Molecular Diversity of Glutamatergic and GABAergic Synapses from Multiplexed Fluorescence Imaging

Eric Danielson; Karen Perez de Arce; Beth Cimini; Eike-Christian Wamhoff; Shantanu Singh; Jeffrey R. Cottrell; Anne E. Carpenter; Mark Bathe

doi:10.1523/ENEURO.0286-20.2020

Article Information

DOI

https://doi.org/10.1523/ENEURO.0286-20.2020

PubMed

33355295

Published By

Society for Neuroscience

History

Received June 29, 2020
Revision received November 25, 2020
Accepted December 7, 2020
Published online December 21, 2020.

Copyright © 2021 Danielson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

Eric Danielson¹,
Karen Perez de Arce²,
Beth Cimini³,
Eike-Christian Wamhoff¹,
Shantanu Singh³,
Jeffrey R. Cottrell²,
Anne E. Carpenter³ and
Mark Bathe¹

¹Department of Biological Engineering, MIT, Cambridge 02142, MA
²Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge 02142, MA
³Imaging Platform, Broad Institute of MIT and Harvard, Cambridge 02142, MA

Correspondence should be addressed to Anne E. Carpenter at anne{at}broadinstitute.org or Mark Bathe at mark.bathe{at}mit.edu.

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Author contributions

Author contributions: M.B., E.D., K.P.d.A., J.R.C., and A.E.C. designed research; E.D. and K.P.d.A. performed research; B.C. and E.-C.W. contributed unpublished reagents/analytic tools; E.D., K.P.d.A., B.C., and S.S. analyzed data; M.B., E.D., K.P.d.A., B.C., E.-C.W., S.S., J.R.C., and A.E.C. wrote the paper.

Disclosures

The authors declare no competing financial interests.
This work was supported by the National Institutes of Health Grant R01-MH112694 (to M.B. and J.R.C.) and the National Science Foundation Physics of Living Systems Grant 1707999 (to M.B.). J.R.C. was also supported by funding from the Stanley Center for Psychiatric Research.