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Research ArticleResearch Article: New Research, Disorders of the Nervous System

ADAP1/Centaurin-α1 Negatively Regulates Dendritic Spine Function and Memory Formation in the Hippocampus

Erzsebet M. Szatmari, Corey Moran, Sarah Cohen, Amanda Jacob, Paula Parra-Bueno, Naomi Kamasawa, Debbie Guerrero-Given, Michael Klein, Robert Stackman Jr and Ryohei Yasuda
eNeuro 2 November 2020, 8 (1) ENEURO.0111-20.2020; https://doi.org/10.1523/ENEURO.0111-20.2020
Erzsebet M. Szatmari
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
2College of Allied Health Sciences, East Carolina University, Greenville, NC 27834
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Corey Moran
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
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Sarah Cohen
3Florida Atlantic University, Jupiter, FL 33458
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Amanda Jacob
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
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Paula Parra-Bueno
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
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Naomi Kamasawa
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
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  • ORCID record for Naomi Kamasawa
Debbie Guerrero-Given
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
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Michael Klein
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
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Robert Stackman Jr
3Florida Atlantic University, Jupiter, FL 33458
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Ryohei Yasuda
1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0111-20.2020
PubMed 
33139322
Published By 
Society for Neuroscience
History 
  • Received March 23, 2020
  • Revision received September 25, 2020
  • Accepted October 1, 2020
  • Published online November 2, 2020.
Copyright & Usage 
Copyright © 2021 Szatmari et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Erzsebet M. Szatmari1,2,
  2. Corey Moran1,
  3. Sarah Cohen3,
  4. Amanda Jacob1,
  5. Paula Parra-Bueno1,
  6. Naomi Kamasawa1,
  7. Debbie Guerrero-Given1,
  8. Michael Klein1,
  9. Robert Stackman Jr3 and
  10. Ryohei Yasuda1
  1. 1Max Planck Florida Institute for Neuroscience, Jupiter, FL 33458
  2. 2College of Allied Health Sciences, East Carolina University, Greenville, NC 27834
  3. 3Florida Atlantic University, Jupiter, FL 33458
  1. Correspondence should be addressed to Ryohei Yasuda at ryohei.yasuda{at}mpfi.org or Erzsebet Szatmari at szatmarie18{at}ecu.edu.
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Author contributions

  1. Author contributions: E.M.S. and R.Y. designed research; E.M.S., C.M., S.C., A.J., P.P.-B., N.K., D.G.-G., M.K., and R.S. performed research; E.M.S., C.M., S.C., A.J., P.P.-B., N.K., D.G.-G., M.K., R.S., and R.Y. analyzed data; E.M.S., N.K., and R.Y. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the BrightFocus Foundation, the Community Foundation of the Palm Beaches, the National Institutes of Health, and Max Planck Foundation.

Funding

  • HHS | NIH | National Institute on Minority Health and Health Disparities (NIMHD)

    R01MH080047
  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    DP1NS096787
  • BrightFocus Foundation (BrightFocus)

    A2015251S
  • Community Foundation for Palm Beach and Martin County

  • Brain Research Foundation (BRF)

    BRF-SIA-2018-01

Other Version

  • You are viewing the most recent version of this article.
  • previous version (November 02, 2020).

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Nov 20203120152
Dec 2020162064
Total 20204740216
Jan 202112726798
Feb 20213617929
Mar 20213023434
Apr 20212219018
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Jun 2021922016
Jul 2021711013
Aug 202169817
Sep 2021108711
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Total 20212651840327
Jan 202239821
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Apr 202298924
May 202247914
Jun 202238716
Jul 202235715
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Jul 202367415
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May 202448150
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Jul 202437216
Aug 202498218
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Jul 2025139720
Aug 2025109138
Sep 2025914621
Oct 20251012844
Nov 20251116425
Dec 2025717138
Total 2025841376283
Jan 2026129511
Total 2026129511
Total95859281467
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ADAP1/Centaurin-α1 Negatively Regulates Dendritic Spine Function and Memory Formation in the Hippocampus
Erzsebet M. Szatmari, Corey Moran, Sarah Cohen, Amanda Jacob, Paula Parra-Bueno, Naomi Kamasawa, Debbie Guerrero-Given, Michael Klein, Robert Stackman Jr, Ryohei Yasuda
eNeuro 2 November 2020, 8 (1) ENEURO.0111-20.2020; DOI: 10.1523/ENEURO.0111-20.2020

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ADAP1/Centaurin-α1 Negatively Regulates Dendritic Spine Function and Memory Formation in the Hippocampus
Erzsebet M. Szatmari, Corey Moran, Sarah Cohen, Amanda Jacob, Paula Parra-Bueno, Naomi Kamasawa, Debbie Guerrero-Given, Michael Klein, Robert Stackman Jr, Ryohei Yasuda
eNeuro 2 November 2020, 8 (1) ENEURO.0111-20.2020; DOI: 10.1523/ENEURO.0111-20.2020
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Keywords

  • ADAP1/Centaurin-α1
  • Arf6
  • dendritic spines
  • hippocampus
  • learning and memory

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