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Research ArticleResearch Article: Confirmation, Development

Grp94 Regulates the Recruitment of Aneural AChR Clusters for the Assembly of Postsynaptic Specializations by Modulating ADF/Cofilin Activity and Turnover

Zora Chui-Kuen Chan, Linyan Deng and Chi Wai Lee
eNeuro 3 August 2020, 7 (5) ENEURO.0025-20.2020; DOI: https://doi.org/10.1523/ENEURO.0025-20.2020
Zora Chui-Kuen Chan
School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
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Linyan Deng
School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
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Chi Wai Lee
School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0025-20.2020
PubMed 
32747457
Published By 
Society for Neuroscience
History 
  • Received January 26, 2020
  • Revision received July 27, 2020
  • Accepted July 27, 2020
  • Published online August 3, 2020.
Copyright & Usage 
Copyright © 2020 Chan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Zora Chui-Kuen Chan*,
  2. Linyan Deng* and
  3. Chi Wai Lee
  1. School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
  1. Correspondence should be addressed to Chi Wai Lee at chiwai.lee{at}hku.hk.
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Author contributions

  1. Author contributions: C.W.L. designed research; Z.C.-K.C., L.D., and C.W.L. performed research; C.W.L. contributed unpublished reagents/analytic tools; Z.C.-K.C., L.D., and C.W.L. analyzed data; C.W.L. wrote the paper.

  2. ↵*Z.C.-K.C. and L.D. contributed equally to this work.

Disclosures

  • The authors declare no competing financial interests.

  • This work was partly supported by the Early Career Grant 27102316 and General Research Fund Grants 17100718 and 17100219 from the Research Grants Council of Hong Kong, the Health and Medical Research Fund Grant 04151086 from the Food and Health Bureau of Hong Kong, and Seed Fund Programme for Basic Research from The University of Hong Kong Grants 201601159003, 201711159098, and 201811159078 (to C.W.L.).

Funding

  • Research Grants Council, University Grants Committee (RGC, UGC)

    27102316; 17100718; 17100219
  • FHB | Health and Medical Research Fund (HMRF)

    04151086

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  • You are viewing the most recent version of this article.
  • previous version (August 03, 2020).

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Aug 20203420143
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eneuro: 7 (5)
eNeuro
Vol. 7, Issue 5
September/October 2020
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Grp94 Regulates the Recruitment of Aneural AChR Clusters for the Assembly of Postsynaptic Specializations by Modulating ADF/Cofilin Activity and Turnover
Zora Chui-Kuen Chan, Linyan Deng, Chi Wai Lee
eNeuro 3 August 2020, 7 (5) ENEURO.0025-20.2020; DOI: 10.1523/ENEURO.0025-20.2020

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Grp94 Regulates the Recruitment of Aneural AChR Clusters for the Assembly of Postsynaptic Specializations by Modulating ADF/Cofilin Activity and Turnover
Zora Chui-Kuen Chan, Linyan Deng, Chi Wai Lee
eNeuro 3 August 2020, 7 (5) ENEURO.0025-20.2020; DOI: 10.1523/ENEURO.0025-20.2020
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Keywords

  • acetylcholine receptor
  • ADF/cofilin
  • Grp94
  • heat shock protein
  • neuromuscular junction
  • temperature stress

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