eneuro: 7 (3)

Month/Month; Volume 7,Issue 3

Articles

Hypoxia-Inducible Factor 1α (HIF-1α) Counteracts the Acute Death of Cells Transplanted into the Injured Spinal Cord
Brian T. David, Jessica J. Curtin, David C. Goldberg, Kerri Scorpio, Veena Kandaswamy and Caitlin E. Hill

eNeuro 5 September 2019, 7 (3) ENEURO.0092-19.2019; DOI: https://doi.org/10.1523/ENEURO.0092-19.2019

Erratum/Corrigendum

Erratum: Vargas Abonce et al., Homeoprotein Neuroprotection of Embryonic Neuronal Cells
eNeuro 23 June 2020, 7 (3) ENEURO.0227-20.2020; DOI: https://doi.org/10.1523/ENEURO.0227-20.2020

Research Article: New Research

Early-Life m⁶A RNA Demethylation by Fat Mass and Obesity-Associated Protein (FTO) Influences Resilience or Vulnerability to Heat Stress Later in Life
Tatiana Kisliouk, Tali Rosenberg, Osher Ben-Nun, Mark Ruzal and Noam Meiri

eNeuro 17 June 2020, 7 (3) ENEURO.0549-19.2020; DOI: https://doi.org/10.1523/ENEURO.0549-19.2020
The Reuniens and Rhomboid Nuclei Are Required for Acquisition of Pavlovian Trace Fear Conditioning in Rats
Yu-Ju Lin, Ruei-Jen Chiou and Chun-hui Chang

eNeuro 11 June 2020, 7 (3) ENEURO.0106-20.2020; DOI: https://doi.org/10.1523/ENEURO.0106-20.2020
Chemogenetic Suppression of GnRH Neurons during Pubertal Development Can Alter Adult GnRH Neuron Firing Rate and Reproductive Parameters in Female Mice
Eden A. Dulka, R. Anthony DeFazio and Suzanne M. Moenter

eNeuro 8 June 2020, 7 (3) ENEURO.0223-20.2020; DOI: https://doi.org/10.1523/ENEURO.0223-20.2020
Synaptic Connections of Aromatase Circuits in the Medial Amygdala Are Sex Specific
Addison Billing, Marcelo Henrique Correia, Diane A. Kelly, Geng-Lin Li and Joseph F. Bergan

eNeuro 29 May 2020, 7 (3) ENEURO.0489-19.2020; DOI: https://doi.org/10.1523/ENEURO.0489-19.2020
HIV Tat Protein Selectively Impairs CB₁ Receptor-Mediated Presynaptic Inhibition at Excitatory But Not Inhibitory Synapses
Mariah M. Wu and Stanley A. Thayer

eNeuro 29 May 2020, 7 (3) ENEURO.0119-20.2020; DOI: https://doi.org/10.1523/ENEURO.0119-20.2020
Brief Electrical Stimulation Triggers an Effective Regeneration of Leech CNS
Sharon Cohen, Alon Richter-Levin and Orit Shefi

eNeuro 29 May 2020, 7 (3) ENEURO.0030-19.2020; DOI: https://doi.org/10.1523/ENEURO.0030-19.2020
Circuit-Specific Dendritic Development in the Piriform Cortex
Laura Moreno-Velasquez, Hung Lo, Stephen Lenzi, Malte Kaehne, Jörg Breustedt, Dietmar Schmitz, Sten Rüdiger and Friedrich W. Johenning

eNeuro 26 May 2020, 7 (3) ENEURO.0083-20.2020; DOI: https://doi.org/10.1523/ENEURO.0083-20.2020
Distinct Region- and Time-Dependent Functional Cortical Adaptations in C57BL/6J Mice after Short and Prolonged Alcohol Drinking
Reginald Cannady, Sudarat Nimitvilai-Roberts, Sarah D. Jennings, John J. Woodward and Patrick J. Mulholland

eNeuro 21 May 2020, 7 (3) ENEURO.0077-20.2020; DOI: https://doi.org/10.1523/ENEURO.0077-20.2020
In Vivo Diffusion Tensor Imaging in Acute and Subacute Phases of Mild Traumatic Brain Injury in Rats
Isabel San Martín Molina, Raimo A. Salo, Ali Abdollahzadeh, Jussi Tohka, Olli Gröhn and Alejandra Sierra

