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Research ArticleNew Research, Novel Tools and Methods

Optogenetic Control of Spine-Head JNK Reveals a Role in Dendritic Spine Regression

Patrik Hollos, Jismi M. John, Jukka V. Lehtonen and Eleanor T. Coffey
eNeuro 14 January 2020, 7 (1) ENEURO.0303-19.2019; https://doi.org/10.1523/ENEURO.0303-19.2019
Patrik Hollos
1Turku Bioscience, University of Turku and Åbo Akademi University, Turku FI-20500, Finland
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Jismi M. John
1Turku Bioscience, University of Turku and Åbo Akademi University, Turku FI-20500, Finland
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Jukka V. Lehtonen
2Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, Åbo FI-20500, Finland
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  • ORCID record for Jukka V. Lehtonen
Eleanor T. Coffey
1Turku Bioscience, University of Turku and Åbo Akademi University, Turku FI-20500, Finland
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0303-19.2019
PubMed 
31937523
Published By 
Society for Neuroscience
History 
  • Received July 30, 2019
  • Revision received December 18, 2019
  • Accepted December 19, 2019
  • Published online January 14, 2020.
Copyright & Usage 
Copyright © 2020 Hollos et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Patrik Hollos1,
  2. Jismi M. John1,
  3. Jukka V. Lehtonen2 and
  4. Eleanor T. Coffey1
  1. 1Turku Bioscience, University of Turku and Åbo Akademi University, Turku FI-20500, Finland
  2. 2Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, Åbo FI-20500, Finland
  1. Correspondence should be addressed to Eleanor T. Coffey at eleanor.coffey{at}bioscience.fi.
View Full Text

Author contributions

  1. Author contributions: P.H., J.V.L., and E.T.C. designed research; P.H. and J.M.J. performed research; P.H. and J.M.J. analyzed data; P.H. and E.T.C. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the Academy of Finland Grants 135090 and 310583 EU FP7 ITN 608346 rBIRTH (to E.T.C.) and by the Molecular Biology Graduate School at Åbo Akademi University (P.H.).

Funding

  • Academy of Finland | Biotieteiden ja Ympäristön Tutkimuksen Toimikunta (Forskningsrådet för Biovetenskap och Miljö)

    135090
  • EU FP7 ITN r'BIRTH

    #608346
  • Åbo Akademi Molecular Biology Graduate School

  • Academy of Finland | Terveyden Tutkimuksen Toimikunta (Forskningsrådet för Hälsa)

    28200214

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  • You are viewing the most recent version of this article.
  • previous version (January 14, 2020).

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Optogenetic Control of Spine-Head JNK Reveals a Role in Dendritic Spine Regression
Patrik Hollos, Jismi M. John, Jukka V. Lehtonen, Eleanor T. Coffey
eNeuro 14 January 2020, 7 (1) ENEURO.0303-19.2019; DOI: 10.1523/ENEURO.0303-19.2019

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Optogenetic Control of Spine-Head JNK Reveals a Role in Dendritic Spine Regression
Patrik Hollos, Jismi M. John, Jukka V. Lehtonen, Eleanor T. Coffey
eNeuro 14 January 2020, 7 (1) ENEURO.0303-19.2019; DOI: 10.1523/ENEURO.0303-19.2019
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Keywords

  • elimination
  • hippocampal neurons
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