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Research ArticleResearch Article: New Research, Development

Components of Endocannabinoid Signaling System Are Expressed in the Perinatal Mouse Cerebellum and Required for Its Normal Development

Luis Ricardo Martinez, Kylie Caroline Black, Brynna Tellas Webb, Alexandria Bell, Shawyon Kevin Baygani, Tristen Jay Mier, Luis Dominguez, Ken Mackie and Anna Kalinovsky
eNeuro 16 March 2020, 7 (2) ENEURO.0471-19.2020; https://doi.org/10.1523/ENEURO.0471-19.2020
Luis Ricardo Martinez
1The Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences, Indiana University, Bloomington, 47405 IN
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  • ORCID record for Luis Ricardo Martinez
Kylie Caroline Black
1The Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences, Indiana University, Bloomington, 47405 IN
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  • ORCID record for Kylie Caroline Black
Brynna Tellas Webb
1The Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences, Indiana University, Bloomington, 47405 IN
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Alexandria Bell
1The Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences, Indiana University, Bloomington, 47405 IN
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Shawyon Kevin Baygani
1The Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences, Indiana University, Bloomington, 47405 IN
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Tristen Jay Mier
1The Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences, Indiana University, Bloomington, 47405 IN
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  • ORCID record for Tristen Jay Mier
Luis Dominguez
1The Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences, Indiana University, Bloomington, 47405 IN
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Ken Mackie
1The Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences, Indiana University, Bloomington, 47405 IN
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Anna Kalinovsky
1The Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences, Indiana University, Bloomington, 47405 IN
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0471-19.2020
PubMed 
32179579
Published By 
Society for Neuroscience
History 
  • Received November 13, 2019
  • Revision received February 26, 2020
  • Accepted February 28, 2020
  • Published online March 16, 2020.
Copyright & Usage 
Copyright © 2020 Martinez et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Luis Ricardo Martinez1,
  2. Kylie Caroline Black1,
  3. Brynna Tellas Webb1,
  4. Alexandria Bell1,
  5. Shawyon Kevin Baygani1,
  6. Tristen Jay Mier1,
  7. Luis Dominguez1,
  8. Ken Mackie1 and
  9. Anna Kalinovsky1
  1. 1The Gill Center for Biomolecular Science, Program in Neuroscience, Department of Psychological and Brain Sciences, Indiana University, Bloomington, 47405 IN
  1. Correspondence should be addressed to Anna Kalinovsky at akalinov{at}iu.edu
View Full Text

Author contributions

  1. Author contributions: A.K. designed research; K.M. provided critical feedback and contributed reagents; L.R.M., K.C.B., B.T.W., A.B., S.K.B., T.J.M., L.D., and A.K. performed research; K.C.B., B.T.W., S.K.B., T.J.M., and A.K. analyzed data; L.R.M. and A.K. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the National Institute on Drug Abuse R21 Grant DA044000 and by a research fund from the Indiana University Department of Psychological and Brain Sciences.

Funding

  • HHS | NIH | National Institute on Drug Abuse (NIDA)

    DA044000

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  • previous version (March 16, 2020).

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Total83049451601
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eneuro: 7 (2)
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Components of Endocannabinoid Signaling System Are Expressed in the Perinatal Mouse Cerebellum and Required for Its Normal Development
Luis Ricardo Martinez, Kylie Caroline Black, Brynna Tellas Webb, Alexandria Bell, Shawyon Kevin Baygani, Tristen Jay Mier, Luis Dominguez, Ken Mackie, Anna Kalinovsky
eNeuro 16 March 2020, 7 (2) ENEURO.0471-19.2020; DOI: 10.1523/ENEURO.0471-19.2020

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Components of Endocannabinoid Signaling System Are Expressed in the Perinatal Mouse Cerebellum and Required for Its Normal Development
Luis Ricardo Martinez, Kylie Caroline Black, Brynna Tellas Webb, Alexandria Bell, Shawyon Kevin Baygani, Tristen Jay Mier, Luis Dominguez, Ken Mackie, Anna Kalinovsky
eNeuro 16 March 2020, 7 (2) ENEURO.0471-19.2020; DOI: 10.1523/ENEURO.0471-19.2020
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Keywords

  • ataxia
  • cannabinoid
  • CB1
  • cerebellum
  • coordination
  • development

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