Article Information
- Received June 28, 2018
- Revision received January 15, 2019
- Accepted January 18, 2019
- Published online January 31, 2019.
Author Information
- Marietta Zille1,2,3,4,
- Amit Kumar1,2,
- Nandini Kundu1,2,
- Megan W. Bourassa1,2,
- Victor S. C. Wong1,2,
- Dianna Willis1,2,
- Saravanan S. Karuppagounder1,2 and
- Rajiv R. Ratan1,2
- 1Burke Neurological Institute, White Plains, New York 10605
- 2Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York 10065
- 3Fraunhofer Research Institution for Marine Biotechnology and Cell Technology and Institute for Medical and Marine Biotechnology, University of Lübeck, Lübeck, 23562, Germany
- 4Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, 23562, Germany
- Correspondence should be addressed to Rajiv R. Ratan at rrr2001{at}med.cornell.edu.
Author contributions
Author contributions: M.Z. and R.R.R. designed all experiments; M.Z. performed all experiments except Scriptaid experiments in erastin-induced cell death in PCN, which were performed by M.W.B., SH-SY5Y and Hep3B experiments, which were performed by A.K., DRG experiments, which were performed by V.S.C.W. and D.W., and gene expression experiments, which were performed by S.S.K. and N.K.; M.Z. analyzed the data, performed the statistical analysis, and graphical artwork; M.Z. and R.R.R. wrote and edited the paper; all authors discussed the results and commented on the paper.
Disclosures
The authors declare no competing financial interests.
This work was supported by Grant DFG Zi 1613/1-1 (Project #298966395) to M.Z. from the German Research Foundation, and funding from the Sheldon G. and Dr. Miriam Adelson Medical Research Foundation and the Sperling Center for Hemorrhagic Stroke Recovery to R.R.R. The rabbit anti-phospho-S166 RIP1 antibody was provided by Peter J. Gough, John Bertin, and Joshua Finger, (GlaxoSmithKline).
Funding
German Research Foundation
DFG Zi 1613/1-1 Project number: 298966395Dr. Miriam and Sheldon G. Adelson Medical Research Foundation (AMRF)
Sperling Center for Hemorrhagic Stroke Recovery
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