eNeuro 18 May 2020, 7 (3) ENEURO.0476-19.2020; DOI: https://doi.org/10.1523/ENEURO.0476-19.2020
Differential Rapid Plasticity in Auditory and Visual Responses in the Primarily Multisensory Orbitofrontal Cortex
Sudha Sharma and Sharba Bandyopadhyay

eNeuro 18 May 2020, 7 (3) ENEURO.0061-20.2020; DOI: https://doi.org/10.1523/ENEURO.0061-20.2020
Many Paths to the Same Goal: Balancing Exploration and Exploitation during Probabilistic Route Planning
Brian J. Jackson, Gusti Lulu Fatima, Sujean Oh and David H. Gire

eNeuro 15 May 2020, 7 (3) ENEURO.0536-19.2020; DOI: https://doi.org/10.1523/ENEURO.0536-19.2020
Ablation of TRPV1+ Afferent Terminals by Capsaicin Mediates Long-Lasting Analgesia for Trigeminal Neuropathic Pain
Sheng Wang, Chao Bian, Jiale Yang, Vipin Arora, Yiwei Gao, Feng Wei and Man-Kyo Chung

eNeuro 13 May 2020, 7 (3) ENEURO.0118-20.2020; DOI: https://doi.org/10.1523/ENEURO.0118-20.2020
How Do We Segment Text? Two-Stage Chunking Operation in Reading
Jinbiao Yang (杨金骉), Qing Cai (蔡清) and Xing Tian (田兴)

eNeuro 11 May 2020, 7 (3) ENEURO.0425-19.2020; DOI: https://doi.org/10.1523/ENEURO.0425-19.2020
Role of Synaptic Inhibition in the Coupling of the Respiratory Rhythms that Underlie Eupnea and Sigh Behaviors
Daniel S. Borrus, Cameron J. Grover, Gregory D. Conradi Smith and Christopher A. Del Negro

eNeuro 11 May 2020, 7 (3) ENEURO.0302-19.2020; DOI: https://doi.org/10.1523/ENEURO.0302-19.2020
Vitamin D Supplementation Rescues Aberrant NF-κB Pathway Activation and Partially Ameliorates Rett Syndrome Phenotypes in Mecp2 Mutant Mice
Mayara C. Ribeiro, Seth M. Moore, Noriyuki Kishi, Jeffrey D. Macklis and Jessica L. MacDonald

eNeuro 11 May 2020, 7 (3) ENEURO.0167-20.2020; DOI: https://doi.org/10.1523/ENEURO.0167-20.2020
Increased Tau Expression Correlates with Neuronal Maturation in the Developing Human Cerebral Cortex
Kimberly L. Fiock, Martin E. Smalley, John F. Crary, Anca M. Pasca and Marco M. Hefti

eNeuro 11 May 2020, 7 (3) ENEURO.0058-20.2020; DOI: https://doi.org/10.1523/ENEURO.0058-20.2020
Chronic α-Synuclein Accumulation in Rat Hippocampus Induces Lewy Bodies Formation and Specific Cognitive Impairments
Danielle Walu Kasongo, Gioacchino de Leo, Nunzio Vicario, Giampiero Leanza and Giuseppe Legname

eNeuro 11 May 2020, 7 (3) ENEURO.0009-20.2020; DOI: https://doi.org/10.1523/ENEURO.0009-20.2020
Unanticipated Stressful and Rewarding Experiences Engage the Same Prefrontal Cortex and Ventral Tegmental Area Neuronal Populations
Alberto Del Arco, Junchol Park and Bita Moghaddam

eNeuro 8 May 2020, 7 (3) ENEURO.0029-20.2020; DOI: https://doi.org/10.1523/ENEURO.0029-20.2020
Dissociable Behavioral and Neural Correlates for Target-Changing and Conforming Behaviors in Interpersonal Aggression
Kyosuke Takami and Masahiko Haruno

eNeuro 7 May 2020, 7 (3) ENEURO.0273-19.2020; DOI: https://doi.org/10.1523/ENEURO.0273-19.2020
RPE Cells Engulf Microvesicles Secreted by Degenerating Rod Photoreceptors
Philip Ropelewski and Yoshikazu Imanishi

