Research ArticleResearch Article: New Research, Disorders of the Nervous System

EGFR Signaling Causes Morphine Tolerance and Mechanical Sensitization in Rats

Stephanie Puig, Courtney L. Donica and Howard B. Gutstein
eNeuro 28 February 2020, 7 (2) ENEURO.0460-18.2020; https://doi.org/10.1523/ENEURO.0460-18.2020

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0460-18.2020
PubMed 
32111605
Published By 
Society for Neuroscience
History 
  • Received November 22, 2018
  • Revision received December 29, 2018
  • Accepted February 17, 2020
  • Published online February 28, 2020.
Copyright & Usage 
Copyright © 2020 Puig et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Stephanie Puig1,
  2. Courtney L. Donica2 and
  3. Howard B. Gutstein3
  1. 1Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213
  2. 2 University of Houston, Houston, TX 77030
  3. 3 Anesthesiology Institute, Allegheny Health Network, Pittsburgh, PA 15224
  1. Correspondence should be addressed to Howard B. Gutstein at gutsteinh{at}gmail.com.
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Author contributions

  1. Author contributions: S.P., C.L.D., and H.B.G. designed research; S.P. and C.L.D. performed research; S.P., C.L.D., and H.B.G. analyzed data; S.P. and H.B.G. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the National Institutes of Health Grant DA038660 (to H.B.G.).

Funding

  • HHS | NIH | National Institute on Drug Abuse (NIDA)

    R01DA038660

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Article usage: February 2020 to January 2025

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Total81537981048
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eneuro: 7 (2)
eNeuro
Vol. 7, Issue 2
March/April 2020
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EGFR Signaling Causes Morphine Tolerance and Mechanical Sensitization in Rats
Stephanie Puig, Courtney L. Donica, Howard B. Gutstein
eNeuro 28 February 2020, 7 (2) ENEURO.0460-18.2020; DOI: 10.1523/ENEURO.0460-18.2020
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