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Research ArticleNew Research, Sensory and Motor Systems

PIM-Related Kinases Selectively Regulate Olfactory Sensations in Caenorhabditis elegans

Karunambigai S. Kalichamy, Kaisa Ikkala, Jonna Pörsti, Niina M. Santio, Joel Tuomaala, Sweta Jha, Carina I. Holmberg and Päivi J. Koskinen
eNeuro 6 August 2019, 6 (4) ENEURO.0003-19.2019; https://doi.org/10.1523/ENEURO.0003-19.2019
Karunambigai S. Kalichamy
1Section of Physiology and Genetics, Department of Biology, University of Turku, 20500 Turku, Finland
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  • ORCID record for Karunambigai S. Kalichamy
Kaisa Ikkala
1Section of Physiology and Genetics, Department of Biology, University of Turku, 20500 Turku, Finland
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Jonna Pörsti
1Section of Physiology and Genetics, Department of Biology, University of Turku, 20500 Turku, Finland
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Niina M. Santio
1Section of Physiology and Genetics, Department of Biology, University of Turku, 20500 Turku, Finland
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Joel Tuomaala
1Section of Physiology and Genetics, Department of Biology, University of Turku, 20500 Turku, Finland
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Sweta Jha
2Research Programs Unit, Translational Cancer Biology Program, University of Helsinki, 00290 Helsinki, Finland
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Carina I. Holmberg
2Research Programs Unit, Translational Cancer Biology Program, University of Helsinki, 00290 Helsinki, Finland
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Päivi J. Koskinen
1Section of Physiology and Genetics, Department of Biology, University of Turku, 20500 Turku, Finland
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0003-19.2019
PubMed 
31387876
Published By 
Society for Neuroscience
History 
  • Received January 4, 2019
  • Revision received July 12, 2019
  • Accepted July 18, 2019
  • Published online August 6, 2019.
Copyright & Usage 
Copyright © 2019 Kalichamy et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Karunambigai S. Kalichamy1,
  2. Kaisa Ikkala1,
  3. Jonna Pörsti1,
  4. Niina M. Santio1,
  5. Joel Tuomaala1,
  6. Sweta Jha2,
  7. Carina I. Holmberg2 and
  8. Päivi J. Koskinen1
  1. 1Section of Physiology and Genetics, Department of Biology, University of Turku, 20500 Turku, Finland
  2. 2Research Programs Unit, Translational Cancer Biology Program, University of Helsinki, 00290 Helsinki, Finland
  1. Correspondence should be addressed to Päivi J. Koskinen at paivi.koskinen{at}utu.fi.
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Author contributions

  1. Author contributions: K.S.K., C.I.H., and P.J.K. designed research; K.S.K., K.I., J.P., N.M.S., J.T., S.J., and P.J.K. performed research; K.S.K., K.I., J.P., N.M.S., J.T., S.J., and P.J.K. analyzed data; K.S.K., C.I.H., and P.J.K. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the Academy of Finland (Grants 297700 and 287040 to P.J.K., 297776 to C.I.H.) and Sigrid Jusélius Foundation (to C.I.H.). C. elegans strains were provided by the Caenorhabditis Genetics Center, which is funded by the NIH Office of Research Infrastructure Programs (P40 OD010440). We thank the Koskinen and Holmberg group members, P. Gallant, A. Berns, and J.I. Lee for helpful discussions, and S. N. Ho, M. Nonet, and P. Moreau for reagents.

Funding

  • Academy of Finland | Biotieteiden ja Ympäristön Tutkimuksen Toimikunta (Forskningsrådet för Biovetenskap och Miljö)

    297700; 297776
  • Academy of Finland | Terveyden Tutkimuksen Toimikunta (Forskningsrådet för Hälsa)

    287040
  • Sigrid Juselius Foundation

Other Version

  • You are viewing the most recent version of this article.
  • previous version (August 06, 2019).

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Aug 2019622198103
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Total 20251224542
Total9553226859
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PIM-Related Kinases Selectively Regulate Olfactory Sensations in Caenorhabditis elegans
Karunambigai S. Kalichamy, Kaisa Ikkala, Jonna Pörsti, Niina M. Santio, Joel Tuomaala, Sweta Jha, Carina I. Holmberg, Päivi J. Koskinen
eNeuro 6 August 2019, 6 (4) ENEURO.0003-19.2019; DOI: 10.1523/ENEURO.0003-19.2019

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PIM-Related Kinases Selectively Regulate Olfactory Sensations in Caenorhabditis elegans
Karunambigai S. Kalichamy, Kaisa Ikkala, Jonna Pörsti, Niina M. Santio, Joel Tuomaala, Sweta Jha, Carina I. Holmberg, Päivi J. Koskinen
eNeuro 6 August 2019, 6 (4) ENEURO.0003-19.2019; DOI: 10.1523/ENEURO.0003-19.2019
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Keywords

  • chemosensory neurons
  • chemotaxis
  • gustation
  • PIM kinases
  • olfaction
  • phosphorylation

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