*a* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | 0.1319194 | Fos 1 h, blue, 10 Hz |
Figure 1 |

*b* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | 0.6031834 | Fos 6 h, blue, 10 Hz |
Figure 1 |

*c* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | −0.249898 | Fos 1 h, red, 10 Hz |
Figure 1 |

*d* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | −0.02737114 | Fos 6 h, red, 10 Hz |
Figure 1 |

*e* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | −0.8537 | Fos 1 h, green, 10 Hz |
Figure 1 |

*f* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | −0.3404513 | Fos 6 h, green, 10 Hz |
Figure 1 |

*g* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | 1.83808 | Fos, 6 h, blue, 100 Hz |
Figure 2 |

*h* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | 0.3375841 | Fos, 6 h, blue, low power, 100 Hz |
Figure 2 |

*i* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | −0.456429 | Fos, 6 h, red, 100 Hz |
Figure 2 |

*j* | Normal | Two-sided Student’s *t* test on log fold changes | 0.521899 1.763154 | Fos 100 Hz vs 10 Hz, blue |
Figures 1, 2 |

*k* | Normal | Two-sided Student’s *t* test on log fold changes | −1.774112 2.339614 | Fos 100 Hz high power vs Fos 100 Hz low power |
Figure 2 |

*l* | Normal | Two-sided Student’s *t* test | −1.5504421 −0.1162245 | Temperature: 10 Hz blue vs 100 Hz blue at 5 min |
Figure 3 |

*m* | Normal | Two-sided Student’s *t* test | −3.926551 2.426551 | Temperature: 100 Hz blue vs 100 Hz red at 5 min |
Figure 3 |

*n* | Normal | Two-sided Student’s *t* test | −1.38377545 0.05044212 | Temperature: 10 Hz blue vs 100 Hz blue at 15 min |
Figure 3 |

*o* | Normal | Two-sided Student’s *t* test | −1.7777220 0.9443886 | Temperature: 100 Hz blue vs 100 Hz red at 15 min |
Figure 3 |

*p* | Normal | Two-sided Student’s *t* test | −1.5504421 −0.1162245 | Temperature: 10 Hz blue vs 100 Hz blue at 6 h |
Figure 3 |

*q* | Normal | Two-sided Student’s *t* test | −3.426551 2.926551 | Temperature: 100 Hz blue vs 100 Hz red at 6 h |
Figure 3 |

*r* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | 0.144 | Bdnf, 6 h, blue, 10 Hz |
Figure 4 |

*s* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | −0.061 | Bdnf, 6 h, red, 10 Hz |
Figure 4 |

*t* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | −0.52 | Bdnf, 6 h, green, 10 Hz |
Figure 4 |

*u* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | 0.2876212 | Npas4, 6 h, blue, 10 Hz |
Figure 4 |

*v* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | −0.05463496 | Npas4, 6 h, red, 10 Hz |
Figure 4 |

*w* | Normal | One-sided Student’s *t* test on log fold change, test difference from log(1) | −0.6481334 | Npas4, 6 h, green, 10 Hz |
Figure 4 |

*x* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −0.23030841 0.02717987 | Thy1, 6 h, blue, 100 Hz, 3.9 mW/mm^{2} |
Figure 4 |

*y* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −0.4856258 1.1311706 | Thy1, 6 h, blue, 100 Hz, 2.95 mW/mm^{2} |
Figure 4 |

*z* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −0.1336059 0.3427545 | Thy1, 6 h, red, 100 Hz |
Figure 4 |

*aa* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.9422738 0.3562803 | Tubb3, 6 h, blue, 100 Hz, 3.9 mW/mm^{2} |
Figure 4 |

*bb* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.14604760 0.08778751 | Tubb3, 6 h, blue, 100 Hz, 2.95 mW/mm^{2} |
Figure 4 |

*cc* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −0.7474299 0.1929174 | Tubb3, 6 h, red, 100 Hz |
Figure 4 |

*dd* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.2076411 −0.5625319 | Gfap, 6 h, blue, 100 Hz, 3.9 mW/mm^{2} |
Figure 5 |

*ee* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.6217416 0.6494064 | Gfap, 6 h, blue, 100 Hz, 2.95 mW/mm^{2} |
Figure 5 |

*ff* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.1985427 0.5754028 | Gfap, 6 h, red, 100 Hz |
Figure 5 |

*gg* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −3.635956 −2.350329 | Cx3r1, 6 h, blue, 100 Hz, 3.9 mW/mm^{2} |
Figure 5 |

*hh* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −3.53367205 −0.05504915 | Cx3cr1, 6 h, blue, 100 Hz, 2.95 mW/mm^{2} |
Figure 5 |

*ii* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.6631094 0.2506975 | Cx3cr1, 6 h, red, 100 Hz |
Figure 5 |

*jj* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −0.729 0.379 | Gapdh, 1 h, blue, 10 Hz, 3.9 mW/mm^{2} |
Table 2 |

*kk* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −0.319 0.621 | Gapdh, 6 h, blue, 10 Hz, 3.9 mW/mm^{2} |
Table 2 |

*ll* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.778 1.118 | Gapdh, 1 h, red, 10 Hz, 2.2 mW/mm^{2} |
Table 2 |

*mm* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.144 1.345 | Gapdh, 6 h, red, 10 Hz, 2.2 mW/mm^{2} |
Table 2 |

*nn* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.259 1.462 | Gapdh, 1 h, green, 10 Hz, 1.9 mW/mm^{2} |
Table 2 |

*oo* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −2.320 2.144 | Gapdh, 6 h, green, 10 Hz, 1.9 mW/mm^{2} |
Table 2 |

*pp* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.303 0.435 | Gapdh, 6 h, blue, 100 Hz, 3.9 mW/mm^{2} |
Table 2 |

*qq* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | −1.568 1.087 | Gapdh, 6 h, blue, 10 Hz, 1.95 mW/mm^{2} |
Table 2 |

*rr* | Normal | Two-sided Student’s *t* test on log fold changes, testing difference from log(1) | 0.063 0.510 | Gapdh, 6 h, red, 10 Hz, 2.2 mW/mm^{2} |
Table 2 |