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Research ArticleResearch Article: New Research, Neuronal Excitability

Chronic Activation of Gp1 mGluRs Leads to Distinct Refinement of Neural Network Activity through Non-Canonical p53 and Akt Signaling

Dai-Chi Liu, Stephanie Soriano, Yeeun Yook, Simon Lizarazo, Daphne E. Eagleman and Nien-Pei Tsai
eNeuro 11 March 2020, 7 (2) ENEURO.0438-19.2020; https://doi.org/10.1523/ENEURO.0438-19.2020
Dai-Chi Liu
1Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL 61801
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Stephanie Soriano
1Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL 61801
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Yeeun Yook
2Department of Molecular and Integrative Physiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801
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Simon Lizarazo
2Department of Molecular and Integrative Physiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801
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Daphne E. Eagleman
2Department of Molecular and Integrative Physiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801
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Nien-Pei Tsai
1Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL 61801
2Department of Molecular and Integrative Physiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0438-19.2020
PubMed 
32161037
Published By 
Society for Neuroscience
History 
  • Received October 23, 2019
  • Revision received January 17, 2020
  • Accepted March 2, 2020
  • Published online March 11, 2020.
Copyright & Usage 
Copyright © 2020 Liu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Dai-Chi Liu1,
  2. Stephanie Soriano1,
  3. Yeeun Yook2,
  4. Simon Lizarazo2,
  5. Daphne E. Eagleman2 and
  6. Nien-Pei Tsai1,2
  1. 1Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL 61801
  2. 2Department of Molecular and Integrative Physiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801
  1. Correspondence should be addressed to Nien-Pei Tsai at nptsai{at}illinois.edu.
View Full Text

Author contributions

  1. Author contributions: D.-C.L. and N.-P.T. designed research; D.-C.L., S.S., Y.Y., S.L., D.E.E., and N.-P.T. performed research; D.-C.L., S.S., Y.Y., S.L., D.E.E., and N.-P.T. analyzed data; N.-P.T. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work is supported by the startup fund provided by the School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, by National Institute of Health Grant R01NS105615 (to N-P.T.), by the Brain and Behavioral Research Foundation National Alliance for Research on Schizophrenia and Depression Young Investigator Grant 27018 (to N-P.T.), and by the Campus Research Board of University of Illinois at Urbana-Champaign Grant RB20004 (to N-P.T.).

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    R01NS105615
  • Brain and Behavior Research Foundation (Brain & Behavior Research Foundation)

    27018
  • UofI | University of Illinois at Urbana-Champaign (UIUC)

    RB20004

Other Version

  • You are viewing the most recent version of this article.
  • previous version (March 11, 2020).

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AbstractFullPdf
Mar 2020464140176
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Jun 20202818116
Jul 202095423
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Apr 2021107917
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Jun 202586016
Jul 202586024
Aug 202584817
Sep 20251111815
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Total 202582741196
Total83739311174
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Chronic Activation of Gp1 mGluRs Leads to Distinct Refinement of Neural Network Activity through Non-Canonical p53 and Akt Signaling
Dai-Chi Liu, Stephanie Soriano, Yeeun Yook, Simon Lizarazo, Daphne E. Eagleman, Nien-Pei Tsai
eNeuro 11 March 2020, 7 (2) ENEURO.0438-19.2020; DOI: 10.1523/ENEURO.0438-19.2020

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Chronic Activation of Gp1 mGluRs Leads to Distinct Refinement of Neural Network Activity through Non-Canonical p53 and Akt Signaling
Dai-Chi Liu, Stephanie Soriano, Yeeun Yook, Simon Lizarazo, Daphne E. Eagleman, Nien-Pei Tsai
eNeuro 11 March 2020, 7 (2) ENEURO.0438-19.2020; DOI: 10.1523/ENEURO.0438-19.2020
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