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PreviousNext
Research ArticleNew Research, Neuronal Excitability

TrkB Signaling Influences Gene Expression in Cortistatin-Expressing Interneurons

Kristen R. Maynard, Alisha Kardian, Julia L. Hill, Yishan Mai, Brianna Barry, Henry L. Hallock, Andrew E. Jaffe and Keri Martinowich
eNeuro 15 January 2020, 7 (1) ENEURO.0310-19.2019; https://doi.org/10.1523/ENEURO.0310-19.2019
Kristen R. Maynard
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205
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  • ORCID record for Kristen R. Maynard
Alisha Kardian
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205
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Julia L. Hill
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205
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Yishan Mai
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205
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Brianna Barry
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205
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Henry L. Hallock
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205
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Andrew E. Jaffe
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205
2Department of Mental Health, Johns Hopkins University, Baltimore, Maryland 21205
3Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205
4Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287
5The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
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Keri Martinowich
1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205
4Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287
5The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0310-19.2019
PubMed 
31941661
Published By 
Society for Neuroscience
History 
  • Received August 1, 2019
  • Revision received November 14, 2019
  • Accepted December 4, 2019
  • Published online January 15, 2020.
Copyright & Usage 
Copyright © 2020 Maynard et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Kristen R. Maynard1,*,
  2. Alisha Kardian1,*,
  3. Julia L. Hill1,
  4. Yishan Mai1,
  5. Brianna Barry1,
  6. Henry L. Hallock1,
  7. Andrew E. Jaffe1,2,3,4,5 and
  8. Keri Martinowich1,4,5
  1. 1Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland 21205
  2. 2Department of Mental Health, Johns Hopkins University, Baltimore, Maryland 21205
  3. 3Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205
  4. 4Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287
  5. 5The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
  1. Correspondence should be addressed to Keri Martinowich at Keri.martinowich{at}libd.org.
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Author contributions

  1. Author contributions: K.R.M., J.L.H., and K.M. designed research; K.R.M., A.K., J.L.H., Y.M., B.B., and H.L.H. performed research; K.R.M., A.K., B.B., and A.E.J. analyzed data; K.R.M., A.K., A.E.J., and K.M. wrote the paper.

  2. ↵* K.R.M. and A.K. contributed equally to this work.

Disclosures

  • The authors declare no competing financial interest.

  • Funding for these studies was provided by the Lieber Institute for Brain Development, the National Institute of Mental Health (Grant R01-MH-105592 to K.M.), and the National Institute of General Medical Sciences (Grant T32-GM-007445 to B.B.).

Funding

  • Lieber Institute for Brain Development

  • HHS | NIH | National Institute of Mental Health (NIMH)

    RO1MH105592
  • HHS | NIH | National Institute of General Medical Sciences (NIGMS)

    T32GM007445

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  • You are viewing the most recent version of this article.
  • previous version (January 15, 2020).

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Total121157261732
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TrkB Signaling Influences Gene Expression in Cortistatin-Expressing Interneurons
Kristen R. Maynard, Alisha Kardian, Julia L. Hill, Yishan Mai, Brianna Barry, Henry L. Hallock, Andrew E. Jaffe, Keri Martinowich
eNeuro 15 January 2020, 7 (1) ENEURO.0310-19.2019; DOI: 10.1523/ENEURO.0310-19.2019

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TrkB Signaling Influences Gene Expression in Cortistatin-Expressing Interneurons
Kristen R. Maynard, Alisha Kardian, Julia L. Hill, Yishan Mai, Brianna Barry, Henry L. Hallock, Andrew E. Jaffe, Keri Martinowich
eNeuro 15 January 2020, 7 (1) ENEURO.0310-19.2019; DOI: 10.1523/ENEURO.0310-19.2019
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Keywords

  • ASD
  • BDNF-TrkB
  • cortistatin
  • epilepsy
  • inhibitory interneurons
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