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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Mapping Sex-Specific Neurodevelopmental Alterations in Neurite Density and Morphology in a Rat Genetic Model of Psychiatric Illness

Brian R. Barnett, Sue Y. Yi, McKenzie J. Poetzel, Keith Dodd, Nicholas A. Stowe and John-Paul J. Yu
eNeuro 13 January 2021, 8 (2) ENEURO.0426-20.2020; https://doi.org/10.1523/ENEURO.0426-20.2020
Brian R. Barnett
1Neuroscience Training Program, Wisconsin Institutes for Medical Research, University of Wisconsin–Madison, Madison, WI 53705
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Sue Y. Yi
1Neuroscience Training Program, Wisconsin Institutes for Medical Research, University of Wisconsin–Madison, Madison, WI 53705
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  • ORCID record for Sue Y. Yi
McKenzie J. Poetzel
2Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705
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Keith Dodd
2Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705
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Nicholas A. Stowe
2Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705
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John-Paul J. Yu
1Neuroscience Training Program, Wisconsin Institutes for Medical Research, University of Wisconsin–Madison, Madison, WI 53705
2Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705
3Department of Biomedical Engineering, College of Engineering, University of Wisconsin–Madison, Madison, WI 53706
4Department of Psychiatry, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0426-20.2020
PubMed 
33441401
Published By 
Society for Neuroscience
History 
  • Received September 30, 2020
  • Revision received November 19, 2020
  • Accepted December 28, 2020
  • Published online January 13, 2021.
Copyright & Usage 
Copyright © 2021 Barnett et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Brian R. Barnett1,
  2. Sue Y. Yi1,
  3. McKenzie J. Poetzel2,
  4. Keith Dodd2,
  5. Nicholas A. Stowe2 and
  6. John-Paul J. Yu1,2,3,4
  1. 1Neuroscience Training Program, Wisconsin Institutes for Medical Research, University of Wisconsin–Madison, Madison, WI 53705
  2. 2Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705
  3. 3Department of Biomedical Engineering, College of Engineering, University of Wisconsin–Madison, Madison, WI 53706
  4. 4Department of Psychiatry, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705
  1. Correspondence should be addressed to John-Paul J. Yu at jpyu{at}uwhealth.org.
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Author contributions

  1. Author contributions: B.R.B., S.Y.Y., and J.-P.J.Y. designed research; B.R.B., S.Y.Y., M.J.P., K.D., and N.A.S. performed research; B.R.B., S.Y.Y., N.A.S., and J.-P.J.Y. analyzed data; B.R.B. and J.-P.J.Y. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • J.-P.J.Y. was supported by the Clinical and Translational Science Award program through the National Institutes of Health National Center for Advancing Translational Sciences Grant UL1TR002373. Additional imaging support was provided by the University of Wisconsin Carbone Cancer Center Support Grant P30CA014520 and Waisman Core Grants P30 HD003352-45 and U54 AI117924-03.

Funding

  • NIH/NCATS

    UL1TR002373

Other Version

  • You are viewing the most recent version of this article.
  • previous version (January 13, 2021).

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Jan 2021482080
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Total 20251201233226
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Total 20265579
Total102955181029
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eneuro: 8 (2)
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March/April 2021
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Mapping Sex-Specific Neurodevelopmental Alterations in Neurite Density and Morphology in a Rat Genetic Model of Psychiatric Illness
Brian R. Barnett, Sue Y. Yi, McKenzie J. Poetzel, Keith Dodd, Nicholas A. Stowe, John-Paul J. Yu
eNeuro 13 January 2021, 8 (2) ENEURO.0426-20.2020; DOI: 10.1523/ENEURO.0426-20.2020

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Mapping Sex-Specific Neurodevelopmental Alterations in Neurite Density and Morphology in a Rat Genetic Model of Psychiatric Illness
Brian R. Barnett, Sue Y. Yi, McKenzie J. Poetzel, Keith Dodd, Nicholas A. Stowe, John-Paul J. Yu
eNeuro 13 January 2021, 8 (2) ENEURO.0426-20.2020; DOI: 10.1523/ENEURO.0426-20.2020
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Keywords

  • diffusion-weighted imaging
  • Disc1
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  • MRI
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