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Research ArticleResearch Article: New Research, Neuronal Excitability

Chemogenetic Suppression of GnRH Neurons during Pubertal Development Can Alter Adult GnRH Neuron Firing Rate and Reproductive Parameters in Female Mice

Eden A. Dulka, R. Anthony DeFazio and Suzanne M. Moenter
eNeuro 8 June 2020, 7 (3) ENEURO.0223-20.2020; https://doi.org/10.1523/ENEURO.0223-20.2020
Eden A. Dulka
1Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109
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R. Anthony DeFazio
1Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109
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Suzanne M. Moenter
1Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109
2Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109
3Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI 48109
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0223-20.2020
PubMed 
32513661
Published By 
Society for Neuroscience
History 
  • Received May 26, 2020
  • Accepted May 28, 2020
  • Published online June 8, 2020.
Copyright & Usage 
Copyright © 2020 Dulka et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Eden A. Dulka1,
  2. R. Anthony DeFazio1 and
  3. Suzanne M. Moenter1,2,3
  1. 1Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109
  2. 2Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109
  3. 3Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI 48109
  1. Correspondence should be addressed to Suzanne M. Moenter at smoenter{at}umich.edu
View Full Text

Author contributions

  1. Author contributions: E.A.D. and S.M.M. designed research; E.A.D. and R.A.D. performed research; E.A.D. and R.A.D. analyzed data; E.A.D., R.A.D., and S.M.M. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health and Human Development Grant P50 HD28934 (to S.M.M.) and a National Science Foundation Graduate Research Program Fellowship.

Funding

  • HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    P50 HD28934
  • National Science Foundation (NSF)

    Graduate Research Program Fellowship

Other Version

  • You are viewing the most recent version of this article.
  • previous version (June 08, 2020).

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Article usage: June 2020 to June 2025

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Jun 2020620208180
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Total 202537315110
Total126335871358
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Chemogenetic Suppression of GnRH Neurons during Pubertal Development Can Alter Adult GnRH Neuron Firing Rate and Reproductive Parameters in Female Mice
Eden A. Dulka, R. Anthony DeFazio, Suzanne M. Moenter
eNeuro 8 June 2020, 7 (3) ENEURO.0223-20.2020; DOI: 10.1523/ENEURO.0223-20.2020

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Chemogenetic Suppression of GnRH Neurons during Pubertal Development Can Alter Adult GnRH Neuron Firing Rate and Reproductive Parameters in Female Mice
Eden A. Dulka, R. Anthony DeFazio, Suzanne M. Moenter
eNeuro 8 June 2020, 7 (3) ENEURO.0223-20.2020; DOI: 10.1523/ENEURO.0223-20.2020
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Keywords

  • chemogenetic
  • development
  • infertility
  • Neural Activity
  • neuroendocrine

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