eNeuro 6 May 2020, 7 (3) ENEURO.0507-19.2020; DOI: https://doi.org/10.1523/ENEURO.0507-19.2020
Differential Stability of miR-9-5p and miR-9-3p in the Brain Is Determined by Their Unique Cis- and Trans-Acting Elements
C.K. Kim, A. Asimes, M. Zhang, B.T. Son, J.A. Kirk and T.R. Pak

eNeuro 6 May 2020, 7 (3) ENEURO.0094-20.2020; DOI: https://doi.org/10.1523/ENEURO.0094-20.2020
Hippocampal Synaptic Dysfunction in a Mouse Model of Huntington Disease Is Not Alleviated by Ceftriaxone Treatment
Crystal M. Wilkie, Jocelyn R. Barnes, Cherry-Lynn M. Benson, Kyle J. Brymer, Firoozeh Nafar and Matthew P. Parsons

eNeuro 30 April 2020, 7 (3) ENEURO.0440-19.2020; DOI: https://doi.org/10.1523/ENEURO.0440-19.2020
ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors
Miguel Skirzewski, Marie E. Cronin, Ricardo Murphy, Wambura Fobbs, Alexxai V. Kravitz and Andres Buonanno

eNeuro 30 April 2020, 7 (3) ENEURO.0395-19.2020; DOI: https://doi.org/10.1523/ENEURO.0395-19.2020
Peripheral Nerve Single-Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth
Jeremy S. Toma, Konstantina Karamboulas, Matthew J. Carr, Adelaida Kolaj, Scott A. Yuzwa, Neemat Mahmud, Mekayla A. Storer, David R. Kaplan and Freda D. Miller

eNeuro 29 April 2020, 7 (3) ENEURO.0066-20.2020; DOI: https://doi.org/10.1523/ENEURO.0066-20.2020
Effect of Circuit Structure on Odor Representation in the Insect Olfactory System
Adithya Rajagopalan and Collins Assisi

eNeuro 28 April 2020, 7 (3) ENEURO.0130-19.2020; DOI: https://doi.org/10.1523/ENEURO.0130-19.2020
Dopamine and Risky Decision-Making in Gambling Disorder
Jan Peters, Taylor Vega, Dawn Weinstein, Jennifer Mitchell and Andrew Kayser

eNeuro 27 April 2020, 7 (3) ENEURO.0461-19.2020; DOI: https://doi.org/10.1523/ENEURO.0461-19.2020
Depletion of the Microbiome Alters the Recruitment of Neuronal Ensembles of Oxycodone Intoxication and Withdrawal
Sierra Simpson, Adam Kimbrough, Brent Boomhower, Rio McLellan, Marcella Hughes, Kokila Shankar, Giordano de Guglielmo and Olivier George

eNeuro 27 April 2020, 7 (3) ENEURO.0312-19.2020; DOI: https://doi.org/10.1523/ENEURO.0312-19.2020
Neural Differentiation is Moderated by Age in Scene-Selective, But Not Face-Selective, Cortical Regions
Sabina Srokova, Paul F. Hill, Joshua D. Koen, Danielle R. King and Michael D. Rugg

eNeuro 27 April 2020, 7 (3) ENEURO.0142-20.2020; DOI: https://doi.org/10.1523/ENEURO.0142-20.2020
Response-Related Signals Increase Confidence But Not Metacognitive Performance
Elisa Filevich, Christina Koß and Nathan Faivre

eNeuro 23 April 2020, 7 (3) ENEURO.0326-19.2020; DOI: https://doi.org/10.1523/ENEURO.0326-19.2020
Action Video Gaming Does Not Influence Short-Term Ocular Dominance Plasticity in Visually Normal Adults
Xiaoxin Chen, Shijia Chen, Deying Kong, Junhan Wei, Yu Mao, Wenman Lin, Yiya Chen, Zhimo Yao, Seung Hyun Min, Fan Lu, Jia Qu, Robert F. Hess and Jiawei Zhou

eNeuro 28 April 2020, 7 (3) ENEURO.0006-20.2020; DOI: https://doi.org/10.1523/ENEURO.0006-20.2020
GAD2 Expression Defines a Class of Excitatory Lateral Habenula Neurons in Mice that Project to the Raphe and Pontine Tegmentum
Lely A. Quina, Andrew Walker, Glenn Morton, Victor Han and Eric. E. Turner

