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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Chemogenetic Inhibition of Infralimbic Prefrontal Cortex GABAergic Parvalbumin Interneurons Attenuates the Impact of Chronic Stress in Male Mice

Nawshaba Nawreen, Evelin M. Cotella, Rachel Morano, Parinaz Mahbod, Khushali S. Dalal, Maureen Fitzgerald, Susan Martelle, Benjamin A. Packard, Ana Franco-Villanueva, Rachel D. Moloney and James P. Herman
eNeuro 14 October 2020, 7 (5) ENEURO.0423-19.2020; https://doi.org/10.1523/ENEURO.0423-19.2020
Nawshaba Nawreen
1Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45237-0506
2Neuroscience Graduate Program, University of Cincinnati, Cincinnati, OH 45237-0506
4Veterans Affairs Medical Center, Cincinnati, OH 45221-0506
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  • ORCID record for Nawshaba Nawreen
Evelin M. Cotella
1Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45237-0506
4Veterans Affairs Medical Center, Cincinnati, OH 45221-0506
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Rachel Morano
1Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45237-0506
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Parinaz Mahbod
1Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45237-0506
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Khushali S. Dalal
3College of Allied Health Sciences, University of Cincinnati, Cincinnati, OH 45237-0506
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Maureen Fitzgerald
1Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45237-0506
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Susan Martelle
1Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45237-0506
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Benjamin A. Packard
1Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45237-0506
4Veterans Affairs Medical Center, Cincinnati, OH 45221-0506
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Ana Franco-Villanueva
1Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45237-0506
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Rachel D. Moloney
1Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45237-0506
4Veterans Affairs Medical Center, Cincinnati, OH 45221-0506
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James P. Herman
1Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45237-0506
2Neuroscience Graduate Program, University of Cincinnati, Cincinnati, OH 45237-0506
4Veterans Affairs Medical Center, Cincinnati, OH 45221-0506
5Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH 45237-0506
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eneuro: 7 (5)
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September/October 2020
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Chemogenetic Inhibition of Infralimbic Prefrontal Cortex GABAergic Parvalbumin Interneurons Attenuates the Impact of Chronic Stress in Male Mice
Nawshaba Nawreen, Evelin M. Cotella, Rachel Morano, Parinaz Mahbod, Khushali S. Dalal, Maureen Fitzgerald, Susan Martelle, Benjamin A. Packard, Ana Franco-Villanueva, Rachel D. Moloney, James P. Herman
eNeuro 14 October 2020, 7 (5) ENEURO.0423-19.2020; DOI: 10.1523/ENEURO.0423-19.2020

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Chemogenetic Inhibition of Infralimbic Prefrontal Cortex GABAergic Parvalbumin Interneurons Attenuates the Impact of Chronic Stress in Male Mice
Nawshaba Nawreen, Evelin M. Cotella, Rachel Morano, Parinaz Mahbod, Khushali S. Dalal, Maureen Fitzgerald, Susan Martelle, Benjamin A. Packard, Ana Franco-Villanueva, Rachel D. Moloney, James P. Herman
eNeuro 14 October 2020, 7 (5) ENEURO.0423-19.2020; DOI: 10.1523/ENEURO.0423-19.2020
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Keywords

  • DREADDs
  • GABA
  • interneurons
  • parvalbumin
  • prefrontal cortex
  • stress coping

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