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Research ArticleNew Research, Disorders of the Nervous System

Homeoprotein Neuroprotection of Embryonic Neuronal Cells

Stephanie E. Vargas Abonce, Mélanie Leboeuf, Alain Prochiantz and Kenneth L. Moya
eNeuro 26 August 2019, 6 (5) ENEURO.0061-19.2019; https://doi.org/10.1523/ENEURO.0061-19.2019
Stephanie E. Vargas Abonce
1Centre for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS UMR 7241/INSERM U1050, PSL Research University, Labex Memolife Paris Science et Lettres, 75005 Paris, France
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Mélanie Leboeuf
1Centre for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS UMR 7241/INSERM U1050, PSL Research University, Labex Memolife Paris Science et Lettres, 75005 Paris, France
2BrainEver, 75012 Paris, France
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Alain Prochiantz
1Centre for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS UMR 7241/INSERM U1050, PSL Research University, Labex Memolife Paris Science et Lettres, 75005 Paris, France
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Kenneth L. Moya
1Centre for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS UMR 7241/INSERM U1050, PSL Research University, Labex Memolife Paris Science et Lettres, 75005 Paris, France
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0061-19.2019
PubMed 
31451602
Published By 
Society for Neuroscience
History 
  • Received February 20, 2019
  • Revision received August 9, 2019
  • Accepted August 14, 2019
  • Published online August 26, 2019.
Copyright & Usage 
Copyright © 2019 Vargas Abonce et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Stephanie E. Vargas Abonce1,*,
  2. Mélanie Leboeuf1,2,*,
  3. Alain Prochiantz1 and
  4. Kenneth L. Moya1
  1. 1Centre for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS UMR 7241/INSERM U1050, PSL Research University, Labex Memolife Paris Science et Lettres, 75005 Paris, France
  2. 2BrainEver, 75012 Paris, France
  1. Correspondence should be addressed to Alain Prochiantz at Alain.prochiantz{at}college-de-france.fr or Kenneth L. Moya at Ken.moya{at}college-de-france.fr.
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Author contributions

  1. A.P. and K.L.M. designed research; S.E.V.A. and M.L. performed research; S.E.V.A., M.L., and K.L.M. analyzed data; S.E.V.A., M.L., A.P., and K.L.M. wrote the paper.

  2. ↵* S.E.V.A. and M. L. contributed equally to this work.

Disclosures

  • A.P and K.L.M. are listed on several patents for the use of homeoproteins for the treatment of neurodegenerative disease, and they are cofounders and hold shares in a company developing homeoproteins for therapeutic use. The authors declare no other competing financial interests.

  • This research was supported by a MemoLife Labex PhD Fellowship to S.E.V.A., Association Nationale de la Recherche et de la Technologie Grant Cifre/ANRT 2017/0488 to M.L., BrainEver, and HomeoSign Grant ERC2013-AdG 339379.

Funding

  • MemoLife Labex PhD fellowship

  • Association Nationale de la Recherche et de la Technologie (ANRT)

    Cifre/ANRT n{degree sign} 2017/0488
  • BrainEver

  • EC | European Research Council (ERC)

    HomeoSIGN ERC -2013-AdG n{degree sign}339379

Other Version

  • You are viewing the most recent version of this article.
  • previous version (August 26, 2019).

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Total63734031200
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Homeoprotein Neuroprotection of Embryonic Neuronal Cells
Stephanie E. Vargas Abonce, Mélanie Leboeuf, Alain Prochiantz, Kenneth L. Moya
eNeuro 26 August 2019, 6 (5) ENEURO.0061-19.2019; DOI: 10.1523/ENEURO.0061-19.2019

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Homeoprotein Neuroprotection of Embryonic Neuronal Cells
Stephanie E. Vargas Abonce, Mélanie Leboeuf, Alain Prochiantz, Kenneth L. Moya
eNeuro 26 August 2019, 6 (5) ENEURO.0061-19.2019; DOI: 10.1523/ENEURO.0061-19.2019
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Keywords

  • DNA damage
  • homeoprotein
  • neuroprotection
  • transcription factor

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