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Research ArticleConfirmation, Disorders of the Nervous System

Large-Scale 3–5 Hz Oscillation Constrains the Expression of Neocortical Fast Ripples in a Mouse Model of Mesial Temporal Lobe Epilepsy

Laurent Sheybani, Pieter van Mierlo, Gwénaël Birot, Christoph M. Michel and Charles Quairiaux
eNeuro 5 February 2019, 6 (1) ENEURO.0494-18.2019; https://doi.org/10.1523/ENEURO.0494-18.2019
Laurent Sheybani
1Functional Brain Mapping Laboratory, Department of Fundamental Neuroscience, University of Geneva, 1202 Geneva, Switzerland
2Neurology Clinic, Department of Clinical Neuroscience, University Hospital Geneva, 1206 Geneva, Switzerland
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Pieter van Mierlo
1Functional Brain Mapping Laboratory, Department of Fundamental Neuroscience, University of Geneva, 1202 Geneva, Switzerland
3Medical Image and Signal Processing Group, Ghent University, 9052 Ghent, Belgium
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Gwénaël Birot
1Functional Brain Mapping Laboratory, Department of Fundamental Neuroscience, University of Geneva, 1202 Geneva, Switzerland
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Christoph M. Michel
1Functional Brain Mapping Laboratory, Department of Fundamental Neuroscience, University of Geneva, 1202 Geneva, Switzerland
4Center for Biomedical Imaging (CIBM), 1015 Lausanne, Switzerland
5Center for Biomedical Imaging (CIBM), Geneva, Switzerland
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Charles Quairiaux
1Functional Brain Mapping Laboratory, Department of Fundamental Neuroscience, University of Geneva, 1202 Geneva, Switzerland
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0494-18.2019
PubMed 
30783615
Published By 
Society for Neuroscience
History 
  • Received December 18, 2018
  • Revision received January 21, 2019
  • Accepted January 24, 2019
  • Published online February 5, 2019.
Copyright & Usage 
Copyright © 2019 Sheybani et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Laurent Sheybani1,2,
  2. Pieter van Mierlo1,3,
  3. Gwénaël Birot1,
  4. Christoph M. Michel1,4,5 and
  5. Charles Quairiaux1
  1. 1Functional Brain Mapping Laboratory, Department of Fundamental Neuroscience, University of Geneva, 1202 Geneva, Switzerland
  2. 2Neurology Clinic, Department of Clinical Neuroscience, University Hospital Geneva, 1206 Geneva, Switzerland
  3. 3Medical Image and Signal Processing Group, Ghent University, 9052 Ghent, Belgium
  4. 4Center for Biomedical Imaging (CIBM), 1015 Lausanne, Switzerland
  5. 5Center for Biomedical Imaging (CIBM), Geneva, Switzerland
  1. Correspondence should be addressed to Laurent Sheybani at laurent.sheybani{at}unige.ch.
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Author contributions

  1. Author contributions: L.S., C.M.M., and C.Q. designed research; L.S. performed research; L.S., P.v.M., G.B., and C.Q. analyzed data; L.S. and C.Q. wrote the paper.

Disclosures

  • The authors declare no competing financial interests. L.S. was supported by the Swiss National Science Foundation (Grant 323530-158125). G.B. was supported by the Swiss National Science Foundation (Grant 140332). C.M. was supported by the Swiss National Science Foundation (Grant 320030-159705), by the National Center of Competence in Research (NCCR) “SYNAPSY,” and by the Center for Biomedical Imaging (CIBM) from Geneva and Lausanne. C.Q. was supported by the Fondation Ernst et Lucie Schmidheiny and by the Swiss League Against Epilepsy.

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Jan 20261511020
Feb 20261117717
Mar 20261314825
Apr 2026105939
Total 202649494101
Total129564021275
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Large-Scale 3–5 Hz Oscillation Constrains the Expression of Neocortical Fast Ripples in a Mouse Model of Mesial Temporal Lobe Epilepsy
Laurent Sheybani, Pieter van Mierlo, Gwénaël Birot, Christoph M. Michel, Charles Quairiaux
eNeuro 5 February 2019, 6 (1) ENEURO.0494-18.2019; DOI: 10.1523/ENEURO.0494-18.2019

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Large-Scale 3–5 Hz Oscillation Constrains the Expression of Neocortical Fast Ripples in a Mouse Model of Mesial Temporal Lobe Epilepsy
Laurent Sheybani, Pieter van Mierlo, Gwénaël Birot, Christoph M. Michel, Charles Quairiaux
eNeuro 5 February 2019, 6 (1) ENEURO.0494-18.2019; DOI: 10.1523/ENEURO.0494-18.2019
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Keywords

  • cross-frequency coupling
  • epilepsy
  • epileptic network
  • fast-ripples
  • oscillation

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