Article Information
- Received November 20, 2018
- Revision received January 15, 2019
- Accepted January 15, 2019
- Published online February 13, 2019.
Author Information
- Ekaterina Zhurakovskaya1,*,
- Juuso Leikas2,*,
- Tiina Pirttimäki1,
- Francesc Casas Mon2,
- Mikko Gynther2,
- Rubin Aliev3,4,
- Tomi Rantamäki5,
- Heikki Tanila1,
- Markus M. Forsberg2,
- Olli Gröhn1,
- Jaakko Paasonen1,† and
- Aaro J. Jalkanen2,†
- 1A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, FI-70211, Finland
- 2School of Pharmacy, University of Eastern Finland, Kuopio, FI-70211, Finland
- 3Moscow Institute of Physics and Technology, 117303, Moscow, Russia
- 4Institute of Theoretical and Experimental Biophysics, 142292, Puschino, Russia
- 5Laboratory of Neurotherapeutics, Division of Pharmacology and Pharmacotherapeutics, Faculty of Pharmacy, University of Helsinki, Helsinki, FI-00790, Finland
- Correspondence should be addressed to Aaro J. Jalkanen at Aaro.Jalkanen{at}uef.fi.
Author contributions
E.Z., J.L., T.P., M.M.F., O.G., J.P., and A.J.J. designed research; E.Z., J.L., F.C.M., M.G., J.P., and A.J.J. performed research; E.Z., J.L., M.G., J.P., and A.J.J. analyzed data; E.Z., J.L., T.P., M.G., R.A., T.R., H.T., M.M.F., O.G., J.P., and A.J.J. wrote the paper.
↵* E.Z. and J.L. contributed equally to this work.
↵† J.P. and A.J.J. contributed equally to this work as co-senior authors.
Disclosures
The authors declare no competing financial interests.
This work was supported by Emil Aaltonen foundation (T.P.), Finnish Academy of Science and Letters (E.Z.), and the Academy of Finland (O.G.). The funding sources had no role in study design; in the collection, analysis and interpretation of data; in the writing of the report; or in the decision to submit the article for publication. We thank Kalle Voutilainen for help with the animal experiments and DA assay, Maarit Pulkkinen for technical assistance in fMRI experiments, Jaana Leskinen for help with biochemical assays, Raimo Salo for valuable advice in data analysis, and Dr. Ewen MacDonald for the linguistic revision of this paper.
Funding
Emil Aaltosen Säätiö (Emil Aaltonen Foundation)
Suomalainen Tiedeakatemia (Finnish Academy of Science and Letters)
Suomen Akatemia (Academy of Finland)
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