eNeuro 24 April 2020, 7 (3) ENEURO.0527-19.2020; DOI: https://doi.org/10.1523/ENEURO.0527-19.2020
Lateralized Expression of Cortical Perineuronal Nets during Maternal Experience is Dependent on MECP2
Billy Y. B. Lau, Dana E. Layo, Brett Emery, Matthew Everett, Anushree Kumar, Parker Stevenson, Kristopher G. Reynolds, Andrew Cherosky, Sarah-Anne H. Bowyer, Sarah Roth, Delaney G. Fisher, Rachel P. McCord and Keerthi Krishnan

eNeuro 24 April 2020, 7 (3) ENEURO.0500-19.2020; DOI: https://doi.org/10.1523/ENEURO.0500-19.2020
Age-Related Changes in Synaptic Plasticity Associated with Mossy Fiber Terminal Integration during Adult Neurogenesis
Karl D. Murray, Xiao-Bo Liu, Anna N. King, Julie D. Luu and Hwai-Jong Cheng

eNeuro 24 April 2020, 7 (3) ENEURO.0030-20.2020; DOI: https://doi.org/10.1523/ENEURO.0030-20.2020
Rapid Adaptation to Changing Mechanical Load by Ordered Recruitment of Identified Motor Neurons
Jeffrey P. Gill and Hillel J. Chiel

eNeuro 24 April 2020, 7 (3) ENEURO.0016-20.2020; DOI: https://doi.org/10.1523/ENEURO.0016-20.2020
Aging But Not Age-Related Hearing Loss Dominates the Decrease of Parvalbumin Immunoreactivity in the Primary Auditory Cortex of Mice
Meike M. Rogalla and K. Jannis Hildebrandt

eNeuro 23 April 2020, 7 (3) ENEURO.0511-19.2020; DOI: https://doi.org/10.1523/ENEURO.0511-19.2020
First-Person Virtual Embodiment Modulates the Cortical Network that Encodes the Bodily Self and Its Surrounding Space during the Experience of Domestic Violence
Aline W. de Borst, Maria V. Sanchez-Vives, Mel Slater and Beatrice de Gelder

eNeuro 20 April 2020, 7 (3) ENEURO.0263-19.2019; DOI: https://doi.org/10.1523/ENEURO.0263-19.2019
Early Restoration of Shank3 Expression in Shank3 Knock-Out Mice Prevents Core ASD-Like Behavioral Phenotypes
Thomas C. Jaramillo, Zhong Xuan, Jeremy M. Reimers, Christine O. Escamilla, Shunan Liu and Craig M. Powell

eNeuro 23 April 2020, 7 (3) ENEURO.0332-19.2020; DOI: https://doi.org/10.1523/ENEURO.0332-19.2020
Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release
Rémi Opsomer, Sabrina Contino, Florian Perrin, Roberta Gualdani, Bernadette Tasiaux, Pierre Doyen, Maxime Vergouts, Céline Vrancx, Anna Doshina, Nathalie Pierrot, Jean-Noël Octave, Philippe Gailly, Serena Stanga and Pascal Kienlen-Campard

eNeuro 23 April 2020, 7 (3) ENEURO.0322-19.2020; DOI: https://doi.org/10.1523/ENEURO.0322-19.2020
Propofol Modulates Early Memory Consolidation in Humans
Daa Un Moon, Nazli Esfahani-Bayerl, Carsten Finke, Daniel J. Salchow, Mario Menk, Simon Bayerl, Richard Kempter and Christoph J. Ploner

eNeuro 15 April 2020, 7 (3) ENEURO.0537-19.2020; DOI: https://doi.org/10.1523/ENEURO.0537-19.2020
Topological Data Analysis Reveals Robust Alterations in the Whole-Brain and Frontal Lobe Functional Connectomes in Attention-Deficit/Hyperactivity Disorder
Zeus Gracia-Tabuenca, Juan Carlos Díaz-Patiño, Isaac Arelio and Sarael Alcauter

