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Research ArticleResearch Article: New Research, Development

Increased Tau Expression Correlates with Neuronal Maturation in the Developing Human Cerebral Cortex

Kimberly L. Fiock, Martin E. Smalley, John F. Crary, Anca M. Pasca and Marco M. Hefti
eNeuro 11 May 2020, 7 (3) ENEURO.0058-20.2020; https://doi.org/10.1523/ENEURO.0058-20.2020
Kimberly L. Fiock
1Department of Pathology, University of Iowa, Iowa City, IA 52242
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Martin E. Smalley
1Department of Pathology, University of Iowa, Iowa City, IA 52242
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John F. Crary
2Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY
4Friedmann Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
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Anca M. Pasca
5Department of Pediatrics, Stanford University, Palo Alto, CA 94305
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Marco M. Hefti
1Department of Pathology, University of Iowa, Iowa City, IA 52242
6Iowa Neuroscience Institute, University of Iowa, Iowa City, IA 52242
7Interdisciplinary Neuroscience Graduate Program, University of Iowa, Iowa City, IA 52242
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0058-20.2020
PubMed 
32393582
Published By 
Society for Neuroscience
History 
  • Received February 4, 2020
  • Revision received April 2, 2020
  • Accepted May 4, 2020
  • Published online May 11, 2020.
Copyright & Usage 
Copyright © 2020 Fiock et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Kimberly L. Fiock1,
  2. Martin E. Smalley1,
  3. John F. Crary2,3,4,
  4. Anca M. Pasca5 and
  5. Marco M. Hefti1,6,7
  1. 1Department of Pathology, University of Iowa, Iowa City, IA 52242
  2. 2Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  3. 3Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY
  4. 4Friedmann Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  5. 5Department of Pediatrics, Stanford University, Palo Alto, CA 94305
  6. 6Iowa Neuroscience Institute, University of Iowa, Iowa City, IA 52242
  7. 7Interdisciplinary Neuroscience Graduate Program, University of Iowa, Iowa City, IA 52242
  1. Correspondence should be addressed to Marco M. Hefti at marco-hefti{at}uiowa.edu.
View Full Text

Author contributions

  1. Author contributions: K.L.F. and M.M.H. designed research; K.L.F., M.E.S., and A.M.P. performed research; K.L.F., J.F.C., and M.M.H. analyzed data; K.L.F., J.F.C., A.M.P., and M.M.H. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported in part by National Institutes of Health Grants UL1TR002537 and K23NS109284 (to M.M.H.) and the Williams-Cannon Foundation (M.M.H.).

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    UL1TR002537; K23NS109284
  • Williams Cannon Foundation

Other Version

  • You are viewing the most recent version of this article.
  • previous version (May 11, 2020).

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Article usage: May 2020 to January 2026

AbstractFullPdf
May 2020725102337
Jun 2020553376142
Jul 20205238892
Aug 20203017261
Sep 20202722091
Oct 20201421277
Nov 20201418856
Dec 20201015649
Total 202014251814905
Jan 2021315260
Feb 2021414357
Mar 2021617850
Apr 2021115041
May 2021112136
Jun 2021515350
Jul 202159930
Aug 2021110635
Sep 2021214947
Oct 2021613072
Nov 2021410437
Dec 2021011039
Total 2021381595554
Jan 2022610032
Feb 202249755
Mar 202239537
Apr 2022510556
May 202249846
Jun 2022212039
Jul 202219136
Aug 202216523
Sep 202214858
Oct 202235425
Nov 202235827
Dec 202234513
Total 202236976447
Jan 202336026
Feb 202305917
Mar 202347023
Apr 202307923
May 202305513
Jun 202316239
Jul 202376921
Aug 2023117544
Sep 202367817
Oct 2023129131
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Total 202354869313
Jan 2024197620
Feb 202446626
Mar 202486220
Apr 2024177926
May 202497427
Jun 2024117923
Jul 2024106922
Aug 2024146927
Sep 2024117335
Oct 2024157437
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Dec 202457022
Total 2024134857313
Jan 2025127522
Feb 2025147622
Mar 202569538
Apr 202577421
May 2025147027
Jun 2025138416
Jul 2025228738
Aug 202578639
Sep 20252111447
Oct 20251510935
Nov 20251315837
Dec 20251514440
Total 20251591172382
Jan 202646723
Total 202646723
Total185073502937
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Increased Tau Expression Correlates with Neuronal Maturation in the Developing Human Cerebral Cortex
Kimberly L. Fiock, Martin E. Smalley, John F. Crary, Anca M. Pasca, Marco M. Hefti
eNeuro 11 May 2020, 7 (3) ENEURO.0058-20.2020; DOI: 10.1523/ENEURO.0058-20.2020

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Increased Tau Expression Correlates with Neuronal Maturation in the Developing Human Cerebral Cortex
Kimberly L. Fiock, Martin E. Smalley, John F. Crary, Anca M. Pasca, Marco M. Hefti
eNeuro 11 May 2020, 7 (3) ENEURO.0058-20.2020; DOI: 10.1523/ENEURO.0058-20.2020
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Keywords

  • Alzheimer’s disease
  • fetal
  • neurodegeneration
  • neurodevelopment
  • organoid
  • tau

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