Article Figures & Data
Figures
- Figure 1.
Bilateral inactivation of dmPFC, but not vmPFC, reduces the total number of nose pokes. A, There was a significant increase in total number of nose pokes and when the dorsal mPFC was bilaterally inactivated. B, In contrast, vmPFC inactivation did not affect nose poking. aCSF, control infusion; BM, baclofen and muscimol; *p < 0.05 (Adapted from Figure 1 in Caballero et al., 2019).
- Figure 2.
Bilateral inactivation of dmPFC, but not vmPFC, reduces the total number of nose pokes during late extinction. Rats were trained on FR1; bilateral infusions were only administered during late extinction. A, Inactivation of dmPFC during late extinction decreased nose pokes. B, There was no effect of vmPFC inactivation for number of nose pokes during late extinction. The extinction condition refers to behavior on the last day of extinction before testing with aCSF or BM occurred. aCSF, control infusion; BM, baclofen and muscimol; *p < 0.05 (Adapted from Figure 2 in Caballero et al., 2019).
- Figure 3.
Bilateral inactivation of vmPFC reduces the total number of nose pokes during reinstatement, whereas no effect was found for dmPFC bilateral inactivation. Reinstatement rats were trained on FR1; bilateral infusions were only administered during reinstatement. There was a significant increase in nose pokes on aCSF reinstatement infusion day compared with last day of extinction. A, Bilateral inactivation of dmPFC did not significantly affect nose pokes. B, Bilateral vmPFC inactivation significantly decreased total number of nose pokes. aCSF, control infusion; BM, baclofen and muscimol; *p < 0.05 (Adapted from Figure 3 in Caballero et al., 2019).
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