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Research ArticleNew Research, Development

Syntaphilin-Mediated Docking of Mitochondria at the Growth Cone Is Dispensable for Axon Elongation In Vivo

Tine Verreet, Cory J. Weaver, Hiromu Hino, Masahiko Hibi and Fabienne E. Poulain
eNeuro 3 September 2019, 6 (5) ENEURO.0026-19.2019; https://doi.org/10.1523/ENEURO.0026-19.2019
Tine Verreet
1Department of Biological Sciences, University of South Carolina, Columbia, South Carolina 29208
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Cory J. Weaver
1Department of Biological Sciences, University of South Carolina, Columbia, South Carolina 29208
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Hiromu Hino
2Laboratory of Organogenesis and Organ Function, Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Aichi, Japan
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Masahiko Hibi
2Laboratory of Organogenesis and Organ Function, Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Aichi, Japan
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Fabienne E. Poulain
1Department of Biological Sciences, University of South Carolina, Columbia, South Carolina 29208
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0026-19.2019
PubMed 
31481398
Published By 
Society for Neuroscience
History 
  • Received January 19, 2019
  • Revision received August 15, 2019
  • Accepted August 22, 2019
  • Published online September 3, 2019.
Copyright & Usage 
Copyright © 2019 Verreet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Tine Verreet1,
  2. Cory J. Weaver1,
  3. Hiromu Hino2,
  4. Masahiko Hibi2 and
  5. Fabienne E. Poulain1
  1. 1Department of Biological Sciences, University of South Carolina, Columbia, South Carolina 29208
  2. 2Laboratory of Organogenesis and Organ Function, Bioscience and Biotechnology Center, Nagoya University, Nagoya 464-8601, Aichi, Japan
  1. Correspondence should be addressed to Fabienne E. Poulain at Fpoulain{at}mailbox.sc.edu.
  • T. Verreet’s present address: VIB-KU Leuven Center for Brain & Disease Research, Department of Neurosciences, 3000 Leuven, Belgium.

  • M. Hibi’s present address: Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan.

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Author contributions

  1. Author contributions: F.E.P. designed research; T.V., C.J.W., and F.E.P. performed research; H.H. and M.H. contributed unpublished reagents/analytic tools; T.V., C.J.W., and F.E.P. analyzed data; T.V., C.J.W., and F.E.P. wrote the paper.

  • T. Verreet’s present address: VIB-KU Leuven Center for Brain & Disease Research, Department of Neurosciences, 3000 Leuven, Belgium.

  • M. Hibi’s present address: Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the National Institutes of Health (Grants R00-NS-083714 and R01-NS-109197 to F.E.P.), the University of South Carolina SmartState Center for Childhood Neurotherapeutics (to F.E.P.), the University of South Carolina (Aspire I Grant to T.V.), and the Belgian American Educational Foundation (postdoctoral fellowship to T.V.).

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    R00NS083714; R01NS109197
  • University of South Carolina (USC)

    SmartState Center for Childhood Neurotherapeutics; Aspire I
  • Belgian American Educational Foundation (B.A.E.F.)

    post-doctoral fellowship

Other Version

  • You are viewing the most recent version of this article.
  • previous version (September 03, 2019).

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Total48243631072
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Syntaphilin-Mediated Docking of Mitochondria at the Growth Cone Is Dispensable for Axon Elongation In Vivo
Tine Verreet, Cory J. Weaver, Hiromu Hino, Masahiko Hibi, Fabienne E. Poulain
eNeuro 3 September 2019, 6 (5) ENEURO.0026-19.2019; DOI: 10.1523/ENEURO.0026-19.2019

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Syntaphilin-Mediated Docking of Mitochondria at the Growth Cone Is Dispensable for Axon Elongation In Vivo
Tine Verreet, Cory J. Weaver, Hiromu Hino, Masahiko Hibi, Fabienne E. Poulain
eNeuro 3 September 2019, 6 (5) ENEURO.0026-19.2019; DOI: 10.1523/ENEURO.0026-19.2019
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Keywords

  • axon growth
  • confocal live imaging
  • mitochondria
  • Syntaphilin
  • visual system
  • zebrafish

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