eNeuro 21 April 2020, 7 (3) ENEURO.0543-19.2020; DOI: https://doi.org/10.1523/ENEURO.0543-19.2020
Dopamine D2-Like Receptors Modulate Intrinsic Properties and Synaptic Transmission of Parvalbumin Interneurons in the Mouse Primary Motor Cortex
Jérémy Cousineau, Léa Lescouzères, Anne Taupignon, Lorena Delgado-Zabalza, Emmanuel Valjent, Jérôme Baufreton and Morgane Le Bon-Jégo

eNeuro 22 April 2020, 7 (3) ENEURO.0081-20.2020; DOI: https://doi.org/10.1523/ENEURO.0081-20.2020
Neural Coding of Thermal Preferences in the Nematode Caenorhabditis elegans
Hironori J. Matsuyama and Ikue Mori

eNeuro 6 April 2020, 7 (3) ENEURO.0414-19.2020; DOI: https://doi.org/10.1523/ENEURO.0414-19.2020
Muscarinic-Dependent miR-182 and QR2 Expression Regulation in the Anterior Insula Enables Novel Taste Learning
Nathaniel L. Gould, Alina Elkobi, Efrat Edry, Jonathan Daume and Kobi Rosenblum

eNeuro 26 March 2020, 7 (3) ENEURO.0067-20.2020; DOI: https://doi.org/10.1523/ENEURO.0067-20.2020
Resting State BOLD Variability of the Posterior Medial Temporal Lobe Correlates with Cognitive Performance in Older Adults with and without Risk for Cognitive Decline
Tyler J. Good, Joshua Villafuerte, Jennifer D. Ryan, Cheryl L. Grady and Morgan D. Barense

eNeuro 19 March 2020, 7 (3) ENEURO.0290-19.2020; DOI: https://doi.org/10.1523/ENEURO.0290-19.2020
Familiarity Detection and Memory Consolidation in Cortical Assemblies
Xiaoyu Zhang, Fang-Chin Yeh, Han Ju, Yuheng Jiang, Gabriel Foo Wei Quan and Antonius M.J. VanDongen

eNeuro 2 March 2020, 7 (3) ENEURO.0006-19.2020; DOI: https://doi.org/10.1523/ENEURO.0006-19.2020

Research article: New Research

A HIF1a-Dependent Pro-Oxidant State Disrupts Synaptic Plasticity and Impairs Spatial Memory in Response to Intermittent Hypoxia
Alejandra Arias-Cavieres, Maggie A. Khuu, Chinwendu U. Nwakudu, Jasmine E. Barnard, Gokhan Dalgin and Alfredo J. Garcia

eNeuro 3 June 2020, 7 (3) ENEURO.0024-20.2020; DOI: https://doi.org/10.1523/ENEURO.0024-20.2020

Research Article: Confirmation

Human Face-Selective Cortex Does Not Distinguish between Members of a Racial Outgroup
Niv Reggev, Kirstan Brodie, Mina Cikara and Jason P. Mitchell

eNeuro 18 May 2020, 7 (3) ENEURO.0431-19.2020; DOI: https://doi.org/10.1523/ENEURO.0431-19.2020
A Single Intraventricular Injection of VEGF Leads to Long-Term Neurotrophic Effects in Axotomized Motoneurons
Paula M. Calvo, Rosa R. de la Cruz and Angel M. Pastor

eNeuro 5 May 2020, 7 (3) ENEURO.0467-19.2020; DOI: https://doi.org/10.1523/ENEURO.0467-19.2020
Behavioral Characterization of dmrt3a Mutant Zebrafish Reveals Crucial Aspects of Vertebrate Locomotion through Phenotypes Related to Acceleration
Ana del Pozo, Remy Manuel, Ana Belen Iglesias Gonzalez, Harmen Kornelis Koning, Judith Habicher, Hanqing Zhang, Amin Allalou, Klas Kullander and Henrik Boije

eNeuro 1 May 2020, 7 (3) ENEURO.0047-20.2020; DOI: https://doi.org/10.1523/ENEURO.0047-20.2020
Deficiency of Complement Component C1Q Prevents Cerebrovascular Damage and White Matter Loss in a Mouse Model of Chronic Obesity
Leah C. Graham, Heidi E. Kocalis, Ileana Soto and Gareth R. Howell

eNeuro 9 April 2020, 7 (3) ENEURO.0057-20.2020; DOI: https://doi.org/10.1523/ENEURO.0057-20.2020

Research Article: Methods/New Tools

Real-Time Selective Markerless Tracking of Forepaws of Head Fixed Mice Using Deep Neural Networks
Brandon J. Forys, Dongsheng Xiao, Pankaj Gupta and Timothy H. Murphy

eNeuro 14 May 2020, 7 (3) ENEURO.0096-20.2020; DOI: https://doi.org/10.1523/ENEURO.0096-20.2020
Targeting Morphine-Responsive Neurons: Generation of a Knock-In Mouse Line Expressing Cre Recombinase from the Mu-Opioid Receptor Gene Locus
Julie Bailly, Natalie Del Rossi, Léonie Runtz, Jing-Jing Li, DaWoon Park, Grégory Scherrer, Arnaud Tanti, Marie-Christine Birling, Emmanuel Darcq and Brigitte L. Kieffer

eNeuro 7 May 2020, 7 (3) ENEURO.0433-19.2020; DOI: https://doi.org/10.1523/ENEURO.0433-19.2020
An Intersectional Viral-Genetic Method for Fluorescent Tracing of Axon Collaterals Reveals Details of Noradrenergic Locus Coeruleus Structure
Nicholas W. Plummer, Daniel J. Chandler, Jeanne M. Powell, Erica L. Scappini, Barry D. Waterhouse and Patricia Jensen

eNeuro 30 April 2020, 7 (3) ENEURO.0010-20.2020; DOI: https://doi.org/10.1523/ENEURO.0010-20.2020
Voltage Imaging of Cortical Oscillations in Layer 1 with Two-Photon Microscopy
Neil Dalphin, Kevin Dorgans, Eugene Khaskin and Bernd Kuhn

eNeuro 22 April 2020, 7 (3) ENEURO.0274-19.2020; DOI: https://doi.org/10.1523/ENEURO.0274-19.2020

Theory/New Concepts

A Model for Structured Information Representation in Neural Networks of the Brain
Michael G. Müller, Christos H. Papadimitriou, Wolfgang Maass and Robert Legenstein

eNeuro 7 May 2020, 7 (3) ENEURO.0533-19.2020; DOI: https://doi.org/10.1523/ENEURO.0533-19.2020

Open Source Tools and Methods

neurotic: Neuroscience Tool for Interactive Characterization
Jeffrey P. Gill, Samuel Garcia, Lena H. Ting, Mengnan Wu and Hillel J. Chiel

eNeuro 24 April 2020, 7 (3) ENEURO.0085-20.2020; DOI: https://doi.org/10.1523/ENEURO.0085-20.2020
Rodent Arena Tracker (RAT): A Machine Vision Rodent Tracking Camera and Closed Loop Control System
Jonathan Krynitsky, Alex A. Legaria, Julia J. Pai, Marcial Garmendia-Cedillos, Ghadi Salem, Tom Pohida and Alexxai V. Kravitz

eNeuro 13 April 2020, 7 (3) ENEURO.0485-19.2020; DOI: https://doi.org/10.1523/ENEURO.0485-19.2020
An Open Source Automated Bar Test for Measuring Catalepsy in Rats
Karling R. Luciani, Jude A. Frie and Jibran Y. Khokhar

eNeuro 20 March 2020, 7 (3) ENEURO.0488-19.2020; DOI: https://doi.org/10.1523/ENEURO.0488-19.2020

Research Article: Theory/New Concepts

Shunting Inhibition Improves Synchronization in Heterogeneous Inhibitory Interneuronal Networks with Type 1 Excitability Whereas Hyperpolarizing Inhibition Is Better for Type 2 Excitability
Ruben A. Tikidji-Hamburyan and Carmen C. Canavier

eNeuro 20 March 2020, 7 (3) ENEURO.0464-19.2020; DOI: https://doi.org/10.1523/ENEURO.0464-19.2020

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Table of Contents

Articles

Erratum/Corrigendum

Research Article: New Research

Research article: New Research

Research Article: Confirmation

Research Article: Methods/New Tools

Theory/New Concepts

Open Source Tools and Methods

Research Article: Theory/New Concepts

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