Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleResearch Article: New Research, Disorders of the Nervous System

α-Synuclein Aggregates Increase the Conductance of Substantia Nigra Dopamine Neurons, an Effect Partly Reversed by the KATP Channel Inhibitor Glibenclamide

E. Hill, R. Gowers, M. J. E. Richardson and M. J. Wall
eNeuro 23 November 2020, 8 (1) ENEURO.0330-20.2020; https://doi.org/10.1523/ENEURO.0330-20.2020
E. Hill
1School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdoms
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R. Gowers
2Warwick Mathematics Institute, University of Warwick, Coventry CV4 7AL, United Kingdom
3Institute for Theoretical Biology, Department of Biology, Humboldt-Universität zu Berlin, Berlin 10115, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. J. E. Richardson
2Warwick Mathematics Institute, University of Warwick, Coventry CV4 7AL, United Kingdom
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. J. Wall
1School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdoms
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0330-20.2020
PubMed 
33229413
Published By 
Society for Neuroscience
History 
  • Received July 27, 2020
  • Revision received October 13, 2020
  • Accepted October 18, 2020
  • Published online November 23, 2020.
Copyright & Usage 
Copyright © 2021 Hill et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. E. Hill1,
  2. R. Gowers2,3,
  3. M. J. E. Richardson2 and
  4. M. J. Wall1
  1. 1School of Life Sciences, University of Warwick, Coventry CV4 7AL, United Kingdoms
  2. 2Warwick Mathematics Institute, University of Warwick, Coventry CV4 7AL, United Kingdom
  3. 3Institute for Theoretical Biology, Department of Biology, Humboldt-Universität zu Berlin, Berlin 10115, Germany
  1. Correspondence should be addressed to M. J. Wall at mark.wall{at}warwick.ac.uk.
View Full Text

Author contributions

  1. Author contributions: E.H., M.J.E.R., and M.J.W. designed research; E.H. performed research; E.H., R.G., and M.J.E.R. analyzed data; E.H., R.G., M.J.E.R., and M.J.W. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by Biotechnology and Biological Science Research Council-funded PhD Studentship (E.H.) an Engineering and Physical Sciences Research Council-funded PhD Studentship (R.G.).

Funding

  • BBSRC

  • Engineering and Physical Sciences Research Council (EPSRC)

Other Version

  • You are viewing the most recent version of this article.
  • previous version (November 23, 2020).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2026-03-09
to
E.g., 2026-03-09

Article usage: November 2020 to March 2026

AbstractFullPdf
Nov 20203370135
Dec 20205040298
Total 20208410433
Jan 2021161227122
Feb 202147716174
Mar 20212642068
Apr 20213126628
May 2021924225
Jun 20211123427
Jul 2021213321
Aug 2021916327
Sep 2021511826
Oct 2021512424
Nov 2021114230
Dec 2021712730
Total 20213142912602
Jan 20221416419
Feb 2022510226
Mar 2022312831
Apr 202258718
May 2022111824
Jun 2022310712
Jul 2022310831
Aug 202248018
Sep 202216823
Oct 202245812
Nov 202249822
Dec 202216013
Total 2022481178249
Jan 202338318
Feb 202317210
Mar 202329512
Apr 202318511
May 202308015
Jun 2023011215
Jul 202369415
Aug 202339924
Sep 20231111013
Oct 2023711519
Nov 2023610515
Dec 2023512127
Total 2023451171194
Jan 20245214527
Feb 2024111821
Mar 20241010824
Apr 2024623826
May 2024411133
Jun 2024511425
Jul 20241210526
Aug 202499217
Sep 2024610515
Oct 2024712022
Nov 2024313428
Dec 2024613031
Total 20241211520295
Jan 2025710433
Feb 2025514022
Mar 2025618633
Apr 2025813822
May 2025415116
Jun 20251013721
Jul 20251012525
Aug 2025913037
Sep 20251416336
Oct 20251320534
Nov 20251619225
Dec 20251025043
Total 20251121921347
Jan 20261321429
Feb 20261427522
Mar 202634526
Total 20263053477
Total151192362197
Back to top

In this issue

eneuro: 8 (1)
eNeuro
Vol. 8, Issue 1
January/February 2021
  • Table of Contents
  • Index by author
  • Ed Board (PDF)
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
α-Synuclein Aggregates Increase the Conductance of Substantia Nigra Dopamine Neurons, an Effect Partly Reversed by the KATP Channel Inhibitor Glibenclamide
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
α-Synuclein Aggregates Increase the Conductance of Substantia Nigra Dopamine Neurons, an Effect Partly Reversed by the KATP Channel Inhibitor Glibenclamide
E. Hill, R. Gowers, M. J. E. Richardson, M. J. Wall
eNeuro 23 November 2020, 8 (1) ENEURO.0330-20.2020; DOI: 10.1523/ENEURO.0330-20.2020

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
α-Synuclein Aggregates Increase the Conductance of Substantia Nigra Dopamine Neurons, an Effect Partly Reversed by the KATP Channel Inhibitor Glibenclamide
E. Hill, R. Gowers, M. J. E. Richardson, M. J. Wall
eNeuro 23 November 2020, 8 (1) ENEURO.0330-20.2020; DOI: 10.1523/ENEURO.0330-20.2020
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Visual Abstract
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
    • Synthesis
    • Author Response
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • α-synuclein
  • dopamine
  • electrophysiology
  • KATP
  • patch clamp
  • substantia nigra

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Research Article: New Research

  • Robust representation and nonlinear spectral integration of harmonic stacks in layer 4 of mouse primary auditory cortex
  • Changes in palatability processing across the estrous cycle are modulated by hypothalamic estradiol signaling
  • Transcranial Static Magnetic Stimulation Dissociates the Causal Roles of the Parietal Cortex in Spatial and Temporal Processing
Show more Research Article: New Research

Disorders of the Nervous System

  • Functional-Structural Coupling: Brain Reorganization in Presbycusis Is Related to Cognitive Impairment
  • Investigating the Role of Cortical Microglia in a Mouse Model of Viral Infection-Induced Seizures
  • GABAB Receptor signaling in CA1 Pyramidal Cells is not Regulated by Aging in the APP/PS1 Mouse Model of Amyloid Pathology
Show more Disorders of the Nervous System

Subjects

  • Disorders of the Nervous System
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2026 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.