinsic Cell-Class–Specific Modulation of Intracellular Chloride Levels and Inhibitory Function, in Cortical Networks, between Day and Night
  • Individual Variation in Intrinsic Neuronal Properties of Nucleus Accumbens Core and Shell Medium Spiny Neurons in Male Rats Prone to Sign- or Goal-Track
Show more Neuronal Excitability

Subjects

  • Neuronal Excitability
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2026 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.