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Research ArticleResearch Article: New Research, Sensory and Motor Systems

The G-Protein-Coupled Receptor SRX-97 Is Required for Concentration-Dependent Sensing of Benzaldehyde in Caenorhabditis elegans

Nagesh Y. Kadam, Sukanta Behera, Sandeep Kumar, Anindya Ghosh-Roy and Kavita Babu
eNeuro 4 January 2021, 8 (1) ENEURO.0011-20.2020; https://doi.org/10.1523/ENEURO.0011-20.2020
Nagesh Y. Kadam
1Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Punjab 140306, India
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Sukanta Behera
1Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Punjab 140306, India
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Sandeep Kumar
3National Brain Research Centre, Manesar, Nainwal Mode, Gurgaon 122051, India
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Anindya Ghosh-Roy
3National Brain Research Centre, Manesar, Nainwal Mode, Gurgaon 122051, India
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Kavita Babu
1Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Punjab 140306, India
2Centre for Neuroscience, Indian Institute of Science, Bangalore 560012, India
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0011-20.2020
PubMed 
33397797
Published By 
Society for Neuroscience
History 
  • Received January 9, 2020
  • Revision received December 16, 2020
  • Accepted December 18, 2020
  • Published online January 4, 2021.
Copyright & Usage 
Copyright © 2021 Kadam et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Nagesh Y. Kadam1,
  2. Sukanta Behera1,
  3. Sandeep Kumar3,
  4. Anindya Ghosh-Roy3 and
  5. Kavita Babu1,2
  1. 1Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Punjab 140306, India
  2. 2Centre for Neuroscience, Indian Institute of Science, Bangalore 560012, India
  3. 3National Brain Research Centre, Manesar, Nainwal Mode, Gurgaon 122051, India
  1. Correspondence should be addressed to Kavita Babu at kavita.babu{at}babulab.org/kavitababu{at}iisc.ac.in or Nagesh Kadam at nagesh.kadam{at}babulab.org.
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Author contributions

  1. Author contributions: N.Y.K., A.G.-R., and K.B. designed research; N.Y.K., S.B., and S.K. performed research; N.Y.K. and S.B. analyzed data; N.Y.K. and K.B. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by Department of Biotechnology (DBT)/Wellcome Trust India Alliance Fellowships Gants IA/S/19/2/504649 and IA/I/12/1/500516 (to K.B.) and partially supported by DBT, Ministry of Human Resource Development- Scheme for Transformational and Advanced Research in Sciences and Department of Science and Technology-Science and Engineering Research Board Grants BT/PR24038/BRB/10/1693/2018, STARS/APR2019/BS/454/FS, and SERB/F/7047 as well as a DBT-IISc Partnership Grant (K.B.). Anindya Ghosh-Roy lab is supported by the National Brain Research Centre core fund from the Department of Biotechnology and the DBT/Wellcome Trust India Alliance Fellowship Grant IA/I/13/1/500874 (to A.G.-R.). A number of strains were provided by CGC, which is funded by the National Institutes of Health Office of Research Infrastructure Programs Grant P40 OD010440. N.Y.K. was funded by the Council of Scientific and Industrial Research (CSIR)-University Grants Commission (UGC) for a Graduate Fellowship. S.B. was funded by a Kisehore Vaigyanik Protsahan Yojanana Fellowship for undergraduate students.

Funding

  • India Alliance

    IA/I/12/1/500516; IA/I/13/1/500874; IA/S/19/2/504649
  • Department of Biotechnology , Ministry of Science and Technology (DBT)

    BT/PR24038/BRB/10/1693/2018
  • DST | Science and Engineering Research Board (SERB)

    SERB/F/7047
  • Ministry of Human Resource Development (MHRD)

    STARS/APR2019/BS/454/FS

Other Version

  • You are viewing the most recent version of this article.
  • previous version (January 04, 2021).

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Article usage: January 2021 to February 2026

AbstractFullPdf
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Apr 20212518816
May 20211020422
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Jul 202256110
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Jan 202316315
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May 202449824
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Total 2024741057225
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Aug 202589639
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Oct 2025119612
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Dec 20251415531
Total 2025991421303
Jan 2026918819
Feb 202642327
Total 20261342026
Total158368851435
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The G-Protein-Coupled Receptor SRX-97 Is Required for Concentration-Dependent Sensing of Benzaldehyde in Caenorhabditis elegans
Nagesh Y. Kadam, Sukanta Behera, Sandeep Kumar, Anindya Ghosh-Roy, Kavita Babu
eNeuro 4 January 2021, 8 (1) ENEURO.0011-20.2020; DOI: 10.1523/ENEURO.0011-20.2020

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The G-Protein-Coupled Receptor SRX-97 Is Required for Concentration-Dependent Sensing of Benzaldehyde in Caenorhabditis elegans
Nagesh Y. Kadam, Sukanta Behera, Sandeep Kumar, Anindya Ghosh-Roy, Kavita Babu
eNeuro 4 January 2021, 8 (1) ENEURO.0011-20.2020; DOI: 10.1523/ENEURO.0011-20.2020
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Keywords

  • ASH neuron
  • benzaldehyde
  • C. elegans
  • SRX-97

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