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Research ArticleNew Research, Disorders of the Nervous System

Cerebellar Neurodegeneration and Neuronal Circuit Remodeling in Golgi pH Regulator-Deficient Mice

Yu-shin Sou, Soichiro Kakuta, Yuji Kamikubo, Kazue Niisato, Takashi Sakurai, Laxmi Kumar Parajuli, Isei Tanida, Hiromitsu Saito, Noboru Suzuki, Kenji Sakimura, Yusuke Maeda, Taroh Kinoshita, Yasuo Uchiyama and Masato Koike
eNeuro 22 May 2019, 6 (3) ENEURO.0427-18.2019; https://doi.org/10.1523/ENEURO.0427-18.2019
Yu-shin Sou
1Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan
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Soichiro Kakuta
2Laboratory of Morphology and Image Analysis, Research Support Center, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan
3Department of Cellular and Molecular Neuropathology, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan
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Yuji Kamikubo
4Department of Pharmacology, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan
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  • ORCID record for Yuji Kamikubo
Kazue Niisato
4Department of Pharmacology, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan
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Takashi Sakurai
4Department of Pharmacology, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan
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Laxmi Kumar Parajuli
1Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan
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Isei Tanida
1Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan
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Hiromitsu Saito
5Functional Genomics Institute, Life Science Research Center, Mie University, Tsu, Mie 514-8507, Japan
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Noboru Suzuki
5Functional Genomics Institute, Life Science Research Center, Mie University, Tsu, Mie 514-8507, Japan
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Kenji Sakimura
6Department of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585, Japan
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Yusuke Maeda
7Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan
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Taroh Kinoshita
7Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan
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  • ORCID record for Taroh Kinoshita
Yasuo Uchiyama
3Department of Cellular and Molecular Neuropathology, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan
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Masato Koike
1Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, Bunkyo, Tokyo 113-8421, Japan
8Advanced Research Institute for Health Science, Juntendo University, Bunkyo, Tokyo 113-8421, Japan
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Cerebellar Neurodegeneration and Neuronal Circuit Remodeling in Golgi pH Regulator-Deficient Mice
Yu-shin Sou, Soichiro Kakuta, Yuji Kamikubo, Kazue Niisato, Takashi Sakurai, Laxmi Kumar Parajuli, Isei Tanida, Hiromitsu Saito, Noboru Suzuki, Kenji Sakimura, Yusuke Maeda, Taroh Kinoshita, Yasuo Uchiyama, Masato Koike
eNeuro 22 May 2019, 6 (3) ENEURO.0427-18.2019; DOI: 10.1523/ENEURO.0427-18.2019

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Cerebellar Neurodegeneration and Neuronal Circuit Remodeling in Golgi pH Regulator-Deficient Mice
Yu-shin Sou, Soichiro Kakuta, Yuji Kamikubo, Kazue Niisato, Takashi Sakurai, Laxmi Kumar Parajuli, Isei Tanida, Hiromitsu Saito, Noboru Suzuki, Kenji Sakimura, Yusuke Maeda, Taroh Kinoshita, Yasuo Uchiyama, Masato Koike
eNeuro 22 May 2019, 6 (3) ENEURO.0427-18.2019; DOI: 10.1523/ENEURO.0427-18.2019
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Keywords

  • cerebellar circuit
  • Golgi apparatus
  • Golgi fragmentation
  • Golgi pH regulator
  • neurodegeneration
  • Purkinje cell

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