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Research ArticleNew Research, Neuronal Excitability

The Differences in Local Translatome across Distinct Neuron Types Is Mediated by Both Baseline Cellular Differences and Post-transcriptional Mechanisms

Rebecca Ouwenga, Allison M. Lake, Shivani Aryal, Tomas Lagunas Jr and Joseph D. Dougherty
eNeuro 26 December 2018, 5 (6) ENEURO.0320-18.2018; https://doi.org/10.1523/ENEURO.0320-18.2018
Rebecca Ouwenga
1Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, Missouri 63110
2Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110
3Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110
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Allison M. Lake
2Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110
3Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110
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Shivani Aryal
1Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, Missouri 63110
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Tomas Lagunas Jr
1Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, Missouri 63110
2Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110
3Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110
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Joseph D. Dougherty
2Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110
3Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110
4Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, Missouri 63110
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eneuro: 5 (6)
eNeuro
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November/December 2018
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The Differences in Local Translatome across Distinct Neuron Types Is Mediated by Both Baseline Cellular Differences and Post-transcriptional Mechanisms
Rebecca Ouwenga, Allison M. Lake, Shivani Aryal, Tomas Lagunas Jr, Joseph D. Dougherty
eNeuro 26 December 2018, 5 (6) ENEURO.0320-18.2018; DOI: 10.1523/ENEURO.0320-18.2018

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The Differences in Local Translatome across Distinct Neuron Types Is Mediated by Both Baseline Cellular Differences and Post-transcriptional Mechanisms
Rebecca Ouwenga, Allison M. Lake, Shivani Aryal, Tomas Lagunas Jr, Joseph D. Dougherty
eNeuro 26 December 2018, 5 (6) ENEURO.0320-18.2018; DOI: 10.1523/ENEURO.0320-18.2018
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Keywords

  • GABAergic interneurons
  • layer 5 pyramidal neurons
  • local translation
  • synaptoneurosomes
  • SynapTRAP
  • TRAP

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