Extended Data Figure 1-2
Comparison of fold changes in neurospheres following stimulation with and without Wnt inhibitor (sFRP2). A, sFRP2 blocked the vast majority of neurosphere growth in the stim-off cultures as predicted with a 16-fold decrease of stem cells and (B) a 17-fold decrease in stim-on conditions (****p < 0.0001). C, Blocking symmetric division does not inhibit the increase in neurospheres following electrical stimulation; n = 3 independent experiments, two-tailed unpaired t test, p = 0.3. Download Figure 1-2, TIF file.