Right Structural and Functional Reorganization in Four-Year-Old Children with Perinatal Arterial Ischemic Stroke Predict Language Production

Clément François; Pablo Ripollés; Laura Ferreri; Jordi Muchart; Joanna Sierpowska; Carme Fons; Jorgina Solé; Monica Rebollo; Robert J. Zatorre; Alfredo Garcia-Alix; Laura Bosch; Antoni Rodriguez-Fornells

doi:10.1523/ENEURO.0447-18.2019

Article Information

DOI

https://doi.org/10.1523/ENEURO.0447-18.2019

PubMed

31383726

Published By

Society for Neuroscience

History

Received November 12, 2018
Revision received April 24, 2019
Accepted June 3, 2019
Published online August 5, 2019.

Copyright © 2019 François et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

Clément François¹,²,^*,
Pablo Ripollés³,^*,
Laura Ferreri¹,²,
Jordi Muchart⁴,
Joanna Sierpowska⁵,⁶,
Carme Fons⁴,
Jorgina Solé²,
Monica Rebollo⁴,
Robert J. Zatorre⁸,
Alfredo Garcia-Alix⁴,⁷,⁹,
Laura Bosch²,¹⁰ and
Antoni Rodriguez-Fornells¹,²,¹¹

¹Cognition and Brain Plasticity Group, Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Barcelona 08907, Spain
²Department of Cognition, Development and Educational Science, University of Barcelona, Barcelona 08035, Spain
³Poeppel Lab, Department of Psychology, New York University, NY 10003
⁴Institut de Recerca Sant Joan de Déu. Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona 08950, Spain
⁵Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6525 HR, Nijmegen, The Netherlands
⁶Department of Medical Psychology, Radboud University Medical Center, Nijmegen, The Netherlands
⁷Service of Genetic and Molecular Medicine, Hospital Sant Joan de Déu, Barcelona 08950, Spain
⁸Cognitive Neuroscience Unit, Montreal Neurological Institute, McGill University, Montreal H3A 2B4, Canada
⁹Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), U724, Madrid, Spain
¹⁰Institute of Neuroscience (UBNeuro), University of Barcelona, Barcelona, 08035, Spain
¹¹Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, 08010, Spain

Correspondence should be addressed to Antoni Rodriguez-Fornells at antoni.rodriguez{at}icrea.cat or Laura Bosch at laurabosch{at}ub.edu.

L. Ferreri's present address: Laboratoire d’Etude des Mécanismes Cognitifs, Université Lumière Lyon 2, 69676 Lyon, France.

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Author contributions

Author contributions: C. François, P.R., R.J.Z., A.G.A., L.B., and A.R.-F. designed research; C. François, P.R., and J. Solé performed research; C. François, P.R., L.F., and J. Sierpowska analyzed data; C. François, P.R., L.B., and A.R.-F. wrote the paper; J.M., C. Fons, M.R., and A.G.A. contributed unpublished reagents/analytic tools.

L. Ferreri's present address: Laboratoire d’Etude des Mécanismes Cognitifs, Université Lumière Lyon 2, 69676 Lyon, France.

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Disclosures

The authors declare no competing financial interests.
This work was partially supported by the “Plan Nacional de I+D+I and ISCIII, Subdirección General de Evaluación y Fomento de la Investigación Sanitaria” Project PI15/00846 (to A.G-A); the European Regional Development Fund (FEDER “a Way to Build Europe”); the Department of Health of the Generalitat de Catalunya “Acció instrumental d'incorporació de científics i tecnòlegs” Grant SLT002/16/00390 (to C.Fr.); a grant from the Bial Foundation (A.R.F.); and the Spanish MINECO Project PSI 2014-55105P (to L.B.).
↵* C.F. and P.R. are co-first authors.