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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Reduced TUBA1A Tubulin Causes Defects in Trafficking and Impaired Adult Motor Behavior

Georgia Buscaglia, Kyle R. Northington, Jeffrey K. Moore and Emily Anne Bates
eNeuro 17 March 2020, 7 (2) ENEURO.0045-20.2020; DOI: https://doi.org/10.1523/ENEURO.0045-20.2020
Georgia Buscaglia
1Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora CO 80045
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Kyle R. Northington
1Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora CO 80045
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Jeffrey K. Moore
2Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045
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Emily Anne Bates
1Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora CO 80045
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0045-20.2020
PubMed 
32184299
Published By 
Society for Neuroscience
History 
  • Received February 10, 2020
  • Accepted March 3, 2020
  • Published online March 17, 2020.
Copyright & Usage 
Copyright © 2020 Buscaglia et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Georgia Buscaglia1,
  2. Kyle R. Northington1,
  3. Jeffrey K. Moore2 and
  4. Emily Anne Bates1
  1. 1Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora CO 80045
  2. 2Department of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045
  1. Correspondence should be addressed to Emily Anne Bates at emily.bates{at}cuanschutz.edu.
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Author contributions

  1. Author contributions: G.B., J.K.M., and E.A.B. designed research; G.B., K.R.N., performed research; G.B., K.R.N., analyzed data; J.K.M., and E.A.B. edited the final manuscript; G.B. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the University of Colorado Movement Disorder Center (E.A.B.), the Department of Cell and Developmental Biology (J.K.M.), and the National Institutes of Health Grant 5R01GM112893-05 (to J.K.M.).

Funding

  • University of Colorado Movement Disorder Center

    N/A
  • HHS | National Institutes of Health (NIH)

    5RO1GM112893-05; T32 NS 099042
  • Department of Cell and Developmental Biology, University of Colorado

Other Version

  • You are viewing the most recent version of this article.
  • previous version (March 17, 2020).

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Mar 20203410133
May 20207313545
Jun 2020335020
Jul 202082817
Aug 2020214330
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Oct 2020108213
Nov 202055713
Dec 202026615
Total 2020515496303
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Feb 202305211
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Jun 202305732
Jul 202305326
Aug 202365026
Sep 202355012
Total 202317494187
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eneuro: 7 (2)
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March/April 2020
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Reduced TUBA1A Tubulin Causes Defects in Trafficking and Impaired Adult Motor Behavior
Georgia Buscaglia, Kyle R. Northington, Jeffrey K. Moore, Emily Anne Bates
eNeuro 17 March 2020, 7 (2) ENEURO.0045-20.2020; DOI: 10.1523/ENEURO.0045-20.2020

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Reduced TUBA1A Tubulin Causes Defects in Trafficking and Impaired Adult Motor Behavior
Georgia Buscaglia, Kyle R. Northington, Jeffrey K. Moore, Emily Anne Bates
eNeuro 17 March 2020, 7 (2) ENEURO.0045-20.2020; DOI: 10.1523/ENEURO.0045-20.2020
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Keywords

  • ataxia
  • microtubule network
  • movement disorder
  • trafficking
  • TUBA1A
  • tubulin

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