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Research ArticleNew Research, Cognition and Behavior

Prospective Analysis of the Effects of Maternal Immune Activation on Rat Cytokines during Pregnancy and Behavior of the Male Offspring Relevant to Schizophrenia

Brittney R. Lins, Jessica L. Hurtubise, Andrew J. Roebuck, Wendie N. Marks, Nadine K. Zabder, Gavin A. Scott, Quentin Greba, Wojciech Dawicki, Xiaobei Zhang, Christopher D. Rudulier, John R. Gordon and John G. Howland
eNeuro 14 August 2018, 5 (4) ENEURO.0249-18.2018; https://doi.org/10.1523/ENEURO.0249-18.2018
Brittney R. Lins
1Department of Physiology, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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Jessica L. Hurtubise
1Department of Physiology, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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Andrew J. Roebuck
1Department of Physiology, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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Wendie N. Marks
1Department of Physiology, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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Nadine K. Zabder
1Department of Physiology, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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Gavin A. Scott
1Department of Physiology, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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Quentin Greba
1Department of Physiology, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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Wojciech Dawicki
2Department of Medicine, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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Xiaobei Zhang
2Department of Medicine, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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Christopher D. Rudulier
1Department of Physiology, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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John R. Gordon
2Department of Medicine, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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John G. Howland
1Department of Physiology, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
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  • ORCID record for John G. Howland
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0249-18.2018
PubMed 
30225350
Published By 
Society for Neuroscience
History 
  • Received June 22, 2018
  • Revision received July 31, 2018
  • Accepted August 6, 2018
  • Published online August 14, 2018.
Copyright & Usage 
Copyright © 2018 Lins et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Brittney R. Lins1,
  2. Jessica L. Hurtubise1,
  3. Andrew J. Roebuck1,
  4. Wendie N. Marks1,
  5. Nadine K. Zabder1,
  6. Gavin A. Scott1,
  7. Quentin Greba1,
  8. Wojciech Dawicki2,
  9. Xiaobei Zhang2,
  10. Christopher D. Rudulier1,
  11. John R. Gordon2 and
  12. John G. Howland1
  1. 1Department of Physiology, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
  2. 2Department of Medicine, University of Saskatchewan, Saskatoon S7N 5E5, Saskatchewan, Canada
  1. Correspondence should be addressed to John G. Howland, Department of Physiology, University of Saskatchewan, GD30.7, Health Science Building, 107 Wiggins Road, Saskatoon S7N 5E5, Saskatchewan, Canada, E-mail: john.howland{at}usask.ca.
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Author contributions

  1. Author contributions: B.R.L., J.R.G., W.D., and J.G.H. designed research; B.R.L., J.L.H., A.J.R., W.N.M., N.K.Z., G.A.S., Q.G., X.Z., and C.D.R. performed research; B.R.L., J.L.H., W.N.M., and N.K.Z. analyzed data; B.R.L., J.L.H., W.N.M., and J.G.H. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the Canadian Institutes of Health Research (CIHR) Operating Grant 125984 (to J.G.H.). B.R.L. received salary support from the University of Saskatchewan. J.L.H. and W.N.M. received salary support from the College of Medicine at the University of Saskatchewan. G.A.S. is the recipient of an Natural Sciences and Engineering Research Council of Canada Postgraduate Scholarship D.

Funding

  • Gouvernement du Canada | Canadian Institutes of Health Research (CIHR)

    125984
  • University of Saskatchewan (U of S)

  • Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (NSERC)

Other Version

  • You are viewing the most recent version of this article.
  • previous version (August 14, 2018).

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AbstractFullPdf
Aug 2018319362
Sep 20182043454
Oct 20181129445
Nov 2018872534
Dec 2018332632
Total 2018755182227
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Feb 2019136511
Mar 2019256816
Apr 20191911323
May 2019208024
Jun 201965917
Jul 201976232
Aug 2019126325
Oct 201973914
Nov 201974915
Dec 201954914
Total 2019143699221
Jan 202053711
Feb 202093323
Mar 202083624
May 2020104217
Jun 202022614
Jul 202053422
Aug 202033714
Sep 2020105717
Oct 2020107717
Nov 2020114714
Dec 2020127221
Total 202085498194
Jan 202195921
Feb 2021124714
Mar 2021156620
Apr 202195911
May 202165912
Jun 202164611
Jul 202136219
Aug 202107229
Sep 202145320
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Total 202170696227
Jan 202218316
Feb 202256215
Mar 202266328
Apr 202253611
May 202216513
Jun 202236217
Jul 202225418
Aug 202213615
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Total 202232659198
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May 202313610
Jun 20230459
Jul 2023646822
Aug 202385831
Sep 202396516
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Total 2023591100185
Jan 20244634
Feb 2024277417
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May 2024157723
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Mar 202568331
Apr 202586224
May 2025106513
Jun 20251010547
Jul 20251110055
Aug 202567130
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Oct 2025129228
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Dec 2025108540
Total 20251181104386
Jan 20261416138
Feb 20261422424
Mar 20262022562
Apr 20262129574
May 202603517
Total 202669940215
Total144268162072
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Prospective Analysis of the Effects of Maternal Immune Activation on Rat Cytokines during Pregnancy and Behavior of the Male Offspring Relevant to Schizophrenia
Brittney R. Lins, Jessica L. Hurtubise, Andrew J. Roebuck, Wendie N. Marks, Nadine K. Zabder, Gavin A. Scott, Quentin Greba, Wojciech Dawicki, Xiaobei Zhang, Christopher D. Rudulier, John R. Gordon, John G. Howland
eNeuro 14 August 2018, 5 (4) ENEURO.0249-18.2018; DOI: 10.1523/ENEURO.0249-18.2018

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Prospective Analysis of the Effects of Maternal Immune Activation on Rat Cytokines during Pregnancy and Behavior of the Male Offspring Relevant to Schizophrenia
Brittney R. Lins, Jessica L. Hurtubise, Andrew J. Roebuck, Wendie N. Marks, Nadine K. Zabder, Gavin A. Scott, Quentin Greba, Wojciech Dawicki, Xiaobei Zhang, Christopher D. Rudulier, John R. Gordon, John G. Howland
eNeuro 14 August 2018, 5 (4) ENEURO.0249-18.2018; DOI: 10.1523/ENEURO.0249-18.2018
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Keywords

  • polyI:C
  • recognition memory
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