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Research ArticleNew Research, Cognition and Behavior

Optogenetic Activation of β-Endorphin Terminals in the Medial Preoptic Nucleus Regulates Female Sexual Receptivity

Caroline Johnson, Weizhe Hong and Paul Micevych
eNeuro 15 January 2020, 7 (1) ENEURO.0315-19.2019; https://doi.org/10.1523/ENEURO.0315-19.2019
Caroline Johnson
1Department of Neurobiology David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095
2Laboratory of Neuroendocrinology of the Brain Research Institute, University of California, Los Angeles, Los Angeles, CA 90095
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Weizhe Hong
1Department of Neurobiology David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095
2Laboratory of Neuroendocrinology of the Brain Research Institute, University of California, Los Angeles, Los Angeles, CA 90095
3Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095
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Paul Micevych
1Department of Neurobiology David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095
2Laboratory of Neuroendocrinology of the Brain Research Institute, University of California, Los Angeles, Los Angeles, CA 90095
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0315-19.2019
PubMed 
31941660
Published By 
Society for Neuroscience
History 
  • Received August 6, 2019
  • Revision received November 15, 2019
  • Accepted November 19, 2019
  • Published online January 15, 2020.
Copyright & Usage 
Copyright © 2020 Johnson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Caroline Johnson1,2,
  2. Weizhe Hong1,2,3 and
  3. Paul Micevych1,2
  1. 1Department of Neurobiology David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095
  2. 2Laboratory of Neuroendocrinology of the Brain Research Institute, University of California, Los Angeles, Los Angeles, CA 90095
  3. 3Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095
  1. Correspondence should be addressed to Caroline Johnson at csjohnson{at}mednet.ucla.edu.
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Author contributions

  1. Author contributions: C.J. performed research; C.J. analyzed data; C.S.J. and P.M. wrote the paper; W.H., C.J., and P.M. designed research.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the National Institutes of Health Grant DA013185 (to P.M.).

Funding

  • HHS | NIH | National Institute on Drug Abuse (NIDA)

    DA013185

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  • You are viewing the most recent version of this article.
  • previous version (January 15, 2020).

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Optogenetic Activation of β-Endorphin Terminals in the Medial Preoptic Nucleus Regulates Female Sexual Receptivity
Caroline Johnson, Weizhe Hong, Paul Micevych
eNeuro 15 January 2020, 7 (1) ENEURO.0315-19.2019; DOI: 10.1523/ENEURO.0315-19.2019

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Optogenetic Activation of β-Endorphin Terminals in the Medial Preoptic Nucleus Regulates Female Sexual Receptivity
Caroline Johnson, Weizhe Hong, Paul Micevych
eNeuro 15 January 2020, 7 (1) ENEURO.0315-19.2019; DOI: 10.1523/ENEURO.0315-19.2019
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Keywords

  • β-endorphin
  • estradiol
  • lordosis
  • μ-opioid receptor
  • POMC

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