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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Time Course of Alterations in Adult Spinal Motoneuron Properties in the SOD1(G93A) Mouse Model of ALS

Seoan Huh, Charles J. Heckman and Marin Manuel
eNeuro 25 February 2021, 8 (2) ENEURO.0378-20.2021; https://doi.org/10.1523/ENEURO.0378-20.2021
Seoan Huh
1Department of Physiology, Northwestern University, Feinberg School of Medicine, Chicago 60611, IL
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Charles J. Heckman
1Department of Physiology, Northwestern University, Feinberg School of Medicine, Chicago 60611, IL
2Department of Physical Medicine and Rehabilitation, Northwestern University, Feinberg School of Medicine, Chicago 60611, IL
3Department of Physical Therapy and Human Movement Science, Northwestern University, Feinberg School of Medicine, Chicago 60611, IL
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Marin Manuel
1Department of Physiology, Northwestern University, Feinberg School of Medicine, Chicago 60611, IL
4Université de Paris, Saints-Pères Paris Institute for the Neurosciences (SPPIN), Centre National de la Recherche Scientifique, Paris 75006, France
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0378-20.2021
PubMed 
33632815
Published By 
Society for Neuroscience
History 
  • Received August 30, 2020
  • Revision received January 25, 2021
  • Accepted January 26, 2021
  • Published online February 25, 2021.
Copyright & Usage 
Copyright © 2021 Huh et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Seoan Huh1,
  2. Charles J. Heckman1,2,3 and
  3. Marin Manuel1,4
  1. 1Department of Physiology, Northwestern University, Feinberg School of Medicine, Chicago 60611, IL
  2. 2Department of Physical Medicine and Rehabilitation, Northwestern University, Feinberg School of Medicine, Chicago 60611, IL
  3. 3Department of Physical Therapy and Human Movement Science, Northwestern University, Feinberg School of Medicine, Chicago 60611, IL
  4. 4Université de Paris, Saints-Pères Paris Institute for the Neurosciences (SPPIN), Centre National de la Recherche Scientifique, Paris 75006, France
  1. Correspondence should be addressed to Marin Manuel at marin.manuel{at}neurobio.org.
View Full Text

Author contributions

  1. Author contributions: C.J.H. and M.M. designed research; S.H. performed research; S.H. and M.M. analyzed data; S.H., C.J.H., and M.M. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by National Institutes of Health National Institute of Neurological Disorders and Stroke Grants R01NS077863 and R01NS110953. S.H. was supported by the National Science Foundation Graduate Research Fellowship.

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    R01NS077863; R01NS110953
  • National Science Foundation (NSF)

Other Version

  • You are viewing the most recent version of this article.
  • previous version (February 25, 2021).

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Article usage: February 2021 to July 2025

AbstractFullPdf
Feb 202160030
Mar 2021345141124
Apr 202110830768
May 20213521637
Jun 20212521229
Jul 2021718214
Aug 20211417814
Sep 2021411428
Oct 2021109836
Nov 2021212329
Dec 202158319
Total 20216151654428
Jan 202249919
Feb 20222457
Mar 2022130723
Apr 2022454024
May 202228115
Jun 202227510
Jul 202225810
Aug 202205310
Sep 202257117
Oct 2022648017
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Total 2022352085179
Jan 202326817
Feb 20230707
Mar 20232727
Apr 20230718
May 20232646
Jun 20232788
Jul 202319113
Aug 202328620
Sep 202388819
Oct 20231010016
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Total 2023351005156
Jan 202417312
Feb 202477315
Mar 202497914
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May 202419014
Jun 2024118810
Jul 2024610122
Aug 202458123
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Total 2024671083174
Jan 20251410321
Feb 20254899
Mar 202529717
Apr 202549511
May 202508418
Jun 202548710
Jul 20253298
Total 20253158494
Total78364111031
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eneuro: 8 (2)
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March/April 2021
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Time Course of Alterations in Adult Spinal Motoneuron Properties in the SOD1(G93A) Mouse Model of ALS
Seoan Huh, Charles J. Heckman, Marin Manuel
eNeuro 25 February 2021, 8 (2) ENEURO.0378-20.2021; DOI: 10.1523/ENEURO.0378-20.2021

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Time Course of Alterations in Adult Spinal Motoneuron Properties in the SOD1(G93A) Mouse Model of ALS
Seoan Huh, Charles J. Heckman, Marin Manuel
eNeuro 25 February 2021, 8 (2) ENEURO.0378-20.2021; DOI: 10.1523/ENEURO.0378-20.2021
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Keywords

  • ALS
  • electrophysiology
  • homeostasis
  • in vivo recording
  • motor neuron
  • spinal cord

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