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Research ArticleResearch Article: New Research, Cognition and Behavior

Sex Differences in Maturation and Attrition of Adult Neurogenesis in the Hippocampus

Shunya Yagi, Jared E.J. Splinter, Daria Tai, Sarah Wong, Yanhua Wen and Liisa A.M. Galea
eNeuro 25 June 2020, 7 (4) ENEURO.0468-19.2020; https://doi.org/10.1523/ENEURO.0468-19.2020
Shunya Yagi
1Graduate Program in Neuroscience, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
4Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
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Jared E.J. Splinter
3Department of Physics and Astronomy, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
4Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
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Daria Tai
2Department of Psychology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
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Sarah Wong
2Department of Psychology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
4Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
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Yanhua Wen
2Department of Psychology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
4Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
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Liisa A.M. Galea
1Graduate Program in Neuroscience, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
2Department of Psychology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
4Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0468-19.2020
PubMed 
32586842
Published By 
Society for Neuroscience
History 
  • Received November 11, 2019
  • Revision received June 15, 2020
  • Accepted June 18, 2020
  • Published online June 25, 2020.
Copyright & Usage 
Copyright © 2020 Yagi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Shunya Yagi1,4,
  2. Jared E.J. Splinter3,4,
  3. Daria Tai2,
  4. Sarah Wong2,4,
  5. Yanhua Wen2,4 and
  6. Liisa A.M. Galea1,2,4
  1. 1Graduate Program in Neuroscience, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
  2. 2Department of Psychology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
  3. 3Department of Physics and Astronomy, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
  4. 4Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada
  1. Correspondence should be addressed to Liisa A. M. Galea at liisa.galea{at}ubc.ca.
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Author contributions

  1. Author contributions: S.Y. and L.A.M.G. designed research; S.Y., J.E.J.S., D.T., S.W., and Y.W. performed research; S.Y., J.E.J.S., Y.W., and L.A.M.G. analyzed data; S.Y. and L.A.M.G. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the Natural Sciences and Engineering Research Council (NSERC) Discovery Grant RGPIN-2018–04301 (to L.A.M.G.) and by a Izaak Walton Killam Memorial Pre-Doctoral Fellowship (S.Y.).

Funding

  • Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (NSERC)

    RGPIN-2018-04301
  • Killam Trusts (Killam)

Other Version

  • You are viewing the most recent version of this article.
  • previous version (June 25, 2020).

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Jun 2020151068
Jul 2020671681257
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Total 20251331522405
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Total 202688827136
Total156083282584
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eneuro: 7 (4)
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July/August 2020
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Sex Differences in Maturation and Attrition of Adult Neurogenesis in the Hippocampus
Shunya Yagi, Jared E.J. Splinter, Daria Tai, Sarah Wong, Yanhua Wen, Liisa A.M. Galea
eNeuro 25 June 2020, 7 (4) ENEURO.0468-19.2020; DOI: 10.1523/ENEURO.0468-19.2020

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Sex Differences in Maturation and Attrition of Adult Neurogenesis in the Hippocampus
Shunya Yagi, Jared E.J. Splinter, Daria Tai, Sarah Wong, Yanhua Wen, Liisa A.M. Galea
eNeuro 25 June 2020, 7 (4) ENEURO.0468-19.2020; DOI: 10.1523/ENEURO.0468-19.2020
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Keywords

  • BrdU
  • dentate gyrus
  • doublecortin
  • KI67
  • cell proliferation
  • cell survival
  • Sox2

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