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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Altered Fast Synaptic Transmission in a Mouse Model of DNM1-Associated Developmental Epileptic Encephalopathy

Matthew P. McCabe, Amy N. Shore, Wayne N. Frankel and Matthew C. Weston
eNeuro 28 December 2020, 8 (2) ENEURO.0269-20.2020; https://doi.org/10.1523/ENEURO.0269-20.2020
Matthew P. McCabe
1Department of Neurological Sciences, Larner College of Medicine, University of Vermont, Burlington, VT 05405
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Amy N. Shore
1Department of Neurological Sciences, Larner College of Medicine, University of Vermont, Burlington, VT 05405
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Wayne N. Frankel
2Department of Genetics and Development, Institute for Genomic Medicine, Columbia University, New York, NY 10032
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Matthew C. Weston
1Department of Neurological Sciences, Larner College of Medicine, University of Vermont, Burlington, VT 05405
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0269-20.2020
PubMed 
33372033
Published By 
Society for Neuroscience
History 
  • Received June 12, 2020
  • Revision received December 1, 2020
  • Accepted December 7, 2020
  • Published online December 28, 2020.
Copyright & Usage 
Copyright © 2021 McCabe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Matthew P. McCabe1,
  2. Amy N. Shore1,
  3. Wayne N. Frankel2 and
  4. Matthew C. Weston1
  1. 1Department of Neurological Sciences, Larner College of Medicine, University of Vermont, Burlington, VT 05405
  2. 2Department of Genetics and Development, Institute for Genomic Medicine, Columbia University, New York, NY 10032
  1. Correspondence should be addressed to Matthew C. Weston at mcweston{at}uvm.edu.
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Author contributions

  1. Author contributions: M.P.M., W.N.F., and M.C.W. designed research; M.P.M., A.N.S., and M.C.W. performed research; M.P.M., A.N.S., and M.C.W. analyzed data; M.P.M. and M.C.W. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by National Institutes of Health/ National Institute of Neurological Disorders and Stroke Grants NS087095 (to M.C.W.), NS110945 (to M.C.W.), and NS031348 (and W.N.F.).

Funding

  • NINDS

    NS110945
  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    NS087095; NS031348

Other Version

  • You are viewing the most recent version of this article.
  • previous version (December 28, 2020).

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Article usage: December 2020 to May 2026

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Dec 202069026
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Total 2025521249365
Jan 20261215222
Feb 2026819419
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Total 202640771152
Total83964461938
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eneuro: 8 (2)
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March/April 2021
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Altered Fast Synaptic Transmission in a Mouse Model of DNM1-Associated Developmental Epileptic Encephalopathy
Matthew P. McCabe, Amy N. Shore, Wayne N. Frankel, Matthew C. Weston
eNeuro 28 December 2020, 8 (2) ENEURO.0269-20.2020; DOI: 10.1523/ENEURO.0269-20.2020

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Altered Fast Synaptic Transmission in a Mouse Model of DNM1-Associated Developmental Epileptic Encephalopathy
Matthew P. McCabe, Amy N. Shore, Wayne N. Frankel, Matthew C. Weston
eNeuro 28 December 2020, 8 (2) ENEURO.0269-20.2020; DOI: 10.1523/ENEURO.0269-20.2020
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Keywords

  • cell death
  • dynamin
  • encephalopathy
  • epilepsy
  • network activity
  • synaptic transmission

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