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Research ArticleNew Research, Sensory and Motor Systems

Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation

Erica Tracey Akhter, Ronald W. Griffith, Arthur W. English and Francisco J. Alvarez
eNeuro 20 September 2019, 6 (5) ENEURO.0172-19.2019; https://doi.org/10.1523/ENEURO.0172-19.2019
Erica Tracey Akhter
1Departments of Physiology, Emory University, Atlanta, GA 30322
2Cell Biology, Emory University, Atlanta, GA 30322
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  • ORCID record for Erica Tracey Akhter
Ronald W. Griffith
1Departments of Physiology, Emory University, Atlanta, GA 30322
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Arthur W. English
2Cell Biology, Emory University, Atlanta, GA 30322
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Francisco J. Alvarez
1Departments of Physiology, Emory University, Atlanta, GA 30322
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0172-19.2019
PubMed 
31541001
Published By 
Society for Neuroscience
History 
  • Received May 9, 2019
  • Revision received August 21, 2019
  • Accepted September 15, 2019
  • Published online September 20, 2019.
Copyright & Usage 
Copyright © 2019 Akhter et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Erica Tracey Akhter1,2,
  2. Ronald W. Griffith1,
  3. Arthur W. English2 and
  4. Francisco J. Alvarez1
  1. 1Departments of Physiology, Emory University, Atlanta, GA 30322
  2. 2Cell Biology, Emory University, Atlanta, GA 30322
  1. Correspondence should be addressed to Francisco J. Alvarez at francisco.j.alvarez{at}emory.edu.
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Author contributions

  1. Author contributions: E.T.A., A.W.E., and F.J.A. designed research; E.T.A., R.W.G., and F.J.A. performed research; E.T.A. and F.J.A. analyzed data; E.T.A., A.W.E., and F.J.A. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by National Institutes of Health, National Institute of Neurological Disorders and Stroke Grants P01NS057228 and R56NS099092 (to F.J.A.) and NS057190 and 032571 (to A.W.E.) and by the National Science Foundation Graduate Fellowship DGE-1444932 (to E.T.A.).

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    P01NS057228; R56NS099092; NS057190; NS032571
  • NSF | Directorate for Biological Sciences (BIO)

    DGE-1444932

Other Version

  • You are viewing the most recent version of this article.
  • previous version (September 20, 2019).

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September/October 2019
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Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation
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Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation
Erica Tracey Akhter, Ronald W. Griffith, Arthur W. English, Francisco J. Alvarez
eNeuro 20 September 2019, 6 (5) ENEURO.0172-19.2019; DOI: 10.1523/ENEURO.0172-19.2019

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Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation
Erica Tracey Akhter, Ronald W. Griffith, Arthur W. English, Francisco J. Alvarez
eNeuro 20 September 2019, 6 (5) ENEURO.0172-19.2019; DOI: 10.1523/ENEURO.0172-19.2019
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Keywords

  • excitability
  • GABA
  • KCC2
  • nerve injury
  • neuromuscular junction
  • regeneration

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