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History
- Received August 6, 2018
- Revision received September 17, 2018
- Accepted October 5, 2018
- Published online October 22, 2018.
Copyright & Usage
Copyright © 2018 Ito et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
Author Information
- Shuhei Ito1,2,
- Narihito Nagoshi1,2,
- Osahiko Tsuji2,
- Shinsuke Shibata1,
- Munehisa Shinozaki1,
- Soya Kawabata1,2,
- Kota Kojima1,2,
- Kaori Yasutake1,
- Tomoko Hirokawa3,
- Morio Matsumoto2,
- Kohtaro Takei3,
- Masaya Nakamura2 and
- Hideyuki Okano1
- 1Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan
- 2Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan
- 3Molecular Medical Bioscience Laboratory, Yokohama City University Graduate School of Medical Life Science, Yokohama 230-0045, Japan
- Correspondence should be addressed to either of the following: Masaya Nakamura, Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan, E-mail: masa{at}keio.jp; or Hideyuki Okano, Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan, E-mail: hidokano{at}a2.keio.jp.
Author contributions
Author contributions: S.I., S.K., M.N., and H.O. designed research; S.I., N.N., O.T., S.S., M.S., S.K., K.K, K.Y., T.H., K.T., and M.M. performed research; K.T. contributed unpublished reagents/analytic tools; S.I. analyzed data; S.I., N.N., M.N., and H.O. wrote the paper.
Disclosures
H.O. serves as a paid scientific advisor to SanBio Co. Ltd and K Phama Inc. All other authors declare no competing financial interests.
This work was supported by the Japan Agency for Medical Research and Development (AMED) Grant 15bm0204001h0003 (to H.O. and M.N.) and in part by The General Insurance Association of Japan medical research grant on traffic accidents 16-1-20.
Funding
Japan Agency for Medical Research and Development (AMED)
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