Silhouette-Length-Scaled Gait Parameters for Motor Functional Analysis in Mice and Rats

Ivanna K. Timotius; Sandra Moceri; Anne-Christine Plank; Johanna Habermeyer; Fabio Canneva; Jürgen Winkler; Jochen Klucken; Nicolas Casadei; Olaf Riess; Bjoern Eskofier; Stephan von Hörsten

doi:10.1523/ENEURO.0100-19.2019

Article Information

DOI

https://doi.org/10.1523/ENEURO.0100-19.2019

PubMed

31604813

Published By

Society for Neuroscience

History

Received March 15, 2019
Revision received July 29, 2019
Accepted August 1, 2019
Published online October 11, 2019.

Copyright © 2019 Timotius et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

Ivanna K. Timotius¹,⁴,
Sandra Moceri²,
Anne-Christine Plank²,
Johanna Habermeyer²,
Fabio Canneva²,
Jürgen Winkler³,
Jochen Klucken³,
Nicolas Casadei⁵,
Olaf Riess⁵,
Bjoern Eskofier¹ and
Stephan von Hörsten²

¹Machine Learning and Data Analytics Lab, Department of Computer Science, Faculty of Engineering, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91052 Erlangen-Nürnberg, Germany
²Department Experimental Therapy, University Hospital Erlangen (UKEr) and Preclinical Experimental Animal Center, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen-Nürnberg, Germany
³Department of Molecular Neurology, University Hospital Erlangen (UKEr), Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen-Nürnberg, Germany
⁴Department of Electronics Engineering, Satya Wacana Christian University, Salatiga 50711, Indonesia
⁵Institute of Medical Genetics and Applied Genomics, University of Tübingen, 72076 Tübingen, Germany

Correspondence should be addressed to Stephan von Hörsten at Stephan.v.hoersten{at}fau.de.

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Author contributions

Author contributions: I.K.T., S.M., A.-C.P., J.H., F.C., and S.v.H. performed research; I.K.T., S.M., A.-C.P., F.C., and S.v.H. analyzed data; I.K.T., S.M., A.-C.P., B.E., and S.v.H. wrote the paper; J.H., J.W., J.K., N.C., O.R., and B.E. contributed unpublished reagents/analytic tools; I.K.T., F.C., J.K., B.E., and S.v.H. designed research.

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Disclosures

The authors declare no competing financial interests.
I.K.T. received financial support from DAAD for research studies (Research Grant 57129429). S.M., A.-C.P., J.H., F.C. and S.v.H., were supported by the EU Joint Programme-Neurodegenerative Disease Research (JPND) project CrossSeeds (Grant 01ED1501C). J.W. and J.K. were supported by the Interdisciplinary Center of Clinical Research (IZKF; Grants E21 and E11) of the University Hospital Erlangen, Germany, and the Bavarian State Ministry of Education and Culture, Science and Arts in the framework of the Bavarian Research Network for Induced Pluripotent Stem Cells (ForIPS) and the European Institute of Innovation and Technology Health (EIT Health; MoveIT). J.K. was supported by the Deutsche Forschungsgemeinschaft (DFG; Grant KL1395/8-1). N.C. and O.R. were supported by NEURASYNC: an Academic Industrial Initial Training Network (ITN) through the people program FP7 of the European Union and FCT (Grant PTDC/SAU-NEU/105215/2008). B.E. was supported by the DFG within the framework of the Heisenberg Professorship program (Grant ES 434/8-1). S.M., F.C., and S.v.H. acknowledge the support by the JPND project CrossSeeds (Grant 01ED1501C). This research was supported by the DFG and Friedrich-Alexander-Universität Erlangen-Nürnberg within the funding program Open Access Publishing.