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Research ArticleResearch Article: New Research, Novel Tools and Methods

Localized Calcium Signaling and the Control of Coupling at Cx36 Gap Junctions

Keith B. Moore, Cheryl K. Mitchell, Ya-Ping Lin, Yuan-Hao Lee, Eyad Shihabeddin and John O’Brien
eNeuro 16 March 2020, 7 (2) ENEURO.0445-19.2020; DOI: https://doi.org/10.1523/ENEURO.0445-19.2020
Keith B. Moore
1Richard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030
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Cheryl K. Mitchell
1Richard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030
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Ya-Ping Lin
1Richard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030
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Yuan-Hao Lee
1Richard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030
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Eyad Shihabeddin
1Richard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030
2The MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030
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John O’Brien
1Richard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030
2The MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0445-19.2020
PubMed 
32179580
Published By 
Society for Neuroscience
History 
  • Received October 25, 2019
  • Revision received January 29, 2020
  • Accepted February 21, 2020
  • Published online March 16, 2020.
Copyright & Usage 
Copyright © 2020 Moore et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Keith B. Moore1,
  2. Cheryl K. Mitchell1,
  3. Ya-Ping Lin1,
  4. Yuan-Hao Lee1,
  5. Eyad Shihabeddin1,2 and
  6. John O’Brien1,2
  1. 1Richard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030
  2. 2The MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030
  1. Correspondence should be addressed to John O’Brien at john.obrien{at}uth.tmc.edu.
  • K. B. Moore’s present address: School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030.

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Author contributions

  1. Author contributions: K.B.M. and J.O. designed research; K.B.M., C.K.M., Y.-P.L., Y.-H.L., and J.O. performed research; K.B.M., C.K.M., E.S., and J.O. analyzed data; K.B.M. and J.O. wrote the paper.

  • K. B. Moore’s present address: School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030.

Disclosures

  • The authors declare no competing financial interests.

  • This research was supported by the National Institutes of Health Grant R01 EY012857 (J.O.), Core Grant P30 EY028102, and the Louisa Stude Sarofim endowment (J.O.). K.B.M. was supported by Training Grant T32 EY007024.

Funding

  • HHS | NIH | National Eye Institute (NEI)

    R01 EY012857; T32 EY007024; P30 EY028102
  • Louisa Stude Sarofim Endowment

Other Version

  • You are viewing the most recent version of this article.
  • previous version (March 16, 2020).

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Mar 20203300102
May 20207451457
Jun 20203382227
Jul 20201752423
Aug 20202391524
Sep 20202181831
Oct 20201385411
Nov 20201188018
Dec 20209132513
Total 20205316652306
Jan 2021889619
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Apr 20211685826
May 20211387714
Jun 202114105211
Jul 2021966010
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Sep 2021738335
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Total 20211057445258
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Feb 2022110614
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Apr 202215923
May 202219222
Jun 2022110424
Jul 202249218
Aug 202227112
Sep 202239134
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Total 2022281048223
Jan 202359614
Total 202359614
Total66915241801
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Localized Calcium Signaling and the Control of Coupling at Cx36 Gap Junctions
Keith B. Moore, Cheryl K. Mitchell, Ya-Ping Lin, Yuan-Hao Lee, Eyad Shihabeddin, John O’Brien
eNeuro 16 March 2020, 7 (2) ENEURO.0445-19.2020; DOI: 10.1523/ENEURO.0445-19.2020

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Localized Calcium Signaling and the Control of Coupling at Cx36 Gap Junctions
Keith B. Moore, Cheryl K. Mitchell, Ya-Ping Lin, Yuan-Hao Lee, Eyad Shihabeddin, John O’Brien
eNeuro 16 March 2020, 7 (2) ENEURO.0445-19.2020; DOI: 10.1523/ENEURO.0445-19.2020
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Keywords

  • calcium signaling
  • Connexin 36
  • electrical synapse
  • optical imaging
  • Plasticity
  • tracer coupling

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