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Research ArticleResearch Article: Theory/New Concepts, Development

Poor Concordance of Floxed Sequence Recombination in Single Neural Stem Cells: Implications for Cell Autonomous Studies

Tyler Joseph Dause and Elizabeth Diana Kirby
eNeuro 20 February 2020, 7 (2) ENEURO.0470-19.2020; https://doi.org/10.1523/ENEURO.0470-19.2020
Tyler Joseph Dause
1Deptartment of Psychology, The Ohio State University, Columbus, OH 43210
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Elizabeth Diana Kirby
1Deptartment of Psychology, The Ohio State University, Columbus, OH 43210
2Deptartment of Neuroscience, The Ohio State University, Columbus, OH 43210
3The Chronic Brain Injury Program, The Ohio State University, Columbus, OH 43210
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0470-19.2020
PubMed 
32079584
Published By 
Society for Neuroscience
History 
  • Received November 13, 2019
  • Revision received January 17, 2020
  • Accepted January 23, 2020
  • Published online February 20, 2020.
Copyright & Usage 
Copyright © 2020 Dause and Kirby This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Tyler Joseph Dause1 and
  2. Elizabeth Diana Kirby1,2,3
  1. 1Deptartment of Psychology, The Ohio State University, Columbus, OH 43210
  2. 2Deptartment of Neuroscience, The Ohio State University, Columbus, OH 43210
  3. 3The Chronic Brain Injury Program, The Ohio State University, Columbus, OH 43210
  1. Correspondence should be addressed to Elizabeth Diana Kirby at kirby.224{at}osu.edu.
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Author contributions

  1. Author contributions: T.J.D. and E.D.K. designed research; T.J.D. and E.D.K. performed research; T.J.D. and E.D.K. analyzed data; T.J.D. and E.D.K. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the National Science Foundation Grant IOS-1923094 (to E.D.K.).

Funding

  • National Science Foundation (NSF)

    IOS-1923094

Other Version

  • You are viewing the most recent version of this article.
  • previous version (February 20, 2020).

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Total109036251111
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eneuro: 7 (2)
eNeuro
Vol. 7, Issue 2
March/April 2020
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Poor Concordance of Floxed Sequence Recombination in Single Neural Stem Cells: Implications for Cell Autonomous Studies
Tyler Joseph Dause, Elizabeth Diana Kirby
eNeuro 20 February 2020, 7 (2) ENEURO.0470-19.2020; DOI: 10.1523/ENEURO.0470-19.2020

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Poor Concordance of Floxed Sequence Recombination in Single Neural Stem Cells: Implications for Cell Autonomous Studies
Tyler Joseph Dause, Elizabeth Diana Kirby
eNeuro 20 February 2020, 7 (2) ENEURO.0470-19.2020; DOI: 10.1523/ENEURO.0470-19.2020
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Keywords

  • adult neurogenesis
  • cell autonomous
  • CreERT2 recombinase
  • hippocampus
  • neural stem cells
  • subventricular zone

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