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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Asparagine Endopeptidase (δ Secretase), an Enzyme Implicated in Alzheimer’s Disease Pathology, Is an Inhibitor of Axon Regeneration in Peripheral Nerves

Arthur W. English, Xia Liu, Olivia C. Mistretta, Patricia J. Ward and Keqiang Ye
eNeuro 15 December 2020, 8 (1) ENEURO.0155-20.2020; https://doi.org/10.1523/ENEURO.0155-20.2020
Arthur W. English
1Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322
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Xia Liu
2Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322
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Olivia C. Mistretta
1Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322
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Patricia J. Ward
1Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322
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Keqiang Ye
2Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0155-20.2020
PubMed 
33323399
Published By 
Society for Neuroscience
History 
  • Received April 24, 2020
  • Revision received November 20, 2020
  • Accepted November 23, 2020
  • Published online December 15, 2020.
Copyright & Usage 
Copyright © 2021 English et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Arthur W. English1,
  2. Xia Liu2,
  3. Olivia C. Mistretta1,
  4. Patricia J. Ward1 and
  5. Keqiang Ye2
  1. 1Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322
  2. 2Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322
  1. Correspondence should be addressed to Arthur W. English at medae{at}emory.edu.
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Author contributions

  1. Author contributions: A.W.E., P.J.W., and K.Y. designed research; X.L., O.C.M., and P.J.W. performed research; A.W.E., X.L., O.C.M., P.J.W., and K.Y. analyzed data; A.W.E. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by National Institutes of Health Grant NS105982 from the United States Public Health Service.

Funding

  • NINDS

    NS105982

Other Version

  • You are viewing the most recent version of this article.
  • previous version (December 15, 2020).

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Article usage: December 2020 to November 2025

AbstractFullPdf
Dec 2020234087
Total 2020234087
Jan 202151433399
Feb 20217620949
Mar 20214120126
Apr 20212022125
May 20211319312
Jun 20211021020
Jul 2021412528
Aug 202111939
Sep 2021511027
Oct 2021712237
Nov 2021710333
Dec 2021411335
Total 20217122033400
Jan 202259219
Feb 202275113
Mar 202248426
Apr 202258422
May 2022710736
Jun 202239120
Jul 202235310
Aug 202236913
Sep 202256315
Oct 202249823
Nov 20220508
Dec 20221456
Total 202247887211
Jan 202345316
Feb 20230628
Mar 202338411
Apr 202357110
May 20230669
Jun 20235699
Jul 202358214
Aug 202357728
Sep 202357412
Oct 2023159414
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Dec 2023410032
Total 202356914174
Jan 202437420
Feb 20245758
Mar 2024108620
Apr 2024118322
May 202439413
Jun 202498416
Jul 202499022
Aug 202488525
Sep 202438721
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Dec 202479034
Total 2024731023234
Jan 202578016
Feb 2025610717
Mar 2025110012
Apr 202568913
May 20256939
Jun 202588411
Jul 20251011738
Aug 2025129650
Sep 20251611622
Oct 20251910718
Nov 20254311
Total 2025951020207
Total121758771313
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January/February 2021
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Asparagine Endopeptidase (δ Secretase), an Enzyme Implicated in Alzheimer’s Disease Pathology, Is an Inhibitor of Axon Regeneration in Peripheral Nerves
Arthur W. English, Xia Liu, Olivia C. Mistretta, Patricia J. Ward, Keqiang Ye
eNeuro 15 December 2020, 8 (1) ENEURO.0155-20.2020; DOI: 10.1523/ENEURO.0155-20.2020

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Asparagine Endopeptidase (δ Secretase), an Enzyme Implicated in Alzheimer’s Disease Pathology, Is an Inhibitor of Axon Regeneration in Peripheral Nerves
Arthur W. English, Xia Liu, Olivia C. Mistretta, Patricia J. Ward, Keqiang Ye
eNeuro 15 December 2020, 8 (1) ENEURO.0155-20.2020; DOI: 10.1523/ENEURO.0155-20.2020
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Keywords

  • APP
  • asparagine endopeptidase
  • mouse
  • nerve
  • regeneration
  • tau

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