Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleNew Research, Cognition and Behavior

Aerobic Glycolysis Is Required for Spatial Memory Acquisition But Not Memory Retrieval in Mice

Richard A. Harris, Asad Lone, Heeseung Lim, Francisco Martinez, Ariel K. Frame, Timothy J. Scholl and Robert C. Cumming
eNeuro 11 February 2019, 6 (1) ENEURO.0389-18.2019; https://doi.org/10.1523/ENEURO.0389-18.2019
Richard A. Harris
1Department of Biology, University of Western Ontario, London, Ontario N6A 5B7, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Asad Lone
1Department of Biology, University of Western Ontario, London, Ontario N6A 5B7, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Heeseung Lim
2Department of Medical Biophysics, University of Western Ontario, London, Ontario N6A 5C1, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Francisco Martinez
3Robarts Research Institute, University of Western Ontario, London, Ontario N6A 3K7, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ariel K. Frame
1Department of Biology, University of Western Ontario, London, Ontario N6A 5B7, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ariel K. Frame
Timothy J. Scholl
2Department of Medical Biophysics, University of Western Ontario, London, Ontario N6A 5C1, Canada
3Robarts Research Institute, University of Western Ontario, London, Ontario N6A 3K7, Canada
4 Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Timothy J. Scholl
Robert C. Cumming
1Department of Biology, University of Western Ontario, London, Ontario N6A 5B7, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Robert C. Cumming
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0389-18.2019
PubMed 
30809587
Published By 
Society for Neuroscience
History 
  • Received October 3, 2018
  • Revision received January 23, 2019
  • Accepted January 26, 2019
  • Published online February 11, 2019.
Copyright & Usage 
Copyright © 2019 Harris et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Richard A. Harris1,*,
  2. Asad Lone1,*,
  3. Heeseung Lim2,
  4. Francisco Martinez3,
  5. Ariel K. Frame1,
  6. Timothy J. Scholl2,3,4 and
  7. Robert C. Cumming1
  1. 1Department of Biology, University of Western Ontario, London, Ontario N6A 5B7, Canada
  2. 2Department of Medical Biophysics, University of Western Ontario, London, Ontario N6A 5C1, Canada
  3. 3Robarts Research Institute, University of Western Ontario, London, Ontario N6A 3K7, Canada
  4. 4 Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada
  1. Correspondence should be addressed to Robert C. Cumming at rcummin5{at}uwo.ca.
View Full Text

Author contributions

  1. R.A.H., T.J.S., and R.C.C. designed research; R.A.H., A.L., H.L., F.M., and A.K.F. performed research; R.A.H., A.L., and R.C.C. analyzed data; R.A.H., A.L., and R.C.C. wrote the paper.

  2. ↵* R.A.H. and A.L. contributed equally to this work.

Disclosures

  • The authors declare no competing financial interests.

  • This research was supported by Natural Sciences and Engineering Research Council of Canada Grants 355803-2013 (R.C.C.) and 06338-2017 (T.J.S.), Scottish Rite Charitable Foundation Grant 11103 (R.C.C.), Canada Foundation for Innovation Grant 22167 (R.C.C.), and Canadian Consortium on Neurodegeneration in Aging Grant 137794 (R.C.C.).

Funding

  • Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (NSERC)

    355803-2013; 06338-2017
  • Canadian Consortium on Neurodegeneration in Aging

    137794
  • Scottish Rite Charitable Foundation of Canada (SRCFC)

    11103
  • Canada Foundation for Innovation (CFI)

    22167

Other Version

  • You are viewing the most recent version of this article.
  • previous version (February 11, 2019).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2025-12-09
to
E.g., 2025-12-09

Article usage: February 2019 to December 2025

AbstractFullPdf
Feb 201971191104
Mar 201930833650
Apr 20195422219
May 20193320829
Jun 20192417316
Jul 20191626026
Aug 20191542226
Oct 20191137716
Nov 20191225417
Dec 2019917217
Total 201911932515320
Jan 202069022
Feb 202096327
Mar 202068128
May 202046529
Jun 202028621
Jul 202035631
Aug 202064233
Sep 202034718
Oct 202026125
Nov 202026512
Dec 202099324
Total 202052749270
Jan 202149830
Feb 202115821
Mar 202138416
Apr 202116116
May 202157819
Jun 20213508
Jul 202115717
Aug 202128431
Sep 202116923
Oct 202147732
Nov 202136532
Dec 202128028
Total 202130861273
Jan 202247517
Feb 202225418
Mar 202243813
Apr 202214214
May 202206823
Jun 202206723
Jul 202225713
Aug 202245222
Sep 202203418
Oct 202254924
Nov 202256218
Dec 202245516
Total 202231653219
Jan 202325721
Feb 202305912
Mar 20230438
Apr 202305011
May 202316423
Jun 202326019
Jul 202367027
Aug 2023105740
Sep 202394919
Oct 202336016
Nov 2023104615
Dec 202367424
Total 202349689235
Jan 202446419
Feb 202410508
Mar 202495621
Apr 20241912227
May 2024109420
Jun 202486614
Jul 202495827
Aug 202475320
Sep 202425816
Oct 202465615
Nov 202426320
Dec 202466516
Total 202492805223
Jan 2025136534
Feb 202526814
Mar 202546322
Apr 202545915
May 20251568
Jun 202566019
Jul 202597531
Aug 202546418
Sep 2025910422
Oct 20251115028
Nov 20251211423
Dec 20251242
Total 202576902236
Total152371741776
Back to top

In this issue

eneuro: 6 (1)
eNeuro
Vol. 6, Issue 1
January/February 2019
  • Table of Contents
  • Index by author
  • Ed Board (PDF)
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Aerobic Glycolysis Is Required for Spatial Memory Acquisition But Not Memory Retrieval in Mice
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Aerobic Glycolysis Is Required for Spatial Memory Acquisition But Not Memory Retrieval in Mice
Richard A. Harris, Asad Lone, Heeseung Lim, Francisco Martinez, Ariel K. Frame, Timothy J. Scholl, Robert C. Cumming
eNeuro 11 February 2019, 6 (1) ENEURO.0389-18.2019; DOI: 10.1523/ENEURO.0389-18.2019

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Aerobic Glycolysis Is Required for Spatial Memory Acquisition But Not Memory Retrieval in Mice
Richard A. Harris, Asad Lone, Heeseung Lim, Francisco Martinez, Ariel K. Frame, Timothy J. Scholl, Robert C. Cumming
eNeuro 11 February 2019, 6 (1) ENEURO.0389-18.2019; DOI: 10.1523/ENEURO.0389-18.2019
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
    • Synthesis
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • aerobic glycolysis
  • lactate
  • magnetic resonance spectroscopy
  • memory
  • metabolism
  • synaptic plasticity

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

New Research

  • A Very Fast Time Scale of Human Motor Adaptation: Within Movement Adjustments of Internal Representations during Reaching
  • TrkB Signaling Influences Gene Expression in Cortistatin-Expressing Interneurons
  • Optogenetic Activation of β-Endorphin Terminals in the Medial Preoptic Nucleus Regulates Female Sexual Receptivity
Show more New Research

Cognition and Behavior

  • Pairing mouse social and aversive stimuli across sexes does not produce social aversion in females
  • In-vivo analysis of medial perforant path-evoked excitation and inhibition in dentate granule cells
  • Altered Dopamine Signaling in Extinction-Deficient Mice
Show more Cognition and Behavior

Subjects

  • Cognition and Behavior
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2025 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.