Article Figures & Data
Figures
- Figure 1
Schematic diagram of all the treatments in each experiment.
- Figure 2
E2 in the DLS or EB, subcutaneously, potentiates DA release following AMPH injections. E2 was dissolved in Ringer’s solution and was infused into the DLS via reverse microdialysis. *indicates a significant difference between rats treated with E2 or EB and control rats.
- Figure 3
ICI infused into the DLS reduces E2-induced DA potentiation following AMPH injections. *indicates a significant difference between rats treated with ICI and control rats.
- Figure 4
MPEP reduces E2-induced DA potentiation following AMPH injections. *indicates a significant difference between rats treated with MPEP and control rats.
- Figure 5
Neither ICI or MPEP influences DA release in the DLS when estradiol was not administered. These rats were ovariectomized and were not given EB injections or E2 infusions.
Tables
- Table 1
: Comparisons of DA release in response to AMPH among rats with varying pretreatments in Experiments 1–3
ANOVA tests comparing rats treated with EB, E2, and Vehicle in Experiment 1 Time post-AMPH, min 10 20 30 40 F value F(2,25) = 1.853 F(2,25) = 4.433 F(2,25) = =5.045 F(2,25) = 3.939 p value 0.178 0.023 0.014 0.033 Planned contrast tests Time post-AMPH, min 10 20 30 40 p Value, Control vs EB NA 0.037 0.083 0.233 p Value, Control vs E2 NA 0.013 0.005 0.010 Mann-Whitney U tests comparing rats treated with EB and ICI+EB in Experiment 2 Time post-AMPH, min 10 20 30 40 U 14.000 14.000 12.000 9.000 p value 0.034 0.034 0.021 0.009 Independent tests comparing rats treated with E2 and E2+MPEP in Experiment 3 Time post-AMPH, min 10 20 30 40 t value t(16) = 1.410 t(16) = 2.790 t(16) = 2.232 t(16) = 1.993 p value 0.178 0.013 0.040 0.064 Values in bold indicate significant differences.
In this issue
