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Research ArticleNew Research, Cognition and Behavior

Plasticity of NMDA Receptors at Ventral Hippocampal Synapses in the Infralimbic Cortex Regulates Cued Fear

Omar Soler-Cedeño, Orlando Torres-Rodríguez, Faviola Bernard, Lizette Maldonado, Anixa Hernández and James T. Porter
eNeuro 14 March 2019, 6 (2) ENEURO.0354-18.2019; DOI: https://doi.org/10.1523/ENEURO.0354-18.2019
Omar Soler-Cedeño
1Department of Basic Sciences, Ponce Research Institute, Ponce Health Sciences University, Ponce, PR 00732
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  • ORCID record for Omar Soler-Cedeño
Orlando Torres-Rodríguez
1Department of Basic Sciences, Ponce Research Institute, Ponce Health Sciences University, Ponce, PR 00732
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Faviola Bernard
2Department of Biology, University of Puerto Rico-Ponce, Ponce, PR 00734
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Lizette Maldonado
1Department of Basic Sciences, Ponce Research Institute, Ponce Health Sciences University, Ponce, PR 00732
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Anixa Hernández
1Department of Basic Sciences, Ponce Research Institute, Ponce Health Sciences University, Ponce, PR 00732
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James T. Porter
1Department of Basic Sciences, Ponce Research Institute, Ponce Health Sciences University, Ponce, PR 00732
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0354-18.2019
PubMed 
30923737
Published By 
Society for Neuroscience
History 
  • Received September 7, 2018
  • Revision received February 4, 2019
  • Accepted February 10, 2019
  • Published online March 14, 2019.
Copyright & Usage 
Copyright © 2019 Soler-Cedeño et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Omar Soler-Cedeño1,
  2. Orlando Torres-Rodríguez1,
  3. Faviola Bernard2,
  4. Lizette Maldonado1,
  5. Anixa Hernández1 and
  6. James T. Porter1
  1. 1Department of Basic Sciences, Ponce Research Institute, Ponce Health Sciences University, Ponce, PR 00732
  2. 2Department of Biology, University of Puerto Rico-Ponce, Ponce, PR 00734
  1. Correspondence should be addressed to James T. Porter at jporter{at}psm.edu
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Author contributions

  1. Author contributions: O.S.-C., O.T.-R., and J.T.P. designed research; O.S.-C., O.T.-R., F.B., L.M., and A.H. performed research; O.S.-C., O.T.-R., F.B., L.M., A.H., and J.T.P. analyzed data; O.S.-C., O.T.-R., and J.T.P. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the Research Centers in Minority Institutions BRAIN and MAGIC Cores Grant NIMHHD G12 MD007579-27, the Ponce Health Sciences University and University of Puerto Rico-Ponce Research Initiative for Scientific Enhancement Programs R25 GM082406 and R25 GM096955, and National Institutes of Health Grants R15 MH101700 and F31 MH106288.

Funding

  • HHS | NIH | National Institute on Minority Health and Health Disparities (NIMHD)

    G12 MD007579
  • HHS | NIH | National Institute of General Medical Sciences (NIGMS)

    R25 GM082406; R25 GM096955
  • HHS | NIH | National Institute of Mental Health (NIMH)

    R15 MH101700; F31 MH106288

Other Version

  • You are viewing the most recent version of this article.
  • previous version (March 14, 2019).

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Mar 20191255113183
Apr 201954121153
May 2019909421
Jun 2019287528
Jul 2019216722
Aug 2019265422
Oct 2019167320
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Total 20191995895381
Jan 20201012914
Feb 20201416623
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May 202024118
Jun 202053512
Jul 2020513534
Aug 202026213
Sep 202043118
Oct 202086928
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Total 202074928245
Jan 202146925
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Jun 202126114
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Total 202129719247
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Feb 20226569
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Jul 202217015
Aug 202213712
Sep 202212920
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Total 202228619181
Jan 20233309
Feb 202304514
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Apr 20233528
May 202313714
Jun 202354010
Jul 202324523
Aug 202386147
Sep 20232264
Total 202324380146
Total215035411200
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Plasticity of NMDA Receptors at Ventral Hippocampal Synapses in the Infralimbic Cortex Regulates Cued Fear
Omar Soler-Cedeño, Orlando Torres-Rodríguez, Faviola Bernard, Lizette Maldonado, Anixa Hernández, James T. Porter
eNeuro 14 March 2019, 6 (2) ENEURO.0354-18.2019; DOI: 10.1523/ENEURO.0354-18.2019

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Plasticity of NMDA Receptors at Ventral Hippocampal Synapses in the Infralimbic Cortex Regulates Cued Fear
Omar Soler-Cedeño, Orlando Torres-Rodríguez, Faviola Bernard, Lizette Maldonado, Anixa Hernández, James T. Porter
eNeuro 14 March 2019, 6 (2) ENEURO.0354-18.2019; DOI: 10.1523/ENEURO.0354-18.2019
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Keywords

  • fear conditioning
  • fear extinction
  • NMDA receptor
  • prefrontal cortex
  • PTSD
  • ventral hippocampus

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