a | Normal | Raldh2 mRNA puncta/mm; unpaired t test between genotypes at P2, one-tailed | –2521 to –1732 |
b | Normal | PDGFRβ+ structures/mm2; unpaired t test between genotypes at P14, two-tailed | –42.62 to 16.82 |
c | Normal | Laminin+ structures/mm2; unpaired t test between genotypes at P14, two-tailed | –94.79 to 21.25 |
d | Normal | PDGFRβ+Laminin+/Laminin+ structures %, unpaired t test between genotypes at P14, two-tailed | –2.765 to 21.69 |
e | Normal | OLIG2+ cells/mm2; one-way ANOVA with Sidak’s test between genotypes at individual time points | |
| | P2 | 4.080 to 494.0 |
| | P7 | 80.47 to 547.6 |
| | P14 | 126.6 to 593.7 |
| | P21 | 108.9 to 681.0 |
f | Normal | OLIG2+ cells/mm2; unpaired t test within control genotype between individual time points P2 vs P21, one-tailed | –441.0 to 282.2 |
g | Normal | OLIG2+ cells/mm2; unpaired t test within cKO genotype between individual time points P2 vs P21, one-tailed | –490.0 to 39.44 |
h | Normal | PDGFRα+OLIG2+ cells/mm2; one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points | |
i | Normal | PDGFRα+OLIG2+ cells/mm2; one-way ANOVA with Sidak’s test for multiple comparisons within control genotype at individual time points | |
| | P2 vs P7 | –121.2 to 55.21 |
| | P7 vs P14 | –184.2 to –16.61 |
| | P14 vs P21 | 8.089 to 221.1 |
| | P2 vs P21 | –224.6 to –42.19 |
j | Normal | PDGFRα+OLIG2+/OLIG2+ cells/mm2; one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points | |
| | P2 | –26.25 to –9.080 |
| | P7 | –21.13 to –3.288 |
| | P14 | –20.19 to –1.376 |
| | P21 | –12.09 to 6.720 |
k | Normal | CC1+OLIG2+ cells/mm2; one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points | |
| | P7 | –21.38 to 87.30 |
| | P14 | 32.72 to 141.4 |
| | P21 | 49.38 to 158.1 |
l | Normal | CC1+OLIG2+ cells/OLIG2+ cells %; one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points | |
| | P14 | 2.156 to 20.30 |
| | P21 | 1.024 to 19.16 |
m | Normal | PLP+ area (mm2); one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points | |
| | P7 | –18.20 to 107.8 |
| | P14 | 30.06 to 138.5 |
| | P21 | 25.44 to 139.2 |
| | P120 | 69.15 to 211.4 |
n | Normal | TUNEL+ cells/mm2; unpaired t test within control genotype between individual time points P2 vs P7, one-tailed | –41.86 to –15.94 |
o | Normal | TUNEL+ cells/mm2; unpaired t test within cKO genotype between individual time points P2 vs P7, one-tailed | –18.13 to 4.871 |
p | Normal | TUNEL+ cells/mm2; one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points | |
| | P2 | –9.109 to 16.03 |
| | P7 | –30.05 to –7.565 |
| | P14 | 0.9951 to 10.17 |
q | Normal | IBA1+ cells/mm2 one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points | |
| | P7 | –46.17 to 51.34 |
| | P14 | –92.57 to 4.941 |
| | P21 | –37.76 to 67.56 |
r | Normal | Gli1 mRNA puncta/mm2; unpaired t test between genotypes at P2, one-tailed | –15,405 to –2876 |
s | Normal | Gli1 mRNA puncta/cell; n= number of cells, unpaired t test between genotypes at P2, one-tailed | –3.692 to –1.703 |
t | Normal | Gli1+Olig2+ cells/mm2; unpaired t test between genotypes at P2, one-tailed | –53.01 to –33.57 |
u | Normal | ÄGFAP+ area (mm2); one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points | |
| | P2 | 0.8137 to 7.880 |
| | P7 | 4.695 to 12.44 |
| | P14 | 6.558 to 14.30 |
| | P21 | 3.638 to 11.38 |
v | Normal | SATB2+ cells/mm2; unpaired t test between genotypes at P2, one-tailed | 159.9 to 1991 |
w | Normal | CTIP2+ cells/mm2; unpaired t test between genotypes at P2, two-tailed | –172.6 to –68.02 |
x | Normal | TBR1+ cells/mm2; unpaired t test between genotypes at P2, two-tailed | –1407 to –439.5 |
y | Normal | Cortical thickness (um); unpaired t test between genotypes at P2, two-tailed | –234.6 to 26.12 |