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Research ArticleNew Research, Development

“Females Are Not Just ‘Protected’ Males”: Sex-Specific Vulnerabilities in Placenta and Brain after Prenatal Immune Disruption

Amy E. Braun, Pamela A. Carpentier, Brooke A. Babineau, Aditi R. Narayan, Michelle L. Kielhold, Hyang Mi Moon, Archana Shankar, Jennifer Su, Vidya Saravanapandian, Ursula Haditsch and Theo D. Palmer
eNeuro 14 October 2019, 6 (6) ENEURO.0358-19.2019; DOI: https://doi.org/10.1523/ENEURO.0358-19.2019
Amy E. Braun
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
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Pamela A. Carpentier
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
2Driskill Graduate Program in Life Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611
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Brooke A. Babineau
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
3Unity Biotechnology, Brisbane, California 94005
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Aditi R. Narayan
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
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Michelle L. Kielhold
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
4Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, Oregon 97239
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Hyang Mi Moon
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
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Archana Shankar
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
5Department of Biological Science, California State University, Fullerton, Fullerton, California 92831
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Jennifer Su
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
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Vidya Saravanapandian
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
6Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California 92093
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Ursula Haditsch
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
7Cortexyme, Inc, South San Francisco, California 94080
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Theo D. Palmer
1Institute for Stem Cell Biology and Regenerative Medicine and Department of Neurosurgery, Stanford University, Stanford, California 94305-5454
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“Females Are Not Just ‘Protected’ Males”: Sex-Specific Vulnerabilities in Placenta and Brain after Prenatal Immune Disruption
Amy E. Braun, Pamela A. Carpentier, Brooke A. Babineau, Aditi R. Narayan, Michelle L. Kielhold, Hyang Mi Moon, Archana Shankar, Jennifer Su, Vidya Saravanapandian, Ursula Haditsch, Theo D. Palmer
eNeuro 14 October 2019, 6 (6) ENEURO.0358-19.2019; DOI: 10.1523/ENEURO.0358-19.2019

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“Females Are Not Just ‘Protected’ Males”: Sex-Specific Vulnerabilities in Placenta and Brain after Prenatal Immune Disruption
Amy E. Braun, Pamela A. Carpentier, Brooke A. Babineau, Aditi R. Narayan, Michelle L. Kielhold, Hyang Mi Moon, Archana Shankar, Jennifer Su, Vidya Saravanapandian, Ursula Haditsch, Theo D. Palmer
eNeuro 14 October 2019, 6 (6) ENEURO.0358-19.2019; DOI: 10.1523/ENEURO.0358-19.2019
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Keywords

  • corticogenesis
  • developmental origins of health and disease
  • female resilience
  • maternal immune activation
  • pregnancy complications
  • sex differences

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