Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleNew Research, Disorders of the Nervous System

Adaptation and Inhibition Control Pathological Synchronization in a Model of Focal Epileptic Seizure

Anatoly Buchin, Cliff C. Kerr, Gilles Huberfeld, Richard Miles and Boris Gutkin
eNeuro 13 September 2018, 5 (5) ENEURO.0019-18.2018; https://doi.org/10.1523/ENEURO.0019-18.2018
Anatoly Buchin
1University of Washington, Department of Physiology and Biophysics (United States, Seattle), 1959 NE Pacific St, 98195
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Anatoly Buchin
Cliff C. Kerr
2University of Sydney, School of Physics (Australia, Sydney), Physics Rd, NSW 2006
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gilles Huberfeld
3Sorbonne Université-UPMC, Pitié-Salpêtrière Hô, Neurophysiology Department (France, Paris), 47-83 Boulevard de l’Hôpital, 75013
4Institut national de la santé et de la recherche médicale Unit 1129 “Infantile Epilepsies and Brain Plasticity”, Paris Descartes University, Sorbonne Paris Cité University group, (France, Paris), 149 rue de Sévres 75015
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Gilles Huberfeld
Richard Miles
5Brain and Spine Institute, Cortex and Epilepsie Group (France, Paris), 47 Boulevard Hôpital, 75013
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Boris Gutkin
6Paris Sciences & Lettres Research University, Laboratoire des Neurosciences Cognitives, Group for Neural Theory (France, Paris), 29, rue d'Ulm, 75005 France
7National Research University Higher School of Economics, Center for Cognition and Decision Making (Russia, Moscow), 20 Myasnitskaya, 109316
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Boris Gutkin
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0019-18.2018
PubMed 
30302390
Published By 
Society for Neuroscience
History 
  • Received January 10, 2018
  • Revision received June 7, 2018
  • Accepted June 7, 2018
  • Published online September 13, 2018.
Copyright & Usage 
Copyright © 2018 Buchin et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Anatoly Buchin1,*,
  2. Cliff C. Kerr2,
  3. Gilles Huberfeld3,4,
  4. Richard Miles5 and
  5. Boris Gutkin6,7
  1. 1University of Washington, Department of Physiology and Biophysics (United States, Seattle), 1959 NE Pacific St, 98195
  2. 2University of Sydney, School of Physics (Australia, Sydney), Physics Rd, NSW 2006
  3. 3Sorbonne Université-UPMC, Pitié-Salpêtrière Hô, Neurophysiology Department (France, Paris), 47-83 Boulevard de l’Hôpital, 75013
  4. 4Institut national de la santé et de la recherche médicale Unit 1129 “Infantile Epilepsies and Brain Plasticity”, Paris Descartes University, Sorbonne Paris Cité University group, (France, Paris), 149 rue de Sévres 75015
  5. 5Brain and Spine Institute, Cortex and Epilepsie Group (France, Paris), 47 Boulevard Hôpital, 75013
  6. 6Paris Sciences & Lettres Research University, Laboratoire des Neurosciences Cognitives, Group for Neural Theory (France, Paris), 29, rue d'Ulm, 75005 France
  7. 7National Research University Higher School of Economics, Center for Cognition and Decision Making (Russia, Moscow), 20 Myasnitskaya, 109316
  1. Correspondence should be addressed to Anatoly Buchin at the above address, E-mail: anat.buchin{at}gmail.com.
  • ↵* A. Buchin’s present address: Allen Institute for Brain Science, Modelling Analysis and Theory, 615 Westlake Avenue North, Seattle, WA 98109.

View Full Text

Author contributions

  1. Author contributions: A.B., C.C.K., G.H., R.M., and B.G. designed research; A.B. and G.H. performed research; A.B. and C.C.K. analyzed data; A.B., C.C.K., G.H., R.M., and B.G. wrote the paper.

  • ↵* A. Buchin’s present address: Allen Institute for Brain Science, Modelling Analysis and Theory, 615 Westlake Avenue North, Seattle, WA 98109.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the Swartz Foundation, FRM FDT20140930942, ANR-10-LABX-0087 IEC, and ANR-10-IDEX-0001-02 PSL grants. B.G. was supported by funding from the RF (Russian Federation) Program 5-100 to the National Research University Higher School of Economics. C.C.K. was supported by the Australian Research Council (ARC) Discovery Early Career Researcher Award DE140101375.

Funding

  • Swartz Foundation

  • FRM

    FDT20140930942
  • PSL*

    ANR-10-LABX-0087 IEC; ANR-10-IDEX-0001-02 PSL
  • National Research University Higher School of Economics (HSE)

    RF Program 5-100
  • Australian Research Council (ARC)

    Discovery Early Career Researcher Award DE140101375

Other Version

  • You are viewing the most recent version of this article.
  • previous version (September 13, 2018).
  • previous version (September 13, 2018).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2025-12-06
to
E.g., 2025-12-06

Article usage: September 2018 to December 2025

AbstractFullPdf
Sep 2018378069
Oct 201819522660
Nov 201813221425
Dec 20185421113
Total 2018759651167
Jan 20192120911
Feb 20191318213
Mar 2019824725
Apr 20191121018
May 20191115316
Jun 20191118515
Jul 20191836918
Aug 2019877818
Oct 2019565021
Nov 2019545813
Dec 2019825013
Total 20191193691181
Jan 20205345
Feb 202063633
Mar 20201286
May 202006333
Jun 202016516
Jul 202021114
Aug 202014164
Sep 2020134117
Oct 2020811418
Nov 202096912
Dec 202079016
Total 202066667164
Jan 202115610
Feb 20212508
Mar 202128416
Apr 202116014
May 202156217
Jun 20211489
Jul 202125318
Aug 202165818
Sep 202124614
Oct 202124741
Nov 202116740
Dec 202106712
Total 202125698217
Jan 20220476
Feb 20221329
Mar 202243914
Apr 202223610
May 202206019
Jun 202226221
Jul 20225386
Aug 202243711
Sep 202222618
Oct 202223810
Nov 202233214
Dec 20220438
Total 202225490146
Jan 202344120
Feb 202314414
Mar 20231409
Apr 202313815
May 202303912
Jun 20230459
Jul 202314520
Aug 202323426
Sep 202323915
Oct 202384811
Nov 20232539
Dec 202376729
Total 202329533189
Jan 202464816
Feb 202494710
Mar 2024105314
Apr 2024126118
May 202425618
Jun 2024109314
Jul 202484512
Aug 202464423
Sep 202445532
Oct 202485716
Nov 202434112
Dec 202425619
Total 202480656204
Jan 202597026
Feb 2025310119
Mar 202557215
Apr 202507922
May 202517818
Jun 2025107828
Jul 2025189234
Aug 2025910638
Sep 20251625542
Oct 202588634
Nov 20251313118
Dec 20250131
Total 2025921161295
Total119585471563
Back to top

In this issue

eneuro: 5 (5)
eNeuro
Vol. 5, Issue 5
September/October 2018
  • Table of Contents
  • Index by author
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Adaptation and Inhibition Control Pathological Synchronization in a Model of Focal Epileptic Seizure
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Adaptation and Inhibition Control Pathological Synchronization in a Model of Focal Epileptic Seizure
Anatoly Buchin, Cliff C. Kerr, Gilles Huberfeld, Richard Miles, Boris Gutkin
eNeuro 13 September 2018, 5 (5) ENEURO.0019-18.2018; DOI: 10.1523/ENEURO.0019-18.2018

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Adaptation and Inhibition Control Pathological Synchronization in a Model of Focal Epileptic Seizure
Anatoly Buchin, Cliff C. Kerr, Gilles Huberfeld, Richard Miles, Boris Gutkin
eNeuro 13 September 2018, 5 (5) ENEURO.0019-18.2018; DOI: 10.1523/ENEURO.0019-18.2018
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Visual Abstract
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
    • Synthesis
    • Author Response
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • adaptation
  • AHP current
  • neural mass model
  • synaptic noise
  • temporal lobe epilepsy

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

New Research

  • A Very Fast Time Scale of Human Motor Adaptation: Within Movement Adjustments of Internal Representations during Reaching
  • Optogenetic Activation of β-Endorphin Terminals in the Medial Preoptic Nucleus Regulates Female Sexual Receptivity
  • Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses
Show more New Research

Disorders of the Nervous System

  • Altered PI3K/mTOR signaling within the forebrain leads to respiratory deficits in a mouse model of epilepsy
  • Lack of ADAP1/Centaurin-α1 Ameliorates Cognitive Impairment and Neuropathological Hallmarks in a Mouse Model of Alzheimer's Disease
  • The PDGFBB-PDGFRβ Pathway and Laminins in Pericytes Are Involved in the Temporal Change of AQP4 Polarity during Temporal Lobe Epilepsy Pathogenesis
Show more Disorders of the Nervous System

Subjects

  • Disorders of the Nervous System
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2